Hendra virus infection dynamics in Australian fruit bats. [PDF]
Hendra virus is a recently emerged zoonotic agent in Australia. Since first described in 1994, the virus has spilled from its wildlife reservoir (pteropid fruit bats, or 'flying foxes') on multiple occasions causing equine and human fatalities.
Hume Field +8 more
doaj +11 more sources
Novel Hendra Virus Variant Circulating in Black Flying Foxes and Grey-Headed Flying Foxes, Australia [PDF]
A novel Hendra virus variant, genotype 2, was recently discovered in a horse that died after acute illness and in Pteropus flying fox tissues in Australia.
Alison J. Peel +13 more
doaj +3 more sources
Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology. [PDF]
Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Crowley DE +24 more
europepmc +3 more sources
Hendra virus and horse owners--risk perception and management. [PDF]
Hendra virus is a highly pathogenic novel paramyxovirus causing sporadic fatal infection in horses and humans in Australia. Species of fruit-bats (genus Pteropus), commonly known as flying-foxes, are the natural host of the virus.
Nina Kung +5 more
doaj +6 more sources
Hendra virus is a zoonotic paramyxovirus, which causes severe respiratory and neurological disease in horses and humans. Since 2012, the Hendra virus sub-unit G vaccine has been available for horse vaccination in Australia. Uptake of the vaccine has been
Kailiea Arianna Goyen +3 more
doaj +3 more sources
Aggregated Hendra virus C-protein activates the NLRP3 inflammasome to induce inflammation [PDF]
Background Hendra virus is an emerging virus with a geographically broad host reservoir. In humans, Hendra virus causes excessive inflammatory disease of the lung and nervous system. Our current understanding as to how Hendra virus or what factors induce
Kristian Barry +4 more
doaj +2 more sources
A single dose investigational subunit vaccine for human use against Nipah virus and Hendra virus [PDF]
Nipah and Hendra viruses are highly pathogenic bat-borne paramyxoviruses recently included in the WHO Blueprint priority diseases list. A fully registered horse anti-Hendra virus subunit vaccine has been in use in Australia since 2012.
Thomas W. Geisbert +11 more
doaj +2 more sources
Sero-Monitoring of Horses Demonstrates the Equivac® HeV Hendra Virus Vaccine to Be Highly Effective in Inducing Neutralising Antibody Titres [PDF]
Hendra virus (HeV) is a high consequence zoonotic pathogen found in Australia. The HeV vaccine was developed for use in horses and provides a One Health solution to the prevention of human disease.
Kim Halpin +2 more
doaj +2 more sources
Repurposing FDA-Approved Drugs as Hendra Virus RNA-Dependent RNA Polymerase Inhibitors: A Comprehensive Computational Drug Discovery Approach [PDF]
Hendra virus (HeV) is a highly pathogenic zoonotic paramyxovirus that poses a serious threat to human and equine health, yet no approved antivirals or vaccines currently exist. RNA-dependent RNA polymerase (RdRp) of Hendra virus represents a critical and
Anjana C. Lalu +7 more
doaj +2 more sources
Hendra virus: research progress on a bat-borne threat lurking at the human-animal interface [PDF]
Hendra virus (HeV) is a highly lethal zoonotic henipavirus that has caused recurrent cross-species spillover events in Australia since 1994. Its capacity for cross-species spillover, together with its tropism for vascular endothelial and neural tissues ...
Yanqin Duan +7 more
doaj +2 more sources

