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Seminars in Immunopathology, 2021 IgA vasculitis (IgAV) is an inflammation of small vessels caused by perivascular deposition of IgA and activation of neutrophils. It may present as systemic vasculitis (IgAV - Henoch-Schönlein purpura) or as a variant restricted to the skin (skin-limited IgAV), while IgA nephropathy presents a variant restricted to the kidneys.
Evangeline Pillebout +2 more
exaly +5 more sources
Pediatric Health, Medicine and Therapeutics, 2023 IgA vasculitis (IgAV) or Henoch-Schönlein purpura (HSP) is the most common vasculitis in children, and nephritis (IgAVN or HSPN) is the most important and only chronic manifestation of the disease.
Mario Sestan, Marija Jelusic
exaly +2 more sources
Pathogenesis of IgA Vasculitis: An Up-To-Date Review
Frontiers in Immunology, 2021 Immunoglobin A (IgA) vasculitis (IgAV), formerly called the Henoch-Schönlein purpura (HSP), is a small vessel vasculitis, characterized by IgA1-dominant immune deposition at diseased vessel walls.
Xiaohan Huang +2 more
exaly +2 more sources
Efficacy and safety of telitacicept in children with IgA vasculitis and IgA vasculitis nephritis: a single-center retrospective study. [PDF]
Pediatr Rheumatol Online JImmunoglobulin A vasculitis (IgAV) is the most common childhood vasculitis and can lead to immunoglobulin A vasculitis nephritis (IgAVN) in severe cases, potentially progressing to kidney failure in a subset of children.
Ma X +7 more
europepmc +2 more sources
IgA nephropathy with leucocytoclastic vasculitis [PDF]
Journal of International Medical Research, 2018 Leucocytoclastic vasculitis is a rare type of allergic disease caused by immune complexes. IgA nephropathy is a glomerulopathy characterized by recurrent episodes of gross haematuria or microscopic haematuria and IgA deposition in the glomerular ...
Lin-Yan Wei +3 more
doaj +3 more sources
Frontiers in Cellular and Infection Microbiology, 2022 ObjectiveTo explore the common differential flora of IgAN, Kawasaki disease and IgA vasculitis by screening and analyzing the differential intestinal flora between the three disease groups of IgAN, Kawasaki disease and IgA vasculitis and their healthy ...
Xueli Hu, Wenzhu Song, Jianbo Qing
exaly +3 more sources
Frontiers in Immunology, 2023 Background IgA vasculitis (IgAV) is an immune-associated vasculitis, yet its exact etiology remains unclear. Here, we explore the interaction between IgAV and inflammatory factors using bidirectional Mendelian randomization (MR).
Chenghao Jin +2 more
exaly +2 more sources
Vaccines, 2022 IgA vasculitis is an immune complex-mediated small-vessel vasculitis that mainly occurs in children and is characterized by palpable purpura, arthralgia, abdominal pain, and glomerulonephritis.
Chang Hun Lee, Kyoung Min Kim
exaly +3 more sources
Frontiers in Pediatrics, 2022 What are the challenges ahead and how have we responded so far when it comes to the non-granulomatous systemic vasculitis, characterized mainly by deposits of IgA immune complexes in the endothelium of small blood vessels—IgA vasculitis (IgAV)?
Marija Jelusic +2 more
exaly +2 more sources
Efficacy of Telitacicept in treating IgA vasculitis nephritis: a two-case report
Frontiers in ImmunologyTelitacicept, a B lymphocyte stimulator/A proliferation-inducing ligand dual-target fusion protein, mainly used for IgA nephropathy and systemic lupus erythematosus.
Shuang-xi Li +6 more
doaj +2 more sources