Results 101 to 110 of about 133,701 (287)

Thrombin cleaves membrane-bound endoglin potentially contributing to the heterogeneity of circulating endoglin in preeclampsia

open access: yesCommunications Biology
Increased levels of soluble endoglin (sEng) are found in serum, plasma, and urine of preeclampsia patients. sEng is released from membrane-bound endoglin through the proteolytic activity of metalloproteases, but its structural heterogeneity suggests the ...
Divina El Hamaoui   +14 more
doaj   +1 more source

In Vitro and in Silico Approach to Evaluate Hypoglycemic and Anti-Hemostasis Effects of Paederia Foetida in Managing Diabetes and Thrombophilia

open access: green, 2023
Jannatul Ferdous   +7 more
openalex   +1 more source

Injectable Chondroitin Sulfate Methacrylate Hydrogel Microspheres Co‐Loaded with GLPM Nanozyme, Dexamethasone, and Stem Cells for Synergistic Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng   +10 more
wiley   +1 more source

Modern view on hemostasis system: cell theory

open access: diamond, 2019
Ilya Schastlivtsev   +3 more
openalex   +2 more sources

A comparative study on changes in hemostasis in orthotopic and auxiliary liver transplantation in pigs [PDF]

open access: green, 1991
Robert J. Porte   +5 more
openalex   +1 more source

Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex

open access: yesAdvanced Science, EarlyView.
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang   +13 more
wiley   +1 more source

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang   +6 more
wiley   +1 more source

Cell‐free DNA for detection and monitoring of extramedullary AML relapse

open access: yesHemaSphere
Isolated extramedullary manifestations (IEM) of acute myeloid leukemia (AML) are recurrent events, especially following allogeneic hematopoietic cell transplantation (alloHCT).
Henri C. Hupe   +19 more
doaj   +1 more source

Mouse models of hemostasis

open access: green, 2020
Bassem M. Mohammed   +2 more
openalex   +2 more sources

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