Results 151 to 160 of about 238,098 (403)

Identification of NIBAN2‐Regulated RUNX2 Alternative Splicing Presents Novel Strategies for Antagonizing Osteoporosis

open access: yesAdvanced Science, EarlyView.
NIBAN2 interacts with the HNRNPU‐cored spliceosome complex and alters its components to regulate the alternative splicing of RUNX2, which ultimately cause an increase in functional RUNX2 (nuclear localization sequence complete) but a decrease in dysfunctional Runx2 (exon 6‐exclusive) isoforms to reinforce osteoblast differentiation.
Sheng Zhang   +9 more
wiley   +1 more source

Generation and pathogenicity of autoantibodies associated to thrombosis and hemostasis

open access: yesExploration of Immunology
Many acquired bleeding and thrombotic complications are provoked by autoantibodies to blood coagulation factors, or to hemostasis inhibitors and regulatory proteins.
Jean Amiral
doaj   +1 more source

Hemostasis in uncontrolled esophageal variceal bleeding by self-expanding metal stents. A systematic review [PDF]

open access: yes, 2016
Aim: The aim of this systematic review was to evaluate the current reported efficacy and the mortality rate of SEMS treatment in uncontrolled bleeding patients.
CICERONE, CLELIA   +5 more
core  

Reversible High‐Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation

open access: yesAdvanced Science, EarlyView.
A calcium‐dependent, specific biorecognition between coagulation factor Xa (FXa) and zeolite is discovered. It alters the prothrombin activation pathway to a more efficient mechanism by mimicking the FXa/factor Va (FXa/FVa) interaction formed during the natural coagulation cascade.
Chaojie Shi   +9 more
wiley   +1 more source

Predictive Factors for Second-Line Therapy in Metastatic Renal Cell Carcinoma: A Retrospective Analysis

open access: yesJournal of Kidney Cancer and VHL, 2017
Currently, about 50% of patients with metastatic renal cell carcinoma (mRCC) receive a second-line therapy. Therefore, the choice at each subsequent treatment line remains an important issue.
Hendrik Eggers   +3 more
doaj   +1 more source

Morphology Effect of Puffball Spores on Hemostasis: A Promising Solution for Hemostatic Challenges

open access: yesAdvanced Science, EarlyView.
This work presents an innovative approach to address current challenges in hemostasis by drawing inspiration from the natural hemostatic material, Puffball spores (Bovistella sp.). Their unique hollow ball‐rod morphology and texture composition enable blood concentration and promote the release of procoagulant factors, while the nano‐protrusions on the
Xuechang Pei   +12 more
wiley   +1 more source

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