Microbial Models in Screening of Inhibitors of Sterol Biosynthesis
Антибиотики и Химиотерапия, 2020 On the base of previously developed microbial models high effective scheme for screening of inhibitors of sterol biosynthesis (ISB) is proposed. It is based on cultivation of halophilic bacteria Halobacterium salinarum (former Halobacterium halobium ...
A. S. Trenin
doaj
Hepatitis B virus induces cell proliferation via HBx-induced microRNA-21 in hepatocellular carcinoma by targeting programmed cell death protein4 (PDCD4) and phosphatase and tensin homologue (PTEN). [PDF]
PLoS ONE, 2014 Hepatitis B viral infection-induced hepatocellular carcinoma is one of the major problems in the developing countries. One of the HBV proteins, HBx, modulates the host cell machinery via several mechanisms. In this study we hypothesized that HBV enhances
Preeti Damania +7 more
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Cytotoxicity and structure-activity relationships of xanthone derivatives from Mesua beccariana, Mesua ferrea and Mesua congestiflora towards nine human cancer cell lines. [PDF]
, 2013 The cytotoxic structure-activity relationships among a series of xanthone derivatives from Mesua beccariana, Mesua ferrea and Mesua congestiflora were studied. Eleven xanthone derivatives identified as mesuarianone (1), mesuasinone (2), mesuaferrin A (3),
Gwendoline Cheng +5 more
core +3 more sources
Cell Transplantation, 2001 The risk of xenozoonosis infections poses the greatest obstacle against the clinical application of hybrid artificial liver support system (HALSS). Primary human hepatocytes are an ideal source for HALSS, but the shortage of human livers available for ...
Yo-Ichi Yamashita M.D. +10 more
doaj +1 more source
Synthesis of new simplified hemiasterlin derivatives with α,β-unsaturated carbonyl moiety.
, 2014 International audienceIn this Letter, we report a convenient and efficient method for the synthesis of new simplified derivatives of hemiasterlin in which the α,α-dimethylbenzylic moiety A is replaced by α,β-unsaturated aryl groups as Michael acceptor ...
Doan, Duy Tien +10 more
core +2 more sources
Oxygen-dependent expression of the erythropoietin gene in rat hepatocytes in vitro [PDF]
, 1993 Since in juvenile rats the liver is the predominant site of erythropoietin (EPO) gene expression, we have used primary cultures of juvenile rat hepatocytes to establish and in vitro system for investigation of oxygen-dependent EPO formation.
Eckardt, Kai-Uwe +3 more
core +1 more source
Developmental Regulation of Rat Brain/Hep G2 Glucose Transporter Gene Expression [PDF]
Molecular Endocrinology, 1989 The developmental regulation of rat brain-derived/Hep G2 glucose transporter gene expression was studied by means of Northern blot hybridization, using a rat brain glucose transporter cDNA probe, in order to directly quantify steady state glucose transporter mRNA levels.
H, Werner +4 more
openaire +2 more sources
Ceftiofur-loaded PHBV microparticles: A potential formulation for a long-acting antibiotic to treat animal infections [PDF]
, 2012 Indexación: Web of Science; ScieloBackground: The infectious diseases in the livestock breeding industry represent a significant drawback that generates substantial economic loss and have led to the indiscriminate use of antibiotics.
Constandil +5 more
core +1 more source
Nutraceuticals, 2022 Growing location is known to affect the metabolite content and functionality of wild harvested fruits. Terminalia ferdinandiana, commonly known as Kakadu plum (KP), is among the most commercially important native Australian bush foods.
Eshetu M. Bobasa +6 more
doaj +1 more source
Lentiviral vectors with amplified beta cell-specific gene expression. [PDF]
, 2009 An important goal of gene therapy is to be able to deliver genes, so that they express in a pattern that recapitulates the expression of an endogenous cellular gene.
Crooks, GM +7 more
core +2 more sources