Results 1 to 10 of about 28,785 (230)

An Exceptional Case of Crohn-Associated IgA-Mediated Goodpasture Disease [PDF]

Kidney Medicine
Anti-glomerular basement membrane (anti-GBM) disease is typically mediated by IgG autoantibodies and presents with pulmonary hemorrhage and rapidly progressive glomerulonephritis, classically referred to as Goodpasture disease.
Rebecca Ryan, Thomas Fairhead, Sophie Seager, Mona Jain, Rauri Clark   +4 more
doaj   +2 more sources

IgA-Nephropathie: Die häufigste Glomerulonephritis-Form [PDF]

Der Nephrologe, 2018
Zusammenfassung: Die IgA-Nephropathie (IgAN) ist die weltweit häufigste primäre Glomerulopathie. Meist manifestiert sie sich in der Adoleszenz oder im frühen Erwachsenenalter als wiederkehrende Makrohämaturie (oft getriggert durch einen Infekt der oberen
Ambühl, P., Corsenca, A.
core   +3 more sources

IgA nephropathy with monotypic IgA-κ deposits: a case report and literature review [PDF]

Frontiers in Medicine
IgA nephropathy (IgAN) is an immune complex-mediated glomerulonephritis characterized by predominant IgA deposition in the mesangial region, typically exhibiting polyclonal IgA deposits (co-dominance of κ and λ light chains).
Xiao-Ying Li, Guang-Liang Xie, Bo Chen, Ji Zhang, Jian-Sheng Chen, Xiao-Kai Ding   +5 more
doaj   +2 more sources

Clinicopathological and prognostic study of IgA-dominant postinfectious glomerulonephritis

BMC Nephrology, 2021
Background The clinicopathological and prognostic features of IgA-dominant postinfectious glomerulonephritis and its difference from the primary IgA nephropathy remains to be investigated.
Ziyuan Huang, Bo Chen, Ying Zhou, Yan Liang, Wenxian Qiu, Yinqiu Lv, Xiaokai Ding, Ji Zhang, Chaosheng Chen   +8 more
doaj   +1 more source

Increased retinal drusen in IgA glomerulonephritis are further evidence for complement activation in disease pathogenesis

Scientific Reports, 2022
Drusen are retinal deposits comprising cell debris, immune material and complement that are characteristic of macular degeneration but also found in glomerulonephritis.
P. Harraka, Tony Wightman, Sarah Akom, Kieran Sandhu, Deb Colville, Andrew Catran, David Langsford, Timothy Pianta, David Barit, Frank Ierino, Alison Skene, Heather Mack, Judy Savige   +12 more
doaj   +1 more source

Hansen's disease with lepra reaction presenting with IgA dominant infection related glomerulonephritis

Indian Journal of Pathology and Microbiology, 2020
Various renal abnormalities in leprosy have been described largely in literature but the occurrence of IgA dominant infection related glomerulonephritis in leprosy with type 2 lepra reaction has not been reported so far. We present here a 60-year-old man
Elayaperumal Indhumathi, Jeyachandran Dhanapriya, Thanigachalam Dineshkumar, Ramanathan Sakthirajan, Natarajan Gopalakrishnan   +4 more
doaj   +1 more source

IgA Vasculitis and C3 Glomerulonephritis: One Patient... Various Autoimmune Diseases

Gazeta Médica, 2022
Leucocytoclastic vasculitis refers to a small vessel vasculitis caused by immune complexes, infections and medications. IgA or IgM/IgG immune complexes can be found in direct immunofluorescence studies suggesting specific forms of leucocytoclastic ...
Ana Margarida Pedro Antunes Ferreira Gaudêncio, Ana Catarina Lameiras, Teresa Mendonça   +2 more
doaj   +4 more sources

Glomerular galactose-deficient IgA1 expression analysis in pediatric patients with glomerular diseases

Scientific Reports, 2020
Galactose-deficient IgA1 (Gd-IgA1) is important in the pathogenesis of IgA nephropathy (IgAN). A Gd-IgA1-specific monoclonal antibody (KM55) has revealed glomerular Gd-IgA1 deposition solely in patients with IgAN and IgA vasculitis with nephritis (IgAV-N)
Shinya Ishiko, Tomoko Horinouchi, Rika Fujimaru, Yuko Shima, Hiroshi Kaito, Ryojiro Tanaka, Shingo Ishimori, Atsushi Kondo, Sadayuki Nagai, Yuya Aoto, Nana Sakakibara, China Nagano, Tomohiko Yamamura, Momoka Yoshimura, Koichi Nakanishi, Junya Fujimura, Naohiro Kamiyoshi, Hiroaki Nagase, Norishige Yoshikawa, Kazumoto Iijima, Kandai Nozu   +20 more
doaj   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

Metabolic Syndrome in IgA Glomerulonephritis [PDF]

Nephron Extra, 2014
<b><i>Background/Aims:</i></b> Metabolic syndrome (MetS) may have an independent impact on the development of chronic kidney disease. This study examines the prevalence of MetS in subjects with IgA glomerulonephritis (IgAGN) and its impact on disease progression in a retrospective fashion. <b><i>Patients and Methods:&
Kaartinen, Kati, Syrjänen, Jaana, Pörsti, Ilkka, Harmoinen, Aimo, Huhtala, Heini, Mustonen, Jukka   +5 more
openaire   +2 more sources