Results 61 to 70 of about 21,381 (225)
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang +4 more
wiley +1 more source
Immunoglobulin (Ig) A glomerulonephritis (GN) is a heterogeneous disease affected by various factors. Genetic and other factors “hit” DNA, causing IgA malformation and ultimately glomerular injury.
Yoko Fujita +9 more
doaj +1 more source
Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni +4 more
wiley +1 more source
Necrotic crescentic glomerulonephritis and IGA nephropathy: Lee-Haas classification revisited [PDF]
Capillary necrosis is frequently encountered in most forms of proliferative glomerulonephritis, and varies in severity from only occasional finding to severe form of glomerular vasculitis.
Wael Latif Jabur
core
The long pentraxin PTX3 is synthesized in IgA glomerulonephritis and activates mesangial cells [PDF]
The long pentraxin PTX3 has been recently involved in amplification of the inflammatory reactions and regulation of innate immunity. In the present study we evaluated the expression and role of PTX3 in glomerular inflammation.
BUSSOLATI, BENEDETTA +5 more
core +1 more source
Background: Many children with kidney diseases can be diagnosed and treated without a biopsy. However, biopsy is a valuable method for the diagnostic and prognostic evaluation of children with kidney diseases.
Neşe Özkayın +4 more
doaj +1 more source
ABSTRACT Introduction Recurrent IgA nephropathy (IgAN) after kidney transplantation has been reported in up to 20%–60% of recipients, through incidence varies by surveillance strategy. We aimed to define the incidence and clinical impact of biopsy‐proven recurrence IgAN in a single center cohort.
Pitchamon Inkong +5 more
wiley +1 more source
Simultaneous occurrence of diabetic glomerulosclerosis, IgA nephropathy, crescentic glomerulonephritis, and myeloperoxidase-antineutrophil cytoplasmic antibody seropositivity in a Chinese patient. [PDF]
We report the case of a 72-year-old woman with a long-standing history of diabetes mellitus who presented with heavy proteinuria and rapid deterioration in renal function.
Chan, TM +5 more
core +1 more source
Highlights of 2025: advances in germinal centers
Graphical summary of research advances made in 2025 in germinal center (GC) biology. GCB, germinal center B cells; Tfh, T follicular helper cell; APC, antigen‐presenting cell; FDC, follicular dendritic cell; SHM, somatic hypermutation. Created in BioRender. Webb, L. (2026) https://BioRender.com/bn9jx9v.
Louise MC Webb, Michelle A Linterman
wiley +1 more source
Patients presenting monoclonal gammopathy of renal significance (MGRS) and IgA vasculitis collectively have rarely been reported. This study reports one patient with monoclonal IgA and λ, and with IgA positive-mesangial proliferative glomerulonephritis ...
Manxia Huang +8 more
doaj +1 more source

