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Sero-Monitoring of Horses Demonstrates the Equivac^® HeV Hendra Virus Vaccine to Be Highly Effective in Inducing Neutralising Antibody Titres [PDF]

Vaccines, 2021
Hendra virus (HeV) is a high consequence zoonotic pathogen found in Australia. The HeV vaccine was developed for use in horses and provides a One Health solution to the prevention of human disease.
Kim Halpin, Kerryne Graham, Peter A. Durr   +2 more
doaj   +2 more sources

Repurposing FDA-Approved Drugs as Hendra Virus RNA-Dependent RNA Polymerase Inhibitors: A Comprehensive Computational Drug Discovery Approach [PDF]

Viruses
Hendra virus (HeV) is a highly pathogenic zoonotic paramyxovirus that poses a serious threat to human and equine health, yet no approved antivirals or vaccines currently exist. RNA-dependent RNA polymerase (RdRp) of Hendra virus represents a critical and
Anjana C. Lalu, Varun Thachan Kundil, Bristow Ben Joseph, Radul R. Dev, Amritha Thaikkad, Suhail Subair, Rajesh Raju, Abhithaj Jayanandan   +7 more
doaj   +2 more sources

Hendra in the Hunter Valley

One Health, 2020
In June 2019 the first equine case of Hendra virus in the Hunter Valley, New South Wales, Australia was detected. An urgent human and animal health response took place, involving biosecurity measures, contact tracing, promotion of equine vaccinations and
K.M. Williamson, S. Wheeler, J. Kerr, J. Bennett, P. Freeman, J. Kohlhagen, A.J. Peel, P. Eby, T. Merritt, T. Housen, C. Dalton, D.N. Durrheim, Liam Chirio, Adrienne Dale, Devin Jones, Kirk Silas   +15 more
doaj   +2 more sources

Establishment of a Pseudovirus-Based Golden Hamster Model for the Attachment and Entry Stages of Hendra Virus Infection and Evaluation of Protective Immunity [PDF]

Pathogens
Objective: Establish an in vivo evaluation model focused on the attachment and entry stages of Hendra virus infection for protective immunity assessment. Methods: A golden hamster infection model based on recombinant Hendra-F/G pseudovirus was developed,
Tao Li, Binfan Liao, Danfeng Li, Jie Zhang, Chunhui Zhao, Yunfei Pei, Liping Chen, Meng Wang, Yawen Liu, Xi Wu, Weijin Huang, Jianhui Nie   +11 more
doaj   +2 more sources

Hendra virus infection in a veterinarian [PDF]

Medical Journal of Australia, 2006
A veterinarian became infected with Hendra virus (HeV) after managing a terminally ill horse and performing a limited autopsy with inadequate precautions. Although she was initially only mildly ill, serological tests suggested latent HeV infection. Nevertheless, she remains well 2 years after her initial illness. Recently emerged zoonotic viruses, such
Hanna, J.N., McBride, W.J., Brookes, D.L., Shield, J., Taylor, C.T., Smith, I.L., Craig, S.B., Smith, G.A.   +7 more
openaire   +6 more sources

“Why won’t they just vaccinate?” Horse owner risk perception and uptake of the Hendra virus vaccine

BMC Veterinary Research, 2017
Background Hendra virus is a paramyxovirus that causes periodic serious disease and fatalities in horses and humans in Australia first identified in 1994.
J. Manyweathers, H. Field, N. Longnecker, K. Agho, C. Smith, M. Taylor   +5 more
doaj   +2 more sources

Hendra virus and Nipah virus animal vaccines. [PDF]

Vaccine, 2016
Hendra virus (HeV) and Nipah virus (NiV) are zoonotic viruses that emerged in the mid to late 1990s causing disease outbreaks in livestock and people. HeV appeared in Queensland, Australia in 1994 causing a severe respiratory disease in horses along with a human case fatality. NiV emerged a few years later in Malaysia and Singapore in 1998-1999 causing
Broder CC, Weir DL, Reid PA.
europepmc   +4 more sources

Identifying Hendra virus diversity in pteropid bats. [PDF]

PLoS ONE, 2011
Hendra virus (HeV) causes a zoonotic disease with high mortality that is transmitted to humans from bats of the genus Pteropus (flying foxes) via an intermediary equine host. Factors promoting spillover from bats to horses are uncertain at this time, but
Ina Smith, Alice Broos, Carol de Jong, Anne Zeddeman, Craig Smith, Greg Smith, Fred Moore, Jennifer Barr, Gary Crameri, Glenn Marsh, Mary Tachedjian, Meng Yu, Yu Hsin Kung, Lin-Fa Wang, Hume Field   +14 more
doaj   +6 more sources

Promotion of Hendra Virus Replication by MicroRNA 146a [PDF]

Journal of Virology, 2013
ABSTRACT Hendra virus is a highly pathogenic zoonotic paramyxovirus in the genus Henipavirus . Thirty-nine outbreaks of Hendra virus have been reported since its initial identification in Queensland, Australia, resulting in seven human infections and four fatalities.
Cameron R, Stewart, Glenn A, Marsh, Kristie A, Jenkins, Michael P, Gantier, Mark L, Tizard, Deborah, Middleton, John W, Lowenthal, Jessica, Haining, Leonard, Izzard, Tamara J, Gough, Celine, Deffrasnes, John, Stambas, Rachel, Robinson, Hans G, Heine, Jackie A, Pallister, Adam J, Foord, Andrew G, Bean, Lin-Fa, Wang   +17 more
openaire   +3 more sources

Flying-fox species density--a spatial risk factor for Hendra virus infection in horses in eastern Australia. [PDF]

PLoS ONE, 2014
Hendra virus causes sporadic but typically fatal infection in horses and humans in eastern Australia. Fruit-bats of the genus Pteropus (commonly known as flying-foxes) are the natural host of the virus, and the putative source of infection in horses ...
Craig Smith, Chris Skelly, Nina Kung, Billie Roberts, Hume Field   +4 more
doaj   +3 more sources