Results 41 to 50 of about 112,745 (226)

InvenioRDM GitHub Archiver (IGA) – Release 1.0.3

, 2023
Changes in this release: The sample workflow has been revised to be slightly more informative about where it's sending the release for archiving.Additional information is available at https://github.com/caltechlibrary/iga/blob/main/CHANGES.mdThe ...
Hucka, Michael
core   +1 more source

InvenioRDM GitHub Archiver (IGA) – Release 1.2.1

, 2023
Changes in this release: Fixed setup.cfg, which had some garbled content. Fixed the GitHub Action for building the IGA documentation pages to avoid needlessly running it on every push.
Hucka, Michael
core   +1 more source

CASTOR1 regulates humoral immune responses and contributes to the pathogenesis of systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objectives CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. Methods We analyzed human B cell transcriptomes from healthy controls and patients with systemic lupus erythematosus (SLE) via ...
Takeshi Kusuda, Toshihiko Komai, Takahiro Itamiya, Tatsuki Abe, Tomohisa Okamura, Keishi Fujio   +5 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Induction of IgA Deposits and Glomerulonephritis by IgA Rheumatoid Factor [PDF]

Journal of the American Society of Nephrology, 2012
In this issue of JASN, Otani et al.1 describe an interesting murine model for studies of IgA-associated GN. The authors explore the nephritogenic potential of two different monoclonal IgA rheumatoid factors (designated as 6-19 IgA and 46-42 IgA) specific for murine IgG2a in relation to potential differences in glycosylation of these IgA antibodies ...
openaire   +2 more sources

Inflammatory Bowel Disease Is Associated With an Increased Risk of End‐Stage Renal Disease: A Population‐Based Cohort Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a retrospective population‐based cohort study using the University of Manitoba IBD Epidemiology Database, persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD ...
Onuma Sattayalertyanyong, Zoann Nugent, Bryce Barr, Keevin N. Bernstein, Charles N. Bernstein   +4 more
wiley   +1 more source

Insulin resistance and the progression of IgA glomerulonephritis [PDF]

Nephrology Dialysis Transplantation, 2007
IgA glomerulonephritis (IgAGN) has a highly variable prognosis with 15-40% of patients progressing to end-stage renal disease. Hypertension, proteinuria and renal insufficiency are risk factors associated with poor prognosis. The role of insulin resistance is unclear in IgAGN.From a retrospective cohort of IgAGN patients, a total of 174 patients (104 ...
Kati, Kaartinen, Jaana, Syrjänen, Ilkka, Pörsti, Aimo, Harmoinen, Amos, Pasternack, Heini, Huhtala, Onni, Niemelä, Jukka, Mustonen   +7 more
openaire   +2 more sources

Rapidly progressive glomerulonephritis due to anti-glomerular basement membrane disease accompanied by IgA nephropathy: An unusual association

Saudi Journal of Kidney Diseases and Transplantation, 2017
Anti-glomerular basement membrane (anti-GBM) disease is a systemic autoimmune disorder characterized by circulating IgG antibodies (rarely IgA and IgM) to the carboxyterminal, noncollagenous 1 (NC1) domain of type IV collagen of GBM also known as ...
Ishwarya Annamalai, G Chandramohan, N D Srinivasa Prasad, Edwin Fernando, S Sujith   +4 more
doaj   +1 more source

Clinicopathologic features of infection-related glomerulonephritis with IgA deposits: a French Nationwide study

Diagnostic Pathology, 2020
Background Infection-related glomerulonephritis with IgA deposits (IRGN-IgA) is a rare disease but it is increasingly reported in the literature. Data regarding epidemiology and outcome are lacking, especially in Europe.
Elodie Miquelestorena-Standley, Charlotte Jaulerry, Marie-Christine Machet, Nolwenn Rabot, Christelle Barbet, Aurélie Hummel, Alexandre Karras, Cyril Garrouste, Thomas Crepin, Didier Ducloux, Maud Cousin, Catherine Albert, Joseph Rivalan, Emilie Cornec-Le Gall, François Pourreau, Clément Deltombe, Dominique Nochy, Nora Szlavik, Sophie Felix, Anne Croué, David Buob, Nathalie Rioux-Leclerc, Laurent Doucet, Jean-Michel Goujon, Karine Renaudin, Emmanuelle Blanchard, Sébastien Eymieux, Marion Rabant, Jean-Michel Halimi   +28 more
doaj   +1 more source

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source