Results 61 to 70 of about 28,785 (230)

T cells, adhesion molecules and modulation of apoptosis in visceral leishmaniasis glomerulonephritis [PDF]

, 2010
Background: Immune complex deposition is the accepted mechanism of pathogenesis of VL glomerulopathy however other immune elements may participate. Further in the present study, no difference was seen between immunoglobulin and C3b deposit intensity in ...
Francisco AL Costa, Maria G Prianti, Teresa C Silva, Silvana MMS Silva, José L Guerra, Hiro Goto   +5 more
core   +2 more sources

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report. [PDF]

, 2013
Background. Infectious diseases seem to be an important and independent risk factor for renal failure, but the underlying mechanism of renal involvement during some kinds of infectious diseases is still unclear, even if the literature data report ...
Falsaperla, Raffaele, Giunta, Leandra, Nunnari, Giuseppe, Pavone, Piero, Rapisarda, Venerando, Spataro, Giuseppina, Velardita, Mario, Vitaliti, Giovanna   +7 more
core   +3 more sources

Changes in the diagnosis of glomerular diseases in east China: a 15-year renal biopsy study

Renal Failure, 2018
Background: There have been some gradual changes in the distribution of renal biopsy pathological diagnoses during recent years. This study aimed to show changes in renal disease prevalence in China by investigating 10 patients diagnosed at our Kidney ...
Qin Zhou, Xin Yang, Meifang Wang, Huiping Wang, Jie Zhao, Yan Bi, Xiayue Wang, Jihong Yao, Ying Chen, Chuan Lin, Xishao Xie, Hong Jiang, Jianghua Chen   +12 more
doaj   +1 more source

PLA2R‐Positive Membranous Nephropathy and AA Amyloidosis in an Ethiopian Patient With Chronic Hepatitis B: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT The coexistence of primary phospholipase A2 receptor positive membranous nephropathy and AA amyloidosis in a patient with chronic hepatitis B is an exceedingly rare triad presenting a profound diagnostic and therapeutic challenge. A 38‐year‐old Ethiopian man with nephrotic syndrome and chronic hepatitis B had dual pathology on renal biopsy ...
Betelhem Abreham, Leja Hamza, Azeb Kebede, Daniel Rebuma Bekele, Zekarias Amdemariam   +4 more
wiley   +1 more source

Origin of poorly galactosylated IgA1 other than mucosa: a viewpoint from a report on patient with IgA vasculitis

Renal Failure
Patients presenting monoclonal gammopathy of renal significance (MGRS) and IgA vasculitis collectively have rarely been reported. This study reports one patient with monoclonal IgA and λ, and with IgA positive-mesangial proliferative glomerulonephritis ...
Manxia Huang, Jian Cao, Yangpu Li, Hua Xu, Manliu Wang, Yihou Zheng, Mumin Shao, Youjia Zeng, Jicheng Lv   +8 more
doaj   +1 more source

Successful treatment of a patient with posttransplant IgA nephropathy with targeted release formulation of budesonide

Saudi Journal of Kidney Diseases and Transplantation, 2020
Recurrence of glomerulonephritis is the third-leading cause of allograft loss. Graft loss due to IgA nephropathy occurs in 10% at 10-year follow-up.
Umesh Lingaraj, Kishan Aralapuram, Sreedhara Chikkanayakanhalli, Akila Vishwanathan, Mahesha Vankalakunti   +4 more
doaj   +1 more source

Secondary immunoglobulin A nephropathy with gross hematuria leading to rapidly progressive glomerulonephritis following severe acute respiratory syndrome coronavirus 2 vaccination: a case report

BMC Nephrology, 2023
Background The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been followed by many reports of the development and relapse of autoimmune diseases associated with SARS-CoV-2 vaccination.
Miyako Fukuda, Tomohiro Kaneko, Takahiro Kawai, Hiromasa Ishii, Akira Shimizu   +4 more
doaj   +1 more source

IgA-Vasculitis vs. IgA-Glomerulonephritis – Analyse von Nierenhistologien

, 2019
Einleitung: Die IgA-Vaskulitis (PSH, Purpura Schönlein-Henoch) betrifft bei Erwachsenen im Gegensatz zu Kindern deutlich häufiger die Nieren. Histologisch stellt sich der renale Befall dem Pathologen als IgA-Nephritis (IgA-GN) dar. Unklar ist, ob sich die histologischen Befunde einer reinen[zum vollständigen Text gelangen Sie über die oben angegebene ...
Bellmann, M, Wadsack, D, Porubsky, S, Bergner, R   +3 more
openaire   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source