Results 31 to 40 of about 9,015 (118)

JAK Inhibitors for Treatment of SAPHO Syndrome: A Systematic Review of 72 Cases

ACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome usually involves bones, joints, and skin. Due to a lack of known pathogenesis and clinical trials, there is no standard treatment of SAPHO syndrome. Because none of the current treatments have a high efficacy and the risk of relapse is high, new treatment options for ...
Patrick Fazeli, Saeed Bahramian, Kimia Farahmand, Hamed Ghoshouni, Yalda Farahmand, Amirali Soheili, Leyla Bagheri, Huria Memari, Aydin Feyzi, Seyed Mohammad Vahabi   +9 more
wiley   +1 more source

Púrpura de Henoch-Schönlein Associada a Adenocarcinoma do Pulmão [PDF]

, 2015
Introduction: The Henoch-Schönlein purpura (HSP) is an immunoglobulin A (IgA)-mediated smallvessel systemic vasculitis, rare in adults. The association with solid tumours has been described, especially with lung cancer. Case Report: We present the case
Azevedo, A, Carvalho, F, Fernandes, V, Ferreira, AC, Navarro, D, Nolasco, F, Sousa, J, Viana, H   +7 more
core  

Essential Thrombocythemia's Role in the Complex Landscape of Vasculitis: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Peripheral gangrenes have been sporadically documented as the initial presentation of essential thrombocythemia (ET), as exemplified in the preceding case reports. Nevertheless, the prevalence of vasculitis‐induced skin problems as the primary indication of ET has not been extensively examined.
Mohammad Reza Jafari Nakhjavani, Seyedeh‐Tarlan Mirzohreh, Sousan Kolahi, Mehrzad Hajialilo, Mehdi Jafarpour, Arezou Ghassembaglou, Mir Ali Sattary Oskouie, Tala Pourlak, Sepideh Tahsini Tekantapeh   +8 more
wiley   +1 more source

The Association of RNase L, Cytokines, and Chemokines With Severity of Multisystem Inflammatory Syndrome in Children

Journal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT The 2′,5′‐oligoadenylate synthetase (OAS)‐ribonuclease L (RNase L) system, induced by type I interferons, defends against RNA viruses. Inborn errors in this pathway may trigger inflammatory cytokines, contributing to SARS‐CoV‐2‐related multisystem inflammatory syndrome in children (MIS‐C).
Ting‐Yu Yen, Chia‐Lang Hsu, Chun‐Yi Lu, Ni‐Chung Lee, Ming‐Tai Lin, Kuan‐Ying Arthur Huang, Boon Fatt Tan, Tu‐Hsuan Chang, Chun‐Min Kang, Wei‐Shiung Yang, Bor‐Luen Chiang, Li‐Min Huang, Hsin‐Hui Yu, Luan‐Yin Chang   +13 more
wiley   +1 more source

IgA Vasculitis Across the Ages: Is It Time for a Precision Medicine Approach?

ACR Open Rheumatology, Volume 7, Issue 9, September 2025.
IgA vasculitis (IgAV; formerly Henoch‐Schönlein purpura) is a systemic small vessel vasculitis most commonly affecting the skin, gut, joints, and kidneys. Nephritis is the most concerning complication for all ages because it carries the risk of progression to irreversible end‐stage kidney failure.
A. Gage, R. J. Pepper, J. Marro, A. D. Salama, L. Oni   +4 more
wiley   +1 more source

Púrpura de Schönlein Henoch. A propòsit d'un cas en una esportista [PDF]

, 2006
Presentem el cas d'una esportista de natació sincronitzada de 15 anys amb púrpura de Schönlein-Henoch (també coneguda per púrpura anafilactoide), una vasculitis sistèmica de petits vasos, considerada la més freqüent en la infància, i que afecta ...
Balius Matas, Ramon, Escoda Mora, Jaume, Estruch Massana, Assumpta, Gutiérrez Rincón, Josep, Pifarré San Agustín, Fernando   +4 more
core  

Acute Post‐Streptococcal Glomerulonephritis in a 22‐Month‐Old Toddler: A Rare and Uncustomary Age of Onset

Clinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT Acute post‐streptococcal glomerulonephritis (APSGN) is an important immunological complication that follows Group A Streptococcus (GAS) infections. It usually affects children between 5 and 15 years of age and is rarely seen in children younger than 3 years, likely because their immature immune systems limit the exaggerated immune response ...
Abrham Bire Akeberegn, Amanuel Anegagregn Bizuneh   +1 more
wiley   +1 more source

Adverse Event Profiles Following Human Papillomavirus Vaccination in Males

iMetaMed, Volume 1, Issue 1, September 2025.
Adverse event reports following Gardasil and Gardasil 9 vaccination in male recipients were extracted from the Vaccine Adverse Event Reporting System database. Multiple disproportionality analysis methods identified positive signals and potential adverse events.
Tianqi Chang, Zhan Zeng, Chenyang Pei, Pengpeng Ye, Lin Liu, Xian Shao, Jingyu Wang   +6 more
wiley   +1 more source

Immune Thrombocytopenia in Finnish Children and Adolescents: A Population‐Based Cohort Study

Acta Paediatrica, Volume 114, Issue 9, Page 2211-2218, September 2025.
ABSTRACT Aim Immune thrombocytopenia (ITP) is the most common cause of thrombocytopenia in children. This study aimed to describe the diagnostics, patient characteristics, and treatment strategies regarding children with ITP, as well as identify risk factors for chronic disease.
Lauri‐Matti Kulmala, Henri Aarnivala, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Riitta Niinimäki   +7 more
wiley   +1 more source

Helicobacter pylori infection: New pathogenetic and clinical aspects [PDF]

, 2014
Helicobacter pylori (H. pylori) infects more than half of the world’s human population, but only 1% to 3% of infected people consequently develop gastric adenocarcinomas. The clinical outcome of the infection is determined by host genetic predisposition,
Hagymási, Krisztina, Tulassay, Zsolt
core   +1 more source