Results 71 to 80 of about 214,361 (343)

P468: MRD AS A BIOMARKER FOR RESPONSE TO DONOR LYMPHOCYTE INFUSION AFTER AL-LOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION IN PATIENTS WITH ACUTE MYELOID LEUKEMIA

HemaSphere, 2022
K. Teich, M. Stadler, R. Gabdoulline, C. Wienecke, B. Heida, P. Klement, K. Büttner, L. Venturini, M. Wichmann, W. Puppe, C. Schultze-Florey, G. Beutel, M. Eder, A. Ganser, M. Heuser, F. Thol   +15 more
doaj   +1 more source

Injectable Dual‐Crosslinked Poly(oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Injectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...
Gurpreet Kaur Randhawa, Meghan Kostashuk, Zhicheng Pan, Nils Nordstrom, Thomas Kalab, Erica Winterhelt, Todd Hoare   +6 more
wiley   +1 more source

Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds

Advanced Healthcare Materials, EarlyView.
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar, Diego Caicedo‐Valdés, Susana B. Bravo, Isabel Rodriguez‐Moldes, Salvador D. Aznar‐Cervantes, Angel Concheiro, Carmen Alvarez‐Lorenzo, Luis Diaz‐Gomez   +7 more
wiley   +1 more source

Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men [PDF]

, 2009
Aims: The extent to which hemostatic and inflammatory biomarkers are related to angina pectoris as compared with myocardial infarction (MI) remains uncertain.
Lennon, L, Lowe, GD, Rumley, A, Shaper, AG, Wannamethee, SG, Whincup, PH   +5 more
core   +1 more source

Formulating Smart All‐in‐One Chitosan Hydrogel for High Performance Wound Dressing

Advanced Healthcare Materials, EarlyView.
An innovative approach to fabricating a thermosensitive, highly swelling, degradable, and antibacterial hydrogel composed of a chitosan‐g‐NIPAAm/PVA/PVP copolymer, integrated with AgNPs, for use in wound dressing applications. The hydrogel demonstrates enhanced performance, accelerating the wound healing process.
Chia‐Chi Lin, Andi Magattang Gafur Muchlis, Ren‐Jei Chung, Ssu Yu Huang, Michal Martinka, Syang‐Peng Rwei, Aivaras Kareiva, Jen‐Chang Yang, Chun Che Lin   +8 more
wiley   +1 more source

Evaluating the Effectiveness of Prophylactic Strategies for Hemophilia A Management: A Real-World, Longitudinal Observational Study

Drugs - Real World Outcomes
Background Hemophilia A (HA) treatment strategies aim to manage bleeding episodes and improve patients' quality of life. This study investigates the effectiveness of a preventative approach using intermediate-dose prophylaxis with standard half-life ...
Shyh-Shin Chiou, Ching-Yeh Lin, Te-Fu Weng, Jiaan-Der Wang, Sheng-Chieh Chou, Ching-Tien Peng, Pei-Chin Lin, Yu-Mei Liao, Leanne Lai, Ming-Ching Shen, Taiwan Society of Thrombosis, Hemostasis (TSTH) Study Group   +10 more
doaj   +1 more source

Injectable Deep Eutectic Solvent‐Based Ionic Gel With Rapid Gelation and Broad Hemostatic Functionality

Advanced Healthcare Materials, EarlyView.
An injectable deep eutectic solvent‐based ionic gel is developed for rapid in situ gelation and broad‐spectrum hemostatic functionality. The material combines high mechanical strength, strong tissue adhesion, and antibacterial activity, demonstrating potential as an advanced biofunctional gel for emergency bleeding control and wound care.
Jia‐Yu Yang, En‐Yu Zhou, Ting‐Hui Cheng, Pin‐Hung Liu, Wen‐Ching Hsieh, Hui‐Ching Cheng, Yi‐Kai Hong, Yu‐Chen Lin, Yi‐Chiung Hsu, Chao‐Chun Yang, Chao‐Kai Hsu, Li‐Chieh Kuo, Shang‐Chin Hsieh, Cheng‐Hsin Chuang   +13 more
wiley   +1 more source

Engineering and evaluation of FXa bypassing agents that restore hemostasis following Apixaban associated bleeding

Nature Communications
Direct oral anticoagulants (DOACs) targeting activated factor Xa (FXa) are used to prevent or treat thromboembolic disorders. DOACs reversibly bind to FXa and inhibit its enzymatic activity.
Wojciech Jankowski, Stepan S. Surov, Nancy E. Hernandez, Atul Rawal, Marcos Battistel, Daron Freedberg, Mikhail V. Ovanesov, Zuben E. Sauna   +7 more
doaj   +1 more source

Alternative trafficking of Weibel‐Palade body proteins in CRISPR/Cas9‐engineered von Willebrand factor–deficient blood outgrowth endothelial cells

Research and Practice in Thrombosis and Haemostasis, 2019
Background Synthesis of the hemostatic protein von Willebrand factor (VWF) drives formation of endothelial storage organelles called Weibel‐Palade bodies (WPBs).
Maaike Schillemans, Marije Kat, Jurjen Westeneng, Anastasia Gangaev, Menno Hofman, Benjamin Nota, Floris P. J. van Alphen, Martin de Boer, Maartje van den Biggelaar, Coert Margadant, Jan Voorberg, Ruben Bierings   +11 more
doaj   +1 more source

RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists. [PDF]

, 2018
Platelets express ≥2 members of the regulators of G protein signaling (RGS) family. Here, we have focused on the most abundant, RGS10, examining its impact on the hemostatic response in vivo and the mechanisms involved.
Brass, Lawrence F., DeHelian, Daniel, Gupta, Shuchi, Ma, Peisong, Sampietro, Sara, Stalker, Timothy J., Tang, Alan, Tutwiler, Valerie   +7 more
core   +1 more source