Results 31 to 40 of about 59,377 (261)

Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs. [PDF]

open access: yesPLoS ONE, 2016
Fifteen different ligands, including heparin (Hep), are cleared from lymph and blood by the Hyaluronan (HA) Receptor for Endocytosis (HARE; derived from Stabilin-2 by proteolysis), which contains four endocytic motifs (M1-M4).
Madhu S Pandey   +3 more
doaj   +1 more source

Effects of UBE2N Knockdown on Radiosensitivity of Human Laryngeal Squamous Cell Carcinoma hep-2 Cells

open access: yesZhongliu Fangzhi Yanjiu, 2019
Objective To investigate the role of UBE2N in the radiosensitivity of laryngocarcinoma hep-2 cells. Methods qPCR and Western blot were used to investigate the silencing efficiency of UBE2N siRNA in hep-2 cells.
GONG Mengxiao   +9 more
doaj   +1 more source

IV Brazilian Guidelines for autoantibodies on HEp-2 cells

open access: yesRevista Brasileira de Reumatologia (English Edition), 2014
The Fourth Brazilian Consensus for Autoantibodies Screening in HEp-2 Cells (ANA) was held in Vitória, Espírito Santo, and aimed to discuss strategies and recommendations about the technique, standardization, interpretation and quality control of the indirect immunofluorescence reaction on HEp-2 cells.Twenty three ANA experts from university centers and
Francescantonio, Paulo Luiz Carvalho   +22 more
openaire   +2 more sources

Isolation and propagation of enteric adenoviruses in HEp-2 cells [PDF]

open access: yesJournal of Clinical Microbiology, 1988
Eighty-two stool samples from children with gastroenteritis in Canada, England, and Thailand which had been shown to contain adenovirus antigen (by a group-specific enzyme-linked immunosorbent assay) or adenovirus particles (by electron microscopy) or both, were tested for primary isolation of enteric adenoviruses in HEp-2 and Graham 293 cells.
Perron-Henry, Dorothy M.   +2 more
openaire   +3 more sources

Aggregative adherent strains of Corynebacterium pseudodiphtheriticum enter and survive within HEp-2 epithelial cells

open access: yesMemorias do Instituto Oswaldo Cruz, 2012
Corynebacterium pseudodiphtheriticum is a well-known human pathogen that mainly causes respiratory disease and is associated with high mortality in compromised hosts. Little is known about the virulence factors and pathogenesis of C. pseudodiphtheriticum.
Monica Cristina de Souza   +10 more
doaj   +1 more source

Cell vacuolation induced by Haemophilus influenzae supernatants in HEp-2 cells [PDF]

open access: yesMemórias do Instituto Oswaldo Cruz, 2013
Haemophilus influenzae belongs to respiratory tract microbiota. We observed vacuoles formation in previous studies with H. influenzae culture supernatants, so in this work we characterised that cytotoxic effect. We observed an abundant production of acidic cytoplasmic vacuoles due to the presence of a "vacuolating factor" in H.
Espinoza-Mellado, Maria del Rosario   +3 more
openaire   +4 more sources

Antisense oligodeoxynucleotides targeting ATM strengthen apoptosis of laryngeal squamous cell carcinoma grown in nude mice

open access: yesJournal of Experimental & Clinical Cancer Research, 2011
Background To conserve laryngeal function and elevate living quality of laryngeal squamous cell carcinoma (LSCC) patients, we designed antisense oligodeoxynucleotides (AS-ODNs) to reduce expression of ATM and to enhance the apoptosis of hep-2 (Human ...
Zhao Yongsheng   +4 more
doaj   +1 more source

The Antiproliferative Activity of Oxypeucedanin via Induction of G2/M Phase Cell Cycle Arrest and p53-Dependent MDM2/p21 Expression in Human Hepatoma Cells

open access: yesMolecules, 2020
Oxypeucedanin (OPD), a furocoumarin compound from Angelica dahurica (Umbelliferae), exhibits potential antiproliferative activities in human cancer cells.
So Hyun Park   +3 more
doaj   +1 more source

Deep Active Learning for Automatic Mitotic Cell Detection on HEp-2 Specimen Medical Images

open access: yesDiagnostics, 2023
Identifying Human Epithelial Type 2 (HEp-2) mitotic cells is a crucial procedure in anti-nuclear antibodies (ANAs) testing, which is the standard protocol for detecting connective tissue diseases (CTD). Due to the low throughput and labor-subjectivity of
Asaad Anaam   +5 more
doaj   +1 more source

Diferenças nas propriedades adesivas de Staphylococcus saprophyticus a células HEp-2 e eritrócitos Differences on the adhesive property of Staphylococcus saprophyticus to HEp-2 cells and erythrocytes

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1992
S. saprophyticus é freqüentemente isolado de infecções do trato urinário de mulheres jovens e sexualmente ativas. Ao contrário de S. aureus, esta espécie não possui fatores de virulência bem definidos. O objetivo deste estudo é analisar a aderência de S.
Lucimar Gonçalves Milagres   +1 more
doaj   +1 more source

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