Results 11 to 20 of about 127,436 (249)

Generation of functional liver sinusoidal endothelial-like cells from human bone marrow-derived mesenchymal stem cells

open access: yesRegenerative Therapy, 2023
Introduction: Liver sinusoidal endothelial cells (LSECs) are specialized vascular endothelial cells that play an important role in the maintenance of biological homeostasis.
Seiji Mitani   +6 more
doaj   +1 more source

Hibernation and hemostasis

open access: yesFrontiers in Physiology, 2023
Hibernating mammals have developed many physiological adaptations to accommodate their decreased metabolism, body temperature, heart rate and prolonged immobility without suffering organ injury. During hibernation, the animals must suppress blood clotting to survive prolonged periods of immobility and decreased blood flow that could otherwise lead to ...
Edwin L. De Vrij   +5 more
openaire   +3 more sources

Allopurinol-induced acquired von Willebrand syndrome

open access: yesBleeding, Thrombosis and Vascular Biology, 2023
Acquired von Willebrand syndrome (AVWS) is a relatively infrequent but often overlooked finding when testing for von Willebrand factor (VWF) levels in a patient with mucocutaneous bleeding.
Juan Eirís   +5 more
doaj   +1 more source

Gut Microbiota Promote Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background The gut microbiome is essential for physiological host responses and development of immune functions. The impact of gut microbiota on blood pressure and systemic vascular function, processes that are determined by immune cell function, is ...
Susanne H. Karbach   +16 more
doaj   +1 more source

Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation

open access: yesScientific Reports, 2017
Under ischemic conditions, tissues are exposed to hypoxia. Although human physiology, to a certain extent, can adapt to hypoxic conditions, the impact of low oxygen levels on platelet function is unresolved.
Klytaimnistra Kiouptsi   +5 more
doaj   +1 more source

Recurrence risk after anticoagulant treatment of limited duration for late, second venous thromboembolism

open access: yesHaematologica, 2015
Patients with a second venous thromboembolism generally receive anticoagulant treatment indefinitely, although it is known that the recurrence risk diminishes over time while the risk of hemorrhage persists with continued anticoagulation and increases ...
Tom van der Hulle   +7 more
doaj   +1 more source

A compound heterozygote for lipoprotein lipase deficiency, Val69–>Leu and Gly188–>Glu: correlation between in vitro LPL activity and clinical expression.

open access: yesJournal of Lipid Research, 1994
We analyzed the molecular defects in the lipoprotein lipase gene of a patient with type I hyperlipidemia suffering from recurrent pancreatitis, indicative for lipoprotein lipase deficiency.
T. Bruin   +6 more
doaj   +1 more source

Calcium Prevents Enhanced Degradation of Factor VIII in the Condition of Motion

open access: yesBiology, 2023
Background: Hemophilia A and B induce recurrent bleeding episodes, mainly in skeletal muscles and joints that are in intermittent motion. We have previously demonstrated that intermittent motion contributes to increased degradation of factors VIII and IX.
Haim Cohen   +5 more
doaj   +1 more source

MicroRNAs in hemostasis [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2015
Epidemiologic studies have revealed that modification of the levels of individual components of the hemostatic system may have effects on the development of thrombosis or hemorrhage. To maintain the necessary equilibrium, the hemostatic system is finely regulated.
Teruel-Montoya, R.   +2 more
openaire   +3 more sources

Tannins as Hemostasis Modulators [PDF]

open access: yesFrontiers in Pharmacology, 2022
The hemostasis system is often affected by complications associated with cardiovascular diseases, which results in thromboembolic events. Compounds of plant origin and plant extracts are considered as a promising source of substances that could modulate the functioning of the hemostasis system and thus reduce the risk of thromboembolism.
Natalia Marcińczyk   +3 more
openaire   +3 more sources

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