Results 61 to 70 of about 8,451 (217)

GloPath: An Entity‐Centric Foundation Model for Glomerular Lesion Assessment and Clinicopathological Insights

Advanced Science, Volume 13, Issue 29, 22 May 2026.
An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He, Jing Li, Tian Guan, Yifei Ma, Zimo Zhao, Yanxia Wang, Hongjing Chen, Yingming Xu, Shuang Ge, Yexing Zhang, Yizhi Wang, Xinrui Chen, Lianghui Zhu, Yiqing Liu, Qingxia Hou, Shuyan Zhao, Xiaoqin Wang, Lili Ma, Peizhen Hu, Qiang Huang, Zihan Wang, Zhiyuan Shen, Junru Cheng, Siqi Zeng, Jiurun Chen, Zhen Song, Chao He, Zhe Wang, Yonghong He   +28 more
wiley   +1 more source

Biologics and Drug‐Induced Immunogenicity: A Case Report of Acquired Hemophilia A Presenting After Immunotherapy

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Acquired hemophilia A is a rare, potentially life‐threatening bleeding disorder caused by autoantibody inhibitors to coagulation factor VIII. We report the case of an 87‐year‐old female who presented with symptomatic bleeding and was subsequently diagnosed with acquired hemophilia A.
Kevin A. Murgas, Sundus Nasim, Stephen Poos, Jules A. Cohen, Anna Andrzejczyk   +4 more
wiley   +1 more source

Detection of Antiphospholipid Antibody in Children With Henoch-Schonlein Purpura and Central Nervous System Involvement [PDF]

, 2012
To explore the mechanisms of central nervous system involvement in children with Henoch-Schonlein purpura, levels of lupus anticoagulant, anticardiolipin antibodies, and anti-beta 2 glycoprotein I antibodies in serum and cerebrospinal fluid were ...
Liu, Ailin, Zhang, Hongwen
core   +1 more source

A POSSIBLE RELATIONSHIP BETWEEN SERUM HOMOCYSTEINE LEVEL AND IgA NEPHROPATHY IN CHILDREN

İstanbul Tıp Fakültesi Dergisi, 2021
Objective: The evidences from experimental and epidemiological studies suggests that elevated serum homocysteine levels may lead to renal injury and may be a significant risk factor for the development of chronic kidney disease. The aim of this study was
Cemile Pehlivanoğlu, Zeynep Nagehan Yürük Yıldırım, Alev Yılmaz, Asuman Gedikbaşı, Nurinisa Karagöz, Nurver Akıncı, Aysel Kıyak, Gül Özçelik, Mesude Yasemin Özlük, Işın Kılıçaslan, Ayşe Ayşim Özağarı, Bağdagül Yavaş Aksu, Sevinç Emre   +12 more
doaj   +1 more source

Telitacicept Combined With Glucocorticoids as Initial Therapy for Moderate IgA Vasculitis Nephritis With Concurrent Pulmonary Infection in Children: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
This graphical abstract depicts the clinical course of a 14‐year‐old male with moderate IgAV‐N treated with telitacicept combined with glucocorticoids as initial therapy. Rapid glucocorticoid tapering, normalized renal function, and continuous remission of proteinuria and hematuria were achieved.
Jiayi Li, Zhao Chen, Jiamei Lu, Pei Zhang, Xiaotao Ma, Xia Yang, Akhmedova Nilufar Sharipovna, Rongguo Fu   +7 more
wiley   +1 more source

Lupus anticoagulant and thrombosis following Henoch-Schonlein purpura. [PDF]

, 2007
A male adolescent developed a sinovenous thrombosis 4 weeks following a Henoch-Schonlein purpura episode. A hypercoagulation evaluation revealed a positive lupus anticoagulant.
Spencer, Charles H, Licht, Daniel J, Abend, Nicholas S   +2 more
core  

Development of a Novel UPC (Urine Red Blood Cell Distribution, Proteinuria, and Serum Creatinine) Index to Differentiate Glomerular from Nonglomerular Hematuria

Journal of Clinical Laboratory Analysis, Volume 40, Issue 8, April 2026.
The study developed the UPC index by integrating urine red blood cell distribution (URD), urine protein strip, and serum creatinine to enhance the diagnostic accuracy for distinguishing glomerular from nonglomerular hematuria. The UPC index demonstrated superior performance (AUC 0.857) compared to conventional parameters, showing high sensitivity and ...
Hae In Bang, Sun Min Lee, In Hee Lee, A‐Jin Lee, Chang‐Ho Jeon   +4 more
wiley   +1 more source

Recurrent adult onset Henoch-Schonlein Purpura: a case report [PDF]

, 2016
Henoch-Schonlein purpura is an immunoglobulin A (IgA)-immune complex mediated leukocytoclastic vasculitis that classically manifests with palpable purpura, abdominal pain, arthritis, and hematuria or proteinuria. The condition is much more predominant in
Guido, Bruce, Gaskill, Neil, Mago, Cynthia   +2 more
core   +1 more source

Predictive role of laboratory markers and clinical features for recurrent Henoch-Schonlein Purpura in childhood: A study from Turkey [PDF]

, 2020
Objectives: Henoch Schonlein Purpura is the most common systemic vasculitis of the childhood. the objective of this study was to evaluate whether there is a clinical significance of laboratory parameters and clinical features on the prediction of the ...
Kurugol, Zafer, Koturoglu, Guldane, Gokce, Sule, Aslan, Asli   +3 more
core   +1 more source

Does clinical exposure to different skin tones during training improve diagnostic ability?

Medical Education, Volume 60, Issue 4, Page 410-417, April 2026.
Abstract Background Previous studies have shown that medical students demonstrate poorer performance when diagnosing pathology in skin of colour (SOC) compared to white skin (WS); it is important to understand the reasons underpinning this. If not addressed, poorer differential diagnostic ability in certain skin tones could entrench existing racial ...
Yusra Shammoon, Anna Coulson, Bethan Trigg, Nariell Morrison, Adam Potts, Moira Pain, Olamide Oguntimehin, Eleanor J. Hothersall‐Davies, Richard Hankins, Celia A. Brown, Amir H. Sam   +10 more
wiley   +1 more source