Brazilian Journal of Medical and Biological Research, 2013 Multidrug resistance (MDR) poses a serious impediment to the success of chemotherapy for laryngeal cancer. To identify microRNAs and mRNAs associated with MDR of human laryngeal cancer Hep-2 cells, we developed a multidrug-resistant human laryngeal ...
Wanzhong Yin +6 more
doaj +4 more sources
Adjunctive role of Q10 with Ligilactobacillus salivarius, and Lactiplantibacillus plantarum probiotic Bacteria on the HEp-2 cells viability and adhesion of Streptococcus mutans [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 ObjectiveVarious studies have indicated the application of Coenzyme Q10 and probiotic bacteria such as Ligilactobacillus salivarius (L. salivarius) and Lactiplantibacillus plantarum (L. plantarum) in combating periodontal disease.
Zohreh Khodaii +4 more
doaj +2 more sources
Lidocaine could promote the cuproptosis through up-regulating the long noncoding RNA DNMBP-AS1 in Hep-2 cells [PDF]
BMC CancerBackground Lidocaine is a traditional local anesthetic, which has been reported to trigger apoptosis through the mitochondrial pathway, independent of death receptor signaling. Cuproptosis is a copper triggered mitochondrial cell death mode.
Wei Liu, Yi Yu, Yi He, Meihong Lv
doaj +2 more sources
Invasion of HEp-2 cells by Shigella spp. isolated from acute pediatric diarrhea [PDF]
GMS Infect Dis, 2017 Aim: infection is an important global health problem in developing countries where hygiene is poor and hence shigellosis is a main cause of diarrhoea-associated mortality and morbidity, particularly in children under the age of five. The bacterial entry
Bakhtiari, R +11 more
core +2 more sources
Aggregative adherent strains of Corynebacterium pseudodiphtheriticum enter and survive within HEp-2 epithelial cells [PDF]
Memorias do Instituto Oswaldo Cruz, 2012 Corynebacterium pseudodiphtheriticum is a well-known human pathogen that mainly causes respiratory disease and is associated with high mortality in compromised hosts. Little is known about the virulence factors and pathogenesis of C. pseudodiphtheriticum.
Monica Cristina de Souza +10 more
doaj +2 more sources
Chamaejasmine Inactivates Akt To Trigger Apoptosis in Human HEp-2 Larynx Carcinoma Cells
Molecules, 2011 In the present study, we investigated the mechanisms of chamaejasmine action on human HEp-2 larynx carcinoma cells, which possess constitutively active Akt.
Dejun Jin +4 more
doaj +2 more sources
Revista do Instituto de Medicina Tropical de São Paulo, 1992 S. saprophyticus é freqüentemente isolado de infecções do trato urinário de mulheres jovens e sexualmente ativas. Ao contrário de S. aureus, esta espécie não possui fatores de virulência bem definidos. O objetivo deste estudo é analisar a aderência de S.
Lucimar Gonçalves Milagres +1 more
doaj +2 more sources
Anti-Nuclear Antibody Screening Using HEp-2 Cells [PDF]
Journal of Visualized Experiments, 2014 The American College of Rheumatology position statement on ANA testing stipulates the use of IIF as the gold standard method for ANA screening(1). Although IIF is an excellent screening test in expert hands, the technical difficulties of processing and reading IIF slides--such as the labor intensive slide processing, manual reading, the need for ...
Carol, Buchner +3 more
openaire +3 more sources
Intracellular localization of Saffold virus Leader (L) protein differs in Vero and HEp-2 cells [PDF]
Emerging Microbes and Infections, 2016 The Saffold virus (SAFV) genome is translated as a single long polyprotein precursor and co-translationally cleaved to yield 12 separate viral proteins. Little is known about the activities of SAFV proteins although their homologs in other picornaviruses
Yishi Xu +5 more
doaj +2 more sources
In vitro and in vivo effect of 5-FC combined gene therapy with TNF-α and CD suicide gene on human laryngeal carcinoma cell line Hep-2. [PDF]
PLoS ONE, 2013 This study was aimed to investigate the effect of combined cancer gene therapy with exogenous tumor necrosis factor-alpha (TNF-α) and cytosine deaminase (CD) suicide gene on laryngeal carcinoma cell line Hep-2 in vitro and in vivo.
Li-Ping Chai +6 more
doaj +1 more source