Results 51 to 60 of about 21,254 (226)

Renal extraglomerular vascular immune deposits in IgA glomerulonephritis

, 1992
Renal extraglomerular vascular immune deposits in IgA glomerulonephritis. Kidney biopsies of 425 patients with IgA glomerulonephritis were studied to reveal the incidence, composition and possible clinical significance of extraglomerular vascular immune ...
Volavšek, Metka, Kveder, Rado, Vizjak, Alenka, Ferluga, Dušan, Luzar, Saša, Zidar, Nina   +5 more
core   +1 more source

Highlights of 2025: advances in germinal centers

Immunology &Cell Biology, EarlyView.
Graphical summary of research advances made in 2025 in germinal center (GC) biology. GCB, germinal center B cells; Tfh, T follicular helper cell; APC, antigen‐presenting cell; FDC, follicular dendritic cell; SHM, somatic hypermutation. Created in BioRender. Webb, L. (2026) https://BioRender.com/bn9jx9v.
Louise MC Webb, Michelle A Linterman
wiley   +1 more source

Interleukin-33 Exacerbates IgA Glomerulonephritis in Transgenic Mice Overexpressing B Cell Activating Factor

, 2022
Background: The cytokine IL-33 is an activator of innate lymphoid cells 2 (ILC2s) in innate immunity and allergic inflammation. B cell activating factor (BAFF) plays a central role in B cell proliferation and differentiation, and high levels of this ...
Hu, M., Chung, E.Y.M., Wu, H., Chadban, S.J., McCarthy, H.J., Mackay, F., Wang, Y.M., Harris, D.C.H., Alexander, S.I., Shaw, K., Grey, S.T., Zheng, G., Cao, Q., Zhang, G.Y., Wang, Y.   +14 more
core   +1 more source

Clinical implications of imlifidase interference in antibody screening and transfusion management

Transfusion, EarlyView.
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani, Aiko P. J. de Vries, Arjan Albersen   +2 more
wiley   +1 more source

Incidence of glomerulonephritis in the western part of Switzerland over the last decade

Swiss Medical Weekly, 2020
BACKGROUND Glomerulonephritis is a rare yet serious group of diseases with a high risk of progression to end-stage renal disease. For optimal healthcare planning, detailed epidemiological and demographic data are essential.
Giliane Nanchen, Kevin Schutzbach, Samuel Rotman, Rebecca Winzeler, Patrice Ambühl, Matthieu Halfon, Menno Pruijm   +6 more
doaj   +1 more source

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Complement membrane attack (MAC) in idiopathic IgA-glomerulonephritis

, 1987
Complement membrane attack (MAC) in idiopathic IgA-glomerulonephritis. Antigens of the membrane attack complex of complement (MAC), such as C5, C6, C9 and MAC-related neoantigen(s), were demonstrated in the mesangium of 23 cases with IgA ...
Ritz, Eberhard, Rauterberg, Ernst W., Lieberknecht, Hans–Michael, Wingen, Anne–Margret   +3 more
core   +1 more source

Clinicopathological characteristics and predictors of renal outcomes in diffuse crescentic glomerulonephritis : a retrospective single-center study from Western China

BMC Nephrology
Background The factors influencing diffuse crescentic glomerulonephritis renal survival and prognosis remain uncertain. Additionally, there’s no literature on the clinical outcomes of IgA nephropathy, lupus nephritis, and IgA vasculitis nephritis in type
Shan Wen, Shasha Chen, Yingying Lin, Guisen Li, Ping Zhang, Wei Wang   +5 more
doaj   +1 more source

Biomarkers for Early Detection of Diabetic Kidney Disease in Pediatric and Adolescent Populations: A Narrative Review

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Diabetic nephropathy is among the most critical long‐term complications linked to diabetes, substantially influencing both morbidity and mortality. Although it was once largely associated with adults, diabetic kidney disease (DKD) has now become a leading source of kidney complications among children worldwide.
Iran Malekzadeh, Narges Falsafi, Mohammad Nazemi, Hanie Taherkhani, Mahboube Bahroudi, Asim Abbas, Mastaneh Moghtaderi   +6 more
wiley   +1 more source

A Case of Self-Limiting Crescentic Immunoglobulin A Glomerulonephritis Associated with Sternoclavicular Arthritis

Case Reports in Nephrology and Dialysis, 2018
Immunoglobulin (Ig) A glomerulonephritis (GN) is a heterogeneous disease affected by various factors. Genetic and other factors “hit” DNA, causing IgA malformation and ultimately glomerular injury.
Yoko Fujita, Tomo Suzuki, Wei Han, Shiika Watanabe, Koichi Yahagi, Mayumi Nakata, Takeshi Okamoto, Daisuke Ichikawa, Junki Koike, Yugo Shibagaki   +9 more
doaj   +1 more source