Results 161 to 170 of about 974,195 (308)

A Study on Urban Tourism Competitiveness of Henan Province [PDF]

open access: yes, 2012
According to the principle of science, system, pertinency and hierarchy, combining the availability of the evaluation data, this paper establishes the urban competitiveness evaluation system, analyzes the tourism competitiveness of 18 regions in Henan ...
Sun, Xin, Zhuang, Xiaoli
core  

pH‐Responsive Nanoplatform‐Mediated Lipid Hijacking and Metabolic Collapse for Synergistic Starvation‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pH‐responsive ZIF‐8/2‐DG@Cu‐TA nanoplatform orchestrates multifaceted metabolic disruption for synergistic starvation‐immunotherapy. Acid‐triggered 2‐DG release blocks glycolysis, while Zn2+ overload induces mitochondrial dysfunction. Concurrently, Cx43‐mediated gap junctions redirect lipid droplets from tumor cells to cancer‐associated fibroblasts ...
Xianlong Zong   +9 more
wiley   +1 more source

A Predictive Model for Pulmonary Aspergillosis in ICU Patients: A Multicenter Retrospective Cohort Study

open access: yesInfection and Drug Resistance
Yujing Li,1,2,* Xindie Ren,3,* Qianqian Wang,4,* Songying Shen,2,* Yihao Li,1,2 Xinling Qian,2 Yufei Tang,2 Jinguang Jia,2 Hao Zhang,2 Junjie Ding,2 Yinsen Song,1 Sisen Zhang,1 Shengfeng Wang,5 Yinghe Xu,6 Yongpo Jiang,6 Xuwei He,7 Muhua ...
Li Y   +24 more
doaj  

An Integrated Framework Coupling Hierarchical Hyperspectral i‐trait Screening, Gene Identification, and Functional Validation for Genetic Dissection of Salt Tolerance in Cotton

open access: yesAdvanced Science, EarlyView.
An integrated phenomics–genomics framework captures dynamic salt‐stress responses in laboratory‐grown cotton seedlings through time‐series hyperspectral imaging and non‐destructive i‐trait extraction. Hierarchical screening identifies biologically relevant, heritable, and non‐redundant traits for high‐resolution GWAS, identifying GhST7.
Bowei Xu   +11 more
wiley   +1 more source

Loss of Lepr in Fibroblasts Drives Tumor Development by Promoting Macrophage Infiltration

open access: yesAdvanced Science, EarlyView.
TNFα and TGFβ signaling reprograms Lepr+ fibroblasts toward a LeprnegMmphigh inflammatory CAF (iCAF) state, with downregulation of the Tcf21‐Lepr axis contributing to this transition. Lepr loss induces Csf3, which contributes to the enhanced macrophage‐recruiting capacity of these iCAFs, thereby promoting tumor development. Thus, inflammatory signaling
Manyu Song   +13 more
wiley   +1 more source

A Qualitative Study on the Supportive Care Needs Preferences of Older Colorectal Cancer Patients: Insights from Patient Experiences

open access: yesPatient Preference and Adherence
Xiaowan Li,1,* Luqing Wu,2,* Mengqi Zhang,3,* Liqun Yao,4,* Na Zhou,1 You Li,5 Xinying Song,6 Huiyue Zhou,1 Anni Song,1 Jiao Zhou1 1Nursing Department, Ninth People’s Hospital of Zhengzhou, Zhengzhou, Henan Province, 450053, People’s ...
Li X   +9 more
doaj  

Single‐Cell Insights Into Pathogenic Profile of Orchitis and SREBP2‐Associated Cholesterol Dysregulation in Spermatogenic Failure

open access: yesAdvanced Science, EarlyView.
A first single‐cell atlas of human orchitis reveals coordinated germ‐cell loss, somatic niche dysfunction, and immune‐metabolic remodeling. Aberrant SREBP2 activation in testicular somatic cells emerges as a central pathogenic node, while Fatostatin‐mediated inhibition of the SREBP pathway improves spermatogenesis, fibrosis, and lipid accumulation in a
Yanlin Tang   +16 more
wiley   +1 more source

Chemical Rounding Suppresses Morphology‐Induced Interfacial Losses in Perovskite–Silicon Tandem Solar Cells

open access: yesAdvanced Energy Materials, EarlyView.
Chemical rounding transforms irregular submicron silicon textures into more favorable interfaces for perovskite–silicon tandems. Suppressed local epitaxial ordering improves bottom‐cell passivation, while the top‐cell stack exhibits a higher and more spatially uniform quasi‐Fermi‐level splitting, enabling monolithic tandem solar cells with an ...
Nan Sun   +12 more
wiley   +1 more source

Methanol Decomposition on TiO2 Under Ambient Conditions: Cooperative Proton Transfer at Hydrated Interfaces

open access: yesAngewandte Chemie International Edition, EarlyView.
Under ambient conditions, the TiO2 surface becomes hydrated by adsorbed hydroxyl groups (OH) and water molecules. This surface hydration promotes methanol decomposition, rendering the first deprotonation step nearly barrierless compared with ideal UHV conditions.
Milad Salarinasab   +12 more
wiley   +1 more source

Type C Personality and Depression Among Newly Diagnosed Breast Cancer Patients: The Mediating Role of Sense of Coherence

open access: yesNeuropsychiatric Disease and Treatment, 2019
Miao Wei,1 Lina Guo,1 Yiru Zhu,1 Yvru Guo,2 Suyuan Yv,1 Genoosha Namassevayam,1 Wenhua Xue,3 Jieyao Li,4 Lifeng Li,4 Zhibo Shen,4 Junlin Yv,4 Zijia Zhu,3 Wenbin Wang,3 Yanjin Liu,5 Jie Zhao,3 Fu Chen6 1Department of Neurology, The First Affiliated ...
Wei M   +15 more
doaj  

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