Results 41 to 50 of about 7,362 (172)
ABSTRACT The addition of midostaurin (MIDO) to intensive chemotherapy (IC) improves survival in younger adults with FLT3‐mutated acute myeloid leukemia (AML); however, real‐world data in elderly patients (≥ 60 years) are limited. This large, retrospective, multicenter study from three European registries (PETHEMA, FILO, DATAML) evaluated MIDO+IC (n ...
Gaspar Aspas Requena +31 more
wiley +1 more source
ABSTRACT Leg ulcer (LU) is a chronic complication of sickle cell disease (SCD), characterised by intense pain, treatment resistance and a high impact on the patient's quality of life (QoL), representing a significant public health challenge. Clinical management involves multifaceted approaches; however, the variability in response to conventional ...
Jéssica Eutímio de Carvalho Silva +5 more
wiley +1 more source
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva +7 more
wiley +1 more source
A transmissão transfusional (DCT) da doença de Chagas foi aventada nos anos 30 e comprovada nos anos 50. Inicialmente a sorologia pré-transfusional não era obrigatória e nas décadas seguintes os testes foram aperfeiçoados com técnicas mais adaptadas e ...
Douglas B. Fitarelli, Joel F. Horn
doaj
Integrated longitudinal profiling of humoral and inflammatory mediators in critically ill COVID‐19 patients revealed distinct immune trajectories associated with clinical outcomes. Nonsurvivors exhibited early IgM‐dominant responses accompanied by persistent inflammatory activation and fragmented immune networks, whereas survivors showed coordinated ...
Hiochelson Najibe Santos Ibiapina +23 more
wiley +1 more source
Human lamina propia mononuclear cells (LPMC) were isolated from intestinal biopsies and resections, as well as peripheral blood mononuclear cells (PBMC) from blood. Using flow cytometry approaches, we characterized cDC subsets and assessed their functional capacity through T‐cell coculture assays (after isolation of the different subsets of cDC using ...
Elisa Arribas‐Rodríguez +18 more
wiley +1 more source
British Journal of Haematology, Volume 208, Issue 6, Page 2298-2303, June 2026.
Perla Bandini +12 more
wiley +1 more source
Shared Decision‐Making in Treatment Selection in Multiple Myeloma in Spain: The PRISMMA Study
ABSTRACT Introduction Perceptions and experiences of shared decision‐making between patients and physicians in multiple myeloma (MM) care are not fully understood. A survey study was conducted to explore these perspectives in Spain. Methods Two anonymous online surveys, one for haematologists and one for MM patients, were developed.
Valentín Cabañas +5 more
wiley +1 more source
Invaginación intestinal irreductible. Resección intestinal en un caso de hemofilia A
Los autores presentan una observación correspondiente a una invaginación intestinal de un niño, tratada con éxito quirúrgicamente, en un caso de hemofilia. Se hacen consideraciones sobre el tratamiento hemoterápico efectuado.
A F Rosa +3 more
doaj

