Results 51 to 60 of about 10,187 (218)

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

open access: yesCytometry Part B: Clinical Cytometry, Volume 110, Issue 2, Page 128-133, March 2026.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva   +7 more
wiley   +1 more source

Guidelines On The Treatment Of Acute Myeloid Leukemia: Associação Brasileira De Hematologia, Hemoterapia E Terapia Celular [PDF]

open access: yes, 2017
381587
Teresa Cristina; Chauffaille   +7 more
core  

Integrated humoral and inflammatory signatures predict outcomes in severe COVID‐19: a 14‐day longitudinal analysis

open access: yesClinical &Translational Immunology, Volume 15, Issue 2, 2026.
Integrated longitudinal profiling of humoral and inflammatory mediators in critically ill COVID‐19 patients revealed distinct immune trajectories associated with clinical outcomes. Nonsurvivors exhibited early IgM‐dominant responses accompanied by persistent inflammatory activation and fragmented immune networks, whereas survivors showed coordinated ...
Hiochelson Najibe Santos Ibiapina   +23 more
wiley   +1 more source

TRAÇO FALCIFORME: UMA VISÃO PARA OS CENTROS DE HEMOTERAPIA

open access: yes, 2011
As Hemoglobinopatias são desordens hereditárias muito freqüentes que afetam toda a população mundial e causam um grande problema de saúde pública.
Paz da Silva, José Edson   +1 more
core   +2 more sources

Type 1 and CD103+ Type 2 Conventional Dendritic Cells Are Decreased in Active Patients with Ulcerative Colitis but Not with Crohn's Disease

open access: yesEuropean Journal of Immunology, Volume 56, Issue 2, February 2026.
Human lamina propia mononuclear cells (LPMC) were isolated from intestinal biopsies and resections, as well as peripheral blood mononuclear cells (PBMC) from blood. Using flow cytometry approaches, we characterized cDC subsets and assessed their functional capacity through T‐cell coculture assays (after isolation of the different subsets of cDC using ...
Elisa Arribas‐Rodríguez   +18 more
wiley   +1 more source

Gaucher disease treatment: a Brazilian consensus

open access: yes, 2003
Gaucher disease is one of the inborn errors of metabolism from lysossomal storage diseases and the most frequent of this group. It iss an autosomal recessive disease with reoccurrence risk of 25% in each pregnancy of hetrozygotes parents.
Lobo, Clarisse L.   +13 more
core   +1 more source

Co‐inheritance of ITGA2B and TUBB1 variants in a family reveals distinct genetic contributions to platelet dysfunction

open access: yes
British Journal of Haematology, Volume 208, Issue 6, Page 2298-2303, June 2026.
Perla Bandini   +12 more
wiley   +1 more source

Shared Decision‐Making in Treatment Selection in Multiple Myeloma in Spain: The PRISMMA Study

open access: yesEuropean Journal of Haematology, Volume 116, Issue 2, Page 185-194, February 2026.
ABSTRACT Introduction Perceptions and experiences of shared decision‐making between patients and physicians in multiple myeloma (MM) care are not fully understood. A survey study was conducted to explore these perspectives in Spain. Methods Two anonymous online surveys, one for haematologists and one for MM patients, were developed.
Valentín Cabañas   +5 more
wiley   +1 more source

Descarte de bolsas de sangue devido à reatividade para doença de Chagas em um laboratório de triagem sorológica de doadores em Porto Alegre-RS Disposal of blood units due to reactivity for Chagas' disease in a blood donor serological screening laboratory in Porto Alegre, Brazil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2009
A transmissão transfusional (DCT) da doença de Chagas foi aventada nos anos 30 e comprovada nos anos 50. Inicialmente a sorologia pré-transfusional não era obrigatória e nas décadas seguintes os testes foram aperfeiçoados com técnicas mais adaptadas e ...
Douglas B. Fitarelli, Joel F. Horn
doaj  

HLA‐DRB1 Allelic Combinations Differentially Shape Dendritic Cell Antigen Presentation Enhanced by Tumour Cell Line Lysate‐Pulsing

open access: yesHLA, Volume 107, Issue 2, February 2026.
ABSTRACT The anti‐tumour immune response plays a pivotal role in eliminating tumour cells, with the presence of tumour‐infiltrating lymphocytes (TILs) often correlated with improved patient outcomes. Among these, CD4+ T lymphocytes act as key orchestrators of the immune response, functioning as effector and regulatory cells, and are essential for ...
Gonzalo Lázaro   +9 more
wiley   +1 more source

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