Results 121 to 130 of about 5,816 (198)

Inhibition of Henipavirus infection by RNA interference

open access: yesAntiviral Research, 2008
Nipah virus (NiV) and Hendra virus (HeV) are recently emerged zoonotic paramyxoviruses exclusively grouped within a new genus, Henipavirus. These viruses cause fatal disease in a wide range of species, including humans. Both NiV and HeV have continued to re-emerge sporadically in Bangladesh and Australia, respectively.
Mungall, Bruce A.   +3 more
openaire   +2 more sources

Robustness promotes evolvability of thermotolerance in an RNA virus [PDF]

open access: yes, 2008
Background The ability for an evolving population to adapt to a novel environment is achieved through a balance of robustness and evolvability. Robustness is the invariance of phenotype in the face of perturbation and evolvability is the capacity to ...
Turner Paul E   +2 more
core   +2 more sources

A novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro [PDF]

open access: yes, 2017
Background: Zoonotic transmission events play a major role in the emergence of novel diseases. While such events are virtually impossible to predict, wildlife screening for potential emerging pathogens can be a first step.
Dabrowski, Piotr Wojtek   +4 more
core   +2 more sources

Characterization of African bat henipavirus GH-M74a glycoproteins

open access: yesJournal of General Virology, 2014
In recent years, novel henipavirus-related sequences have been identified in bats in Africa. To evaluate the potential of African bat henipaviruses to spread in non-bat mammalian cells, we compared the biological functions of the surface glycoproteins G and F of the prototype African henipavirus GH-M74a with those of the glycoproteins of Nipah virus ...
Michael, Weis   +8 more
openaire   +2 more sources

Unraveling the Convoluted Biological Roles of Type I Interferons in Infection and Immunity: A Way Forward for Therapeutics and Vaccine Design

open access: yes, 2016
It has been well-established that type I interferons (IFN-Is) have pleiotropic effects and play an early central role in the control of many acute viral infections.
Ranasinghe, Charani   +2 more
core   +1 more source

Nipah virus: an emerging zoonotic threat with pandemic potential, therapeutic control and vaccine development [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi
Throughout history, viral outbreaks of varying intensities and frequencies have caused disaster and terror in the world. The Nipah virus (NiV), which is extremely virulent, has a high case fatality rate, high pandemic potential, and a contagious virus ...
Muhammad Shoaib MAQBOOL   +6 more
doaj   +1 more source

Sub-Nucleolar Trafficking of Hendra Virus Matrix Protein Is Regulated by Ubiquitination

open access: yesViruses
Hendra virus (HeV) is a highly pathogenic member of the Henipavirus genus (family Paramyxoviridae, order Mononegavirales), for which all basic replication processes are located in the cytoplasm.
Tianyue Zhao   +6 more
doaj   +1 more source

Promotion of Hendra virus replication by microRNA 146a

open access: yes, 2013
Hendra virus is a highly pathogenic zoonotic paramyxovirus in the genus Henipavirus. Thirty-nine outbreaks of Hendra virus have been reported since its initial identification in Queensland, Australia, resulting in seven human infections and four ...
A. G. Bean   +68 more
core   +1 more source

Mission to Indonesia to participate to the 1st Indonesia- France Seminar in Medicine & Public Health and investigate potential collaborations on animal health : 2nd - 9th of November 2012 [PDF]

open access: yes, 2012
Emerging and zoonotic infectious diseases are a major issue in Indonesia. The objective of this mission, funded by the Institut Français d'Indonésie (IFI), was to identify potential subjects of collaboration between CIRAD, Pasteur Institute, and ...
Bourhy, Hervé   +2 more
core  

Zoonoses (Project 1): Wildlife/domestic livestock interactions [PDF]

open access: yes, 2011
The objective of this study was to synthesise the best available scientific knowledge about zoonotic disease transmission through livestock and wildlife interaction (direct or indirect), with emphasis on risk factors, drivers and trajectories of ...
Alonso, Silvia   +11 more
core  

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