Adjunctive role of Q10 with Ligilactobacillus salivarius, and Lactiplantibacillus plantarum probiotic Bacteria on the HEp-2 cells viability and adhesion of Streptococcus mutans [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 ObjectiveVarious studies have indicated the application of Coenzyme Q10 and probiotic bacteria such as Ligilactobacillus salivarius (L. salivarius) and Lactiplantibacillus plantarum (L. plantarum) in combating periodontal disease.
Zohreh Khodaii +4 more
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Lidocaine could promote the cuproptosis through up-regulating the long noncoding RNA DNMBP-AS1 in Hep-2 cells [PDF]
BMC CancerBackground Lidocaine is a traditional local anesthetic, which has been reported to trigger apoptosis through the mitochondrial pathway, independent of death receptor signaling. Cuproptosis is a copper triggered mitochondrial cell death mode.
Wei Liu, Yi Yu, Yi He, Meihong Lv
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Apoptosis in HEp-2 cells infected with Ureaplasma diversum [PDF]
Biological Research, 2014 BACKGROUND: Bacterial pathogens have many strategies for infecting and persisting in host cells. Adhesion, invasion and intracellular life are important features in the biology of mollicutes.
Aline Teixeira Amorim +12 more
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Intracellular localization of Saffold virus Leader (L) protein differs in Vero and HEp-2 cells [PDF]
Emerging Microbes and Infections, 2016 The Saffold virus (SAFV) genome is translated as a single long polyprotein precursor and co-translationally cleaved to yield 12 separate viral proteins. Little is known about the activities of SAFV proteins although their homologs in other picornaviruses
Yishi Xu +5 more
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LncRNA CCAT1 facilitates the proliferation, invasion and migration of human laryngeal squamous cell carcinoma cells via the miR-218-5p/BMI1 [PDF]
PeerJ, 2022 Long non-coding RNAs (LncRNAs) are vital in the treatment of laryngeal squamous cell carcinoma (LSCC). This study estimated the mechanism of lncRNA CCAT1 (CCAT1) in LSCC cells. The expression of CCAT1 in the human laryngeal mucosal epithelial cells (HLCs)
Jing Hong +8 more
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Brazilian Journal of Otorhinolaryngology, 2023 Objective: This study aimed to investigate the molecular mechanism of miR-150-5p regulating the malignant biological behavior of Human Epidermoid cancer cell (HEp-2) by targeting peptidyl-prolyl cis/trans isomerase NIMA-Interacting-1 (PIN1).
Hailin Chen +4 more
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundLaryngeal cancer is a type of head and neck tumor with a poor prognosis and survival rate. The new cases of laryngeal cancer increased rapidly with a higher mortality rate around the world.ObjectiveThe current research work was focused to ...
Ben Ye +4 more
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PLoS Pathogens, 2021 Respiratory syncytial virus (RSV) infects the upper and lower respiratory tracts and can cause lower respiratory tract infections in children and elders.
Tiffany King +3 more
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Cancer-associated fibroblasts in a human HEp-2 established laryngeal xenografted tumor are not derived from cancer cells through epithelial-mesenchymal transition, phenotypically activated but karyotypically normal. [PDF]
PLoS ONE, 2015 Cancer-associated fibroblasts (CAFs) play a crucial role in cancer progression and even initiation. However, the origins of CAFs in various cancer types remain controversial, and one of the important hypothesized origins is through epithelial-mesenchymal
Mei Wang +5 more
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Automated Classification of Cell Level of HEp-2 Microscopic Images Using Deep Convolutional Neural Networks-Based Diameter Distance Features [PDF]
Journal of Universal Computer Science, 2023 To identify autoimmune diseases in humans, analysis of HEp-2 staining patterns at cell level is the gold standard for clinical practice research communities.
Mitchell Jensen +3 more
doaj +3 more sources