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Apoptosis in HEp-2 cells infected with Ureaplasma diversum [PDF]

open access: yesBiological Research, 2014
BACKGROUND: Bacterial pathogens have many strategies for infecting and persisting in host cells. Adhesion, invasion and intracellular life are important features in the biology of mollicutes.
Aline Teixeira Amorim   +12 more
doaj   +6 more sources

Diagnosis and treatment of HEp-2 cells contaminated with mycoplasma [PDF]

open access: yesBrazilian Journal of Biology, 2020
Contamination of primary and cell cultures by mycoplasmas is one of the main economic and biological pitfalls in basic research, diagnosis and manufacture of biotechnological products.
B. R. P. Lopes   +7 more
doaj   +6 more sources

LncRNA CCAT1 facilitates the proliferation, invasion and migration of human laryngeal squamous cell carcinoma cells via the miR-218-5p/BMI1 [PDF]

open access: yesPeerJ, 2022
Long non-coding RNAs (LncRNAs) are vital in the treatment of laryngeal squamous cell carcinoma (LSCC). This study estimated the mechanism of lncRNA CCAT1 (CCAT1) in LSCC cells. The expression of CCAT1 in the human laryngeal mucosal epithelial cells (HLCs)
Jing Hong   +8 more
doaj   +2 more sources

MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase

open access: yesBrazilian Journal of Otorhinolaryngology, 2023
Objective: This study aimed to investigate the molecular mechanism of miR-150-5p regulating the malignant biological behavior of Human Epidermoid cancer cell (HEp-2) by targeting peptidyl-prolyl cis/trans isomerase NIMA-Interacting-1 (PIN1).
Hailin Chen   +4 more
doaj   +1 more source

Ononin Shows Anticancer Activity Against Laryngeal Cancer via the Inhibition of ERK/JNK/p38 Signaling Pathway

open access: yesFrontiers in Oncology, 2022
BackgroundLaryngeal cancer is a type of head and neck tumor with a poor prognosis and survival rate. The new cases of laryngeal cancer increased rapidly with a higher mortality rate around the world.ObjectiveThe current research work was focused to ...
Ben Ye   +4 more
doaj   +1 more source

Invasion of Ureaplasma diversum in Hep-2 cells [PDF]

open access: yesBMC Microbiology, 2010
Abstract Background Understanding mollicutes is challenging due to their variety and relationship with host cells. Invasion has explained issues related to their opportunistic role. Few studies have been done on the Ureaplasma diversum mollicute, which is detected in healthy or diseased bovine.
Braga Antonio   +11 more
openaire   +3 more sources

The larger attachment glycoprotein of respiratory syncytial virus produced in primary human bronchial epithelial cultures reduces infectivity for cell lines.

open access: yesPLoS Pathogens, 2021
Respiratory syncytial virus (RSV) infects the upper and lower respiratory tracts and can cause lower respiratory tract infections in children and elders.
Tiffany King   +3 more
doaj   +1 more source

Cancer-associated fibroblasts in a human HEp-2 established laryngeal xenografted tumor are not derived from cancer cells through epithelial-mesenchymal transition, phenotypically activated but karyotypically normal. [PDF]

open access: yesPLoS ONE, 2015
Cancer-associated fibroblasts (CAFs) play a crucial role in cancer progression and even initiation. However, the origins of CAFs in various cancer types remain controversial, and one of the important hypothesized origins is through epithelial-mesenchymal
Mei Wang   +5 more
doaj   +1 more source

Automated Classification of Cell Level of HEp-2 Microscopic Images Using Deep Convolutional Neural Networks-Based Diameter Distance Features [PDF]

open access: yesJournal of Universal Computer Science, 2023
To identify autoimmune diseases in humans, analysis of HEp-2 staining patterns at cell level is the gold standard for clinical practice research communities.
Mitchell Jensen   +3 more
doaj   +3 more sources

Use of HEP-2 Cells for Grouping Enteroviruses [PDF]

open access: yesPublic Health Reports (1896-1970), 1963
WITHIN the enterovirus group of Picornaviruses, 63 serotypes have been recognized (1-3). Since numerous untypable strains are still being isolated in laboratories throughout the world, many new types may be awaiting description and official recognition.
G E, MARCHETTI, H M, GELFAND
openaire   +2 more sources

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