Results 71 to 80 of about 112,745 (226)
Persistent Haematuria Is Associated With Reduced Kidney Survival in Primary Podocytopathies
ABSTRACT Aim Haematuria is frequently present in podocytopathies, but its significance and prognostic value are not well described. This study aimed to determine the prevalence and association between persistent haematuria and kidney survival in patients with membranous nephropathy (MN), minimal change disease (MCD) and focal segmental ...
Gabriel Ștefan +3 more
wiley +1 more source
IgA Nephropathy in North West Frontier Province of Pakistan
Background: IgA nephropathy is the most common form of glomerulonephritis in the world. The extent to which IgA nephropathy is diagnosed depends upon the local attitude towards urine testing and renal biopsy.
Mohammad Noor +4 more
doaj
Objectives. This review addresses the microscopic features of immunoglobulin A nephropathy (IgA nephropathy), its prognostic variables in children, and measures to which extent these features and variables differ from adults.
Reem A. Al Zahrani
doaj +1 more source
Clinical implications of imlifidase interference in antibody screening and transfusion management
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani +2 more
wiley +1 more source
NEPHRITOGENIC ACTIVITY OF IgA-BINDING STREPTOCOCCUS PYOGENES: AN EXPERIMENTAL MODEL OF IgA GLOMERULONEPHRITIS [PDF]
The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this purpose, an approach was attempted which was previously successfully applied in rabbits, aiming for induction of post-streptococcal glomerulonephritis (PSGN)
Duplik, N. V. +11 more
core +1 more source
Active immunization with recombinant THSD7A in mice induces autoreactive B cell activation and differentiation into CD138+ antibody‐secreting cells, leading to the production of anti‐THSD7A autoantibodies, glomerular immune injury and proteinuria, characteristic of membranous nephropathy. NDP‐MSH treatment modulates the MITF/IRF4 axis in primed B cells,
Mingzhuo Zhang +4 more
wiley +1 more source
Schistosoma mansoni associated glomerulopathy with IgA mesangial deposits: case report
Introduction: Renal involvement is a severe form of schistosomiasis and occurs in 10% to 15% of patients with the hepatosplenic form of the disease. Nephrotic syndrome is the most common clinical presentation.
Fabiana Oliveira Gonçalves +2 more
doaj +1 more source
Cutaneous IgA Vasculitis in Primary Sjögren Disease: Findings From a Medical Record–Based Review
Objective This study aimed to describe clinical observations of patients presenting with palpable purpura, which is suspected to represent IgA vasculitis (IgAV) based on direct immunofluorescence (DIF), who were ultimately diagnosed with cutaneous vasculitis associated with primary Sjögren disease (SjD).
Shay Brikman +2 more
wiley +1 more source
IgA-Dominant Postinfectious Glomerulonephritis: A New Twist on an Old Disease
IgA-dominant acute postinfectious glomerulonephritis (APIGN) is an increasingly recognized morphologic variant of APIGN, particularly in the elderly. In contrast to classic APIGN, in which there is typically glomerular deposition of IgG and C3 or C3 only,
Vivette D. D’Agati, Samih H. Nasr
core +1 more source
An Exceptional Case of Crohn-Associated IgA-Mediated Goodpasture Disease
Anti-glomerular basement membrane (anti-GBM) disease is typically mediated by IgG autoantibodies and presents with pulmonary hemorrhage and rapidly progressive glomerulonephritis, classically referred to as Goodpasture disease.
Rebecca Ryan +4 more
doaj +1 more source

