Results 51 to 60 of about 9,673 (180)

Successful Treatment of Severe Purpura Fulminans With Anakinra

open access: yesPediatric Dermatology, Volume 43, Issue 2, Page 421-424, March/April 2026.
ABSTRACT Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities.
Francesco Zulian   +4 more
wiley   +1 more source

Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children. [PDF]

open access: yes, 2016
IMPORTANCE: Because clinical features do not reliably distinguish bacterial from viral infection, many children worldwide receive unnecessary antibiotic treatment, while bacterial infection is missed in others.
Barendregt, Anouk M   +23 more
core   +1 more source

Risk Factors of Disease Progression in IgA Nephropathy: A Systematic Review and Meta‐Analysis

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Objective IgA nephropathy (IgAN) is an important cause of chronic renal failure, and nearly all patients with IgAN are at risk of developing to end‐stage renal disease (ESRD) during their lifetime. This meta‐analysis aimed to identify and evaluate risk factors associated with the progression of IgAN patients.
Dan Xu   +4 more
wiley   +1 more source

Henoch-Schonlein Purpura (HSP)

open access: yesKeluwih, 2019
—Henoch-Schonlein purpura (HSP) is a systemic vasculitic disease (vascular inflammation) characterized by the deposition of immune complexes consisting of IgA in kidney skin.
Lucia Pudyastuti Retnaningtyas
doaj   +1 more source

Therapeutic advances in the treatment of vasculitis [PDF]

open access: yes, 2016
Considerable therapeutic advances for the treatment of vasculitis of the young have been made in the past 10 years, including the development of outcome measures that facilitate clinical trial design.
Brogan, PA, Eleftheriou, D
core   +2 more sources

New‐onset autoimmune disease following SARS‐CoV‐2 infection and mRNA vaccination in Norway: A retrospective cohort study

open access: yesJournal of Internal Medicine, Volume 299, Issue 2, Page 271-282, February 2026.
Abstract Background Studies suggest an increase in autoimmune diseases following SARS‐CoV‐2 infection and/or COVID‐19‐vaccination. We aimed to describe possible associations in Norway. Methods We used information from the emergency preparedness register for COVID‐19, BeredtC19, for all residents aged 18–64 (N = 3,450,080).
Håkon Bøås   +4 more
wiley   +1 more source

Aggregation‐induced emission luminogens in in vitro diagnostics: Advancing biomarker detection in body fluids

open access: yesInterdisciplinary Medicine, Volume 4, Issue 1, January 2026.
This review systematically summarizes recent advances in aggregation‐induced emission (AIE) materials for in vitro diagnostics (IVD). It highlights probe design strategies—categorizing them into direct‐responsive, indirect‐responsive, and nano‐immunoprobes—and their applications in detecting a wide range of biomarkers across diverse body fluids ...
Qi Liu   +5 more
wiley   +1 more source

Hemorrhagic Intestinal Henoch-Schonlein Purpura Complicated by Cytomegalovirus Infection

open access: yesCanadian Journal of Gastroenterology, 1998
A 54-year-old man on hemodialysis for acute chronic renal failure and on corticosteroids for Henoch-Schonlein purpura developed massive hematochezia. After extensive clinical investigation, an ileal bleeding site was identified and surgically removed ...
Phong Nguyen-Ho   +2 more
doaj   +1 more source

A case of IgG4-related tubulointerstitial nephritis concurrent with Henoch-Schönlein purpura nephritis [PDF]

open access: yes, 2011
We describe a 72-year-old man, who had been suffered from Henoch-Schönlein purpura (HSP) several times, presented with hematoproteinuria with granular cast, and general lymphadenopathy.
Rukako Tamai   +5 more
core   +1 more source

Comprehensive multi‐omics mapping of immune perturbations in autism spectrum disorder

open access: yesClinical and Translational Medicine, Volume 15, Issue 12, December 2025.
• Integrated multi‐omics profiling reveals systemic immune dysregulation in ASD, marked by an expansion of atypical immune cell subsets and activation of immune‐related pathways. • Significant alterations in peripheral immune cell populations are observed, including dysregulated NK cells, expanded CD56+ monocytes, and elevated MDSCs, and these changes ...
Chun Yan   +12 more
wiley   +1 more source

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