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Hemostasis

2023
Inflammation and coagulation are tightly connected, whereby an inflammatory host response will activate coagulation, resulting in a spectrum of coagulopathies that range from a mildly decreased platelet count to disseminated intravascular coagulation (DIC).
Dujardin, Romein W.G.   +2 more
openaire   +4 more sources

An Integrated Strategy for Rapid Hemostasis during Tumor Resection and Prevention of Postoperative Tumor Recurrence of Hepatocellular Carcinoma by Antibacterial Shape Memory Cryogel.

Small, 2021
The inevitable bleeding during tumor resection greatly increases the risk of tumor recurrence caused by metastasis of cancer cells with blood, and hemostasis and prevention of post-operation tumor recurrence is still a challenge.
Yongping Liang   +3 more
semanticscholar   +1 more source

Tissue Factor: An Essential Mediator of Hemostasis and Trigger of Thrombosis

Arteriosclerosis, Thrombosis and Vascular Biology, 2018
Tissue factor (TF) is the high-affinity receptor and cofactor for factor (F)VII/VIIa. The TF-FVIIa complex is the primary initiator of blood coagulation and plays an essential role in hemostasis. TF is expressed on perivascular cells and epithelial cells
S. Grover, N. Mackman
semanticscholar   +1 more source

Thrombin: A Pivotal Player in Hemostasis and Beyond

Seminars in Thrombosis and Hemostasis, 2021
The serine protease thrombin, a naturally derived enzyme, plays a key role in hemostasis by converting fibrinogen to fibrin and activating coagulation factor XIII whereby the fibrin clot is stabilized.
J. Larsen, A. Hvas
semanticscholar   +1 more source

Hemostasis in malignancy

American Journal of Hematology, 1990
AbstractHemostatic abnormalities are present in a majority of patients with metastatic cancer. These abnormalities can be categorized as 1) increased platelet aggregation and activation, 2) abnormal activation of coagulation cascade, 3) release of plasminogen activator, and 4) decreased hepatic synthesis of anticoagulant proteins like Protein C and ...
Harry L. Messmore, Sucha Nand
openaire   +3 more sources

Monitoring of Hemostasis

2012
Abstract non ...
GIANSANTE, CARLO, FIOTTI, NICOLA
openaire   +3 more sources

The physiology of hemostasis

Blood Coagulation & Fibrinolysis, 2022
The breakdown of vascular integrity triggers a series of reactions, initially involving a vasoconstriction phenomenon that reduces blood loss and leads to platelet plug formation under changing flow conditions. Once the platelet plug has formed, the coagulation system is activated in order to allow the formation of fibrin ...
Cristina, Sierra   +2 more
openaire   +2 more sources

Hemostasis

2017
Hemostasis is the process that stops blood loss from a damaged vessel. Blood clotting is achieved by a cascade of enzymatic reactions, which involves a series of factors. Among them are the zymogens prekallikrein, prothrombin, factors VII, IX, X, XI, and XII, which are converted to active proteases by hydrolysis.
Antonio Blanco, Gustavo Blanco
openaire   +2 more sources

A biodegradable antibacterial nanocomposite based on oxidized bacterial nanocellulose for rapid hemostasis and wound healing.

ACS Applied Materials and Interfaces, 2019
The development of biodegradable and antibacterial hemostatic materials with high blood absorption to halt the internal hemorrhage of deep non-compressible wounds remains a challenge.
Haibin Yuan, Lin Chen, Feng F. Hong
semanticscholar   +1 more source

Tetra‐PEG Based Hydrogel Sealants for In Vivo Visceral Hemostasis

Advances in Materials, 2019
Medical sealant devices for in vivo hemostasis are far from satisfactory in the aged society. A major challenge is effective integration of quick hemorrhage control of the increased anticoagulated patients, high safety, and facile accessibility.
Yazhong Bu   +7 more
semanticscholar   +1 more source

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