Results 111 to 120 of about 1,039,599 (349)

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

Incidence and influencing factors of accidents among the elderly in Henan province

open access: yesHuli yanjiu, 2023
ObjectiveTo investigate the incidence and influencing factors of accidents among the elderly in Henan province.Methods6 054 elderly people aged ≥60 years in Henan province were selected by stratified multi⁃stage cluster random sampling,the incidence of ...
ZHANG Han   +7 more
doaj  

Regional innovation and spillover effects of foreign direct investment in China: a threshold approach [PDF]

open access: yes, 2012
Using a data set on twenty-nine Chinese provinces for the period 1985–2008, this paper establishes a threshold model to analyse the relationship between spillover effects of foreign direct investment (FDI) and regional innovation in China. There is clear
Acs Z.   +38 more
core   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

open access: yesAdvanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian   +13 more
wiley   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

open access: yesAdvanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji   +10 more
wiley   +1 more source

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

open access: yesAdvanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu   +23 more
wiley   +1 more source

Preoperative Central Sensitization in Pilon Fracture Outcomes: Considerations on Grouping, Analgesia, and Data Interpretation [Letter]

open access: yesJournal of Pain Research
Bohui Gao Henan University of Chinese Medicine, Zhengzhou, Henan Province, People’s Republic of ChinaCorrespondence: Bohui Gao, Henan University of Chinese Medicine, Zhengzhou, Henan Province, People’s Republic of China, Tel +1 860 ...
Gao B
doaj  

Evaluation and source identification of water pollution

open access: yesEcotoxicology and Environmental Safety
Maintaining good surface water quality is essential for protecting ecosystems and human health. Henan Province has long faced challenges related to water scarcity and severe water pollution.
Huaibin Wei   +5 more
doaj   +1 more source

Competitive Pressure on China: Factor Rewards Migration [PDF]

open access: yes
Our objective is to assess personal income under perfect competition, when factors are rewarded according to their productivities, and to contrast the ensuing distribution with the status quo.Competition will yield winners and losers, both in terms of ...
Pan, H., Raa, T. ten
core   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

open access: yesAdvanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu   +11 more
wiley   +1 more source

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