Results 41 to 50 of about 7,362 (172)

Intensive Chemotherapy With or Without Midostaurin in Adults ≥ 60 Years Old With FLT3‐Mutated AML: A FILO‐DATAML‐PETHEMA Real‐World Study

open access: yesAmerican Journal of Hematology, Volume 101, Issue 5, Page 949-960, May 2026.
ABSTRACT The addition of midostaurin (MIDO) to intensive chemotherapy (IC) improves survival in younger adults with FLT3‐mutated acute myeloid leukemia (AML); however, real‐world data in elderly patients (≥ 60 years) are limited. This large, retrospective, multicenter study from three European registries (PETHEMA, FILO, DATAML) evaluated MIDO+IC (n ...
Gaspar Aspas Requena   +31 more
wiley   +1 more source

Digital PCR‐based non‐invasive prenatal diagnosis should be considered in the evolving diagnostic pathway for sickle cell disease

open access: yes
HemaSphere, Volume 10, Issue 8, August 2026.
Paloma Ropero   +5 more
wiley   +1 more source

The Effect of Photobiomodulation in the Management of Leg Ulcers in Sickle Cell Disease: A Systematic Review

open access: yesInternational Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Leg ulcer (LU) is a chronic complication of sickle cell disease (SCD), characterised by intense pain, treatment resistance and a high impact on the patient's quality of life (QoL), representing a significant public health challenge. Clinical management involves multifaceted approaches; however, the variability in response to conventional ...
Jéssica Eutímio de Carvalho Silva   +5 more
wiley   +1 more source

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

open access: yesCytometry Part B: Clinical Cytometry, Volume 110, Issue 2, Page 128-133, March 2026.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva   +7 more
wiley   +1 more source

Descarte de bolsas de sangue devido à reatividade para doença de Chagas em um laboratório de triagem sorológica de doadores em Porto Alegre-RS Disposal of blood units due to reactivity for Chagas' disease in a blood donor serological screening laboratory in Porto Alegre, Brazil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2009
A transmissão transfusional (DCT) da doença de Chagas foi aventada nos anos 30 e comprovada nos anos 50. Inicialmente a sorologia pré-transfusional não era obrigatória e nas décadas seguintes os testes foram aperfeiçoados com técnicas mais adaptadas e ...
Douglas B. Fitarelli, Joel F. Horn
doaj  

Integrated humoral and inflammatory signatures predict outcomes in severe COVID‐19: a 14‐day longitudinal analysis

open access: yesClinical &Translational Immunology, Volume 15, Issue 2, 2026.
Integrated longitudinal profiling of humoral and inflammatory mediators in critically ill COVID‐19 patients revealed distinct immune trajectories associated with clinical outcomes. Nonsurvivors exhibited early IgM‐dominant responses accompanied by persistent inflammatory activation and fragmented immune networks, whereas survivors showed coordinated ...
Hiochelson Najibe Santos Ibiapina   +23 more
wiley   +1 more source

Type 1 and CD103+ Type 2 Conventional Dendritic Cells Are Decreased in Active Patients with Ulcerative Colitis but Not with Crohn's Disease

open access: yesEuropean Journal of Immunology, Volume 56, Issue 2, February 2026.
Human lamina propia mononuclear cells (LPMC) were isolated from intestinal biopsies and resections, as well as peripheral blood mononuclear cells (PBMC) from blood. Using flow cytometry approaches, we characterized cDC subsets and assessed their functional capacity through T‐cell coculture assays (after isolation of the different subsets of cDC using ...
Elisa Arribas‐Rodríguez   +18 more
wiley   +1 more source

Co‐inheritance of ITGA2B and TUBB1 variants in a family reveals distinct genetic contributions to platelet dysfunction

open access: yes
British Journal of Haematology, Volume 208, Issue 6, Page 2298-2303, June 2026.
Perla Bandini   +12 more
wiley   +1 more source

Shared Decision‐Making in Treatment Selection in Multiple Myeloma in Spain: The PRISMMA Study

open access: yesEuropean Journal of Haematology, Volume 116, Issue 2, Page 185-194, February 2026.
ABSTRACT Introduction Perceptions and experiences of shared decision‐making between patients and physicians in multiple myeloma (MM) care are not fully understood. A survey study was conducted to explore these perspectives in Spain. Methods Two anonymous online surveys, one for haematologists and one for MM patients, were developed.
Valentín Cabañas   +5 more
wiley   +1 more source

Invaginación intestinal irreductible. Resección intestinal en un caso de hemofilia A

open access: yesCirugía del Uruguay, 1972
Los autores presentan una observación correspondiente a una invaginación intestinal de un niño, tratada con éxito quirúrgicamente, en un caso de hemofilia. Se hacen consideraciones sobre el tratamiento hemoterápico efectuado.
A F Rosa   +3 more
doaj  

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