Results 131 to 140 of about 974,195 (308)

Henan province (China), man with cart passing carved stone turtles along road

open access: yes, 1913
Turtle tablets by roadside near Ling-pau-hs, Honan [Henan province].GrayscaleClapp Nitrate Negatives, Box
Clapp, Frederick G. (Frederick Gardner), 1879-1944
core  

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

open access: yesAdvanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge   +13 more
wiley   +1 more source

A note on Corydalis in Henan, China [PDF]

open access: yes
[Objective] This study aims to examine the species diversity of the genus Corydalis in Henan, China, and to further identify species distribution. [Methods] After reviewing the literatures and specimens from the Chinese Virtual Herbarium (CVH), we ...
SU Jing   +5 more
core   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

open access: yesAdvanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi   +16 more
wiley   +1 more source

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

open access: yesAdvanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi   +6 more
wiley   +1 more source

Association Between Inflammatory Biomarkers and Cognitive Dysfunction Analyzed by MRI in Diabetes Patients

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2020
Xue Yang, 1,* Yiqi Chen, 2,* Wenshuo Zhang, 3 Zhen Zhang, 4 Xueli Yang, 2 Pengxu Wang, 2 Huijuan Yuan 2 1Department of Education and Training, Diabetes Research Center, Henan Province People’s Hospital, Zhengzhou, Henan Province, People’s ...
Yang X   +6 more
doaj  

Unlocking Li/Mg‐Based Photochemical Nitration Platforms for Anticancer Drug Discovery

open access: yesAdvanced Science, EarlyView.
Two low‐toxicity light main‐group metal photochemical systems based on lithium and magnesium are constructed for selective C(sp2)‐H (di)nitration of anilines. The obtained dinitrated products exhibit anti‐HCC (hepatocellular carcinoma) and anti‐KYSE30 cell activities, holding promise as novel antitumor candidates.
Qian Wan   +13 more
wiley   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

open access: yesAdvanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu   +10 more
wiley   +1 more source

Predicting Freeway Pavement Construction Cost Using a Back-Propagation Neural Network: a Case Study in Henan, China

open access: yes, 2014
The objective of this research was to develop a model to estimate future freeway pavement construction costs in Henan Province, China. A comprehensive set of factors contributing to the cost of freeway pavement construction were included in the model ...
He, Jie   +9 more
core   +1 more source

MN•CS•IO System: Cross‐Species Study for HBB Function in High‐Altitude Hypoxia Adaptation

open access: yesAdvanced Science, EarlyView.
We developed an integrative mesh‐nanorod sorting, chitosan nanoparticle delivery, and intraosseous injection (MN•CS•IO) system to investigate HBB in high‐altitude hypoxia adaptation. Transplanting Tibetan animals' HBB‐modified Lin‐ cells into mice achieved 95.59% transfection efficiency and 8.15% HBB expression. High‐altitude HBB recipients upregulated
Wenqiao Hui   +18 more
wiley   +1 more source

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