Results 21 to 30 of about 163,460 (311)

Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation

Scientific Reports, 2017
Under ischemic conditions, tissues are exposed to hypoxia. Although human physiology, to a certain extent, can adapt to hypoxic conditions, the impact of low oxygen levels on platelet function is unresolved.
Klytaimnistra Kiouptsi, Stepan Gambaryan, Elena Walter, Ulrich Walter, Kerstin Jurk, Christoph Reinhardt   +5 more
doaj   +1 more source

A compound heterozygote for lipoprotein lipase deficiency, Val69–>Leu and Gly188–>Glu: correlation between in vitro LPL activity and clinical expression.

Journal of Lipid Research, 1994
We analyzed the molecular defects in the lipoprotein lipase gene of a patient with type I hyperlipidemia suffering from recurrent pancreatitis, indicative for lipoprotein lipase deficiency.
T. Bruin, S. Tuzgöl, W.J. Mulder, A.E. van den Ende, H. Jansen, M.R. Hayden, J.J. Kastelein   +6 more
doaj   +1 more source

Tannins as Hemostasis Modulators [PDF]

Frontiers in Pharmacology, 2022
The hemostasis system is often affected by complications associated with cardiovascular diseases, which results in thromboembolic events. Compounds of plant origin and plant extracts are considered as a promising source of substances that could modulate the functioning of the hemostasis system and thus reduce the risk of thromboembolism.
Natalia Marcińczyk, Anna Gromotowicz-Popławska, Michał Tomczyk, Ewa Chabielska   +3 more
openaire   +3 more sources

Calcium Prevents Enhanced Degradation of Factor VIII in the Condition of Motion

Biology, 2023
Background: Hemophilia A and B induce recurrent bleeding episodes, mainly in skeletal muscles and joints that are in intermittent motion. We have previously demonstrated that intermittent motion contributes to increased degradation of factors VIII and IX.
Haim Cohen, Anat Keren-Politansky, Yonatan Crispel, Chen Yanovich, Keren Asayag, Yona Nadir   +5 more
doaj   +1 more source

Hemostasis

, 2023
Hemostasis is a complex balance in which anticoagulant forces contribute to maintaining the fluidity of the blood within intact vessels and procoagulant forces act instead to avoid an excessive outflow of blood when the vessels lose their integrity ...
Franchini, Massimo, Salvagno, Gian Luca, Lippi, Giuseppe   +2 more
core   +1 more source

Impaired thrombin generation in Reelin-deficient mice: a potential role of plasma Reelin in hemostasis

, 2017
BackgroundReelin is a large extracellular glycoprotein that is present in the peripheral blood. That Reelin interacts with the coagulation components and elicits a functional role in hemostasis has not yet been elucidated.
Tseng, W. -L.;Chen, T. -H.;Huang, C. -C.;Huang, Y. -H.;Yeh, C. -F.;Tsai, H. -J.;Lee, H. -Y.;Kao, C. -Y.;Lin, S. -W.;Liao, H. -R.;Cheng, J. -C.;Ts, C. -P., 林淑華   +1 more
core   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Effect of bone marrow blood versus peripheral blood on the hemostatic balance of osteoblasts and endothelial cells

Scientific Reports
Bone and bone-marrow (BM) have the same blood supply and thus may be considered as one organ. We previously demonstrated that the microcirculation hemostatic balance that includes heparanase, tissue factor (TF), TF pathway inhibitor (TFPI) and TFPI-2 are
Keren Asayag, Eli Peled, Yonatan Crispel, Chen Yanovich, Haim Cohen, Anat Keren-Politansky, Yona Nadir   +6 more
doaj   +1 more source

Evaluation of the DOAC-Stop® Procedure to Overcome the Effect of DOACs on Several Thrombophilia Screening Tests

TH Open, 2018
The impact of direct oral anticoagulants (DOACs) on laboratory assays used for thrombophilia testing (e.g., antithrombin, protein S, protein C, lupus anticoagulant and activated protein-C resistance) is a well-known issue and may cause false-positive and
Julien Favresse, Benjamin Lardinois, Lina Sabor, Bérangère Devalet, Julie Vandepapeliere, Maximilien Braibant, Sarah Lessire, Bernard Chatelain, Hugues Jacqmin, Jonathan Douxfils, François Mullier   +10 more
doaj   +1 more source