Results 71 to 80 of about 3,221,536 (372)

Gelatin-based hemostatic agents for medical and dental application at a glance: A narrative literature review

Saudi Dental Journal, 2022
Uncontrolled bleeding is linked to higher treatment costs, risk of post-surgical infection and increased disease and death. Hemostatic agents are used to treat excessive bleeding.
Nining Irfanita Irfan, Amir Zulhakim Mohd Zubir, Asrul Suwandi, Muhammad Salahuddin Haris, Irwandi Jaswir, Widya Lestari   +5 more
doaj  

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

Engineering Highly Cellularized Living Materials via Mechanical Agitation

Advanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani, Shiyu Liu, Evan Johnston, Weiyi Wan, Xiaoyi Lan, Tianqin Ning, Alexander Nottegar, Ran Huo, Shuaibing Jiang, Jianyu Li   +9 more
wiley   +1 more source

Management of Noncatastrophic Internal Carotid Artery Injury in Endoscopic Skull Base Surgery. [PDF]

, 2019
Arterial injuries are the most feared complication of endoscopic skull base surgery. During resection of the middle fossa component of a large ventral skull base chondrosarcoma, arterial bleeding was encountered near the right internal carotid artery ...
El-Sayed, Ivan H, Safaee, Michael, Theodosopoulos, Philip V, Young, Jacob S   +3 more
core  

Chitosan-Cellulose Composite for Wound Dressing Material. Part 2. Antimicrobial Activity, Blood Absorption Ability, and Biocompatibility [PDF]

, 2014
Chitosan (CS), a polysaccharide derived from chitin, the second most abundant polysaccharide, is widely used in the medical world because of its natural and nontoxic properties and its innate ability for antibacterial and hemostasis effects.
Altiok, Anderson, Anderson, Augustine, Aziz, Bordenave, Burkatovskaya, Burkatovskaya, Burkatovskaya, Cai, Cai, Chatelet, Costerton, Dai, Dai, El-Mekawy, Fakhry, Fink, Finkenstadt, Fulton, Ignatova, Ignatova, Jain, Jayakumar, Jayakumar, Kiyozumi, Kloth, Kong, Lee, Miao, Mori, Mori, Naficy, Oliveira, Pinto, Rabea, Rabea, Sandoval, Silva, Silva, Spoering, Terrill, Tran, Varshosaz, Werner, Wu, Xia   +46 more
core   +2 more sources

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

Maintaining therapeutic activity in the operating room: compatibility of a gamma-retroviral replicating vector with clinical materials and biofluids

Molecular Therapy: Methods & Clinical Development, 2014
Toca 511 is a novel retroviral replicating vector, encoding a modified yeast cytosine deaminase, administered to recurrent high grade glioma patients in Phase 1 trials by stereotactic, transcranial injection into the tumor or into the walls of the ...
Ryan Burnett, Carlos E. Ibañez, Pär L. Pettersson, Ching-I Chen, Shraddha Parab, Tiffany Huang, Joan Robbins, Krystof Bankiewicz, Manish Aghi, Christopher Logg, Noriyuki Kasahara, Dan Pertschuk, Harry E. Gruber, Douglas J. Jolly   +13 more
doaj   +1 more source

Application of Alginate-Based Hydrogels in Hemostasis

Gels, 2022
Hemorrhage, as a common trauma injury and clinical postoperative complication, may cause serious damage to the body, especially for patients with huge blood loss and coagulation dysfunction.
Yue Xie, Pan Gao, Fangfang He, Chun Zhang   +3 more
doaj   +1 more source

Autologous fibrin sealant (Vivostat®) in the neurosurgical practice: Part I: Intracranial surgical procedure [PDF]

, 2015
Background: Hemorrhages, cerebrospinal fluid (CSF) fistula and infections are the most challenging postoperative complications in Neurosurgery. In this study, we report our preliminary results using a fully autologous fibrin sealant agent, the Vivostat ...
Basile, L., Certo, F., Ganau, M., GRASSO, Giovanni, Graziano, Francesca, IACOPINO, Domenico, Maugeri, R., Meccio, F.   +7 more
core   +2 more sources

Coagulation Matters: ATIII‐Enriched Biomolecular Corona Enhances the Hemocompatibility of PEG Nanoparticles

Advanced Healthcare Materials, EarlyView.
Engineering of a functional protein corona with a synergistic heparin‐ATIII complex significantly improves hemocompatibility of PEG nanoparticles. Through deliberate engineering of the protein corona, a 4‐fold reduction in coagulation activation (F1 + 2) without inducing adverse thromboinflammatory reactions (CD11b, C5a) is achieved without disrupting ...
Vaidehi Londhe, Manfred F. Maitz, Triantafyllos Chavakis, Carsten Werner, Alessia C. G. Weiss, Quinn A. Besford   +5 more
wiley   +1 more source