Results 21 to 30 of about 168,010 (264)
, 2023 Hemostasis is a complex balance in which anticoagulant forces contribute to maintaining the fluidity of the blood within intact vessels and procoagulant forces act instead to avoid an excessive outflow of blood when the vessels lose their integrity ...
Franchini, Massimo +2 more
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Hemostasis – compendium for students [PDF]
, 2020 Hemostasis is one of many well-known systems that ensure a constant conditions of the organism's internal environment. This process is usually divided into two main stages: coagulation and fibrinolysis.
Znajewska-Szulc, Karolina +6 more
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, 2020 Hemostasis is the normal process that produces a blood clot at a site of vascular injury. Mice are widely used to study hemostasis and abnormalities of blood coagulation because their hemostatic system is similar in most respects to that of humans, and ...
David Gailani +2 more
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, 2017 BackgroundReelin is a large extracellular glycoprotein that is present in the peripheral blood. That Reelin interacts with the coagulation components and elicits a functional role in hemostasis has not yet been elucidated.
Tseng, W. -L.;Chen, T. -H.;Huang, C. -C.;Huang, Y. -H.;Yeh, C. -F.;Tsai, H. -J.;Lee, H. -Y.;Kao, C. -Y.;Lin, S. -W.;Liao, H. -R.;Cheng, J. -C.;Ts, C. -P. +1 more
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Milestones and perspectives in coagulation and hemostasis.
, 2009 Hemostasis is traditionally defined as the physiologic process whereby bleeding is antagonized and possibly stopped to minimize blood loss. The first medical description of the clinical and inherited features of hemostasis can be dated back more than ...
Favaloro EJ +3 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Scientific ReportsBone and bone-marrow (BM) have the same blood supply and thus may be considered as one organ. We previously demonstrated that the microcirculation hemostatic balance that includes heparanase, tissue factor (TF), TF pathway inhibitor (TFPI) and TFPI-2 are
Keren Asayag +6 more
doaj +1 more source
Effectiveness and Safety of Apixaban for Treatment of Venous Thromboembolism in Daily Practice
TH Open, 2020 Introduction Phase 3 trials have shown comparable efficacy of direct oral anticoagulants (DOACs) and vitamin K antagonists in patients with acute venous thromboembolism (VTE), with less major bleeding events in patients randomized to DOAC treatment. With
Stephan V. Hendriks +6 more
doaj +1 more source
Frontiers in Immunology, 2023 The propensity of therapeutic proteins to elicit an immune response, poses a significant challenge in clinical development and safety of the patients. Assessment of immunogenicity is crucial to predict potential adverse events and design safer biologics.
Wojciech Jankowski +5 more
doaj +1 more source