Results 51 to 60 of about 35,933 (220)

Copper overload affects copper and iron metabolism in Hep-G2 cells

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2004
Divalent metal transporter #1 (DMT1) is responsible for intestinal nonheme Fe apical uptake. However, DMT1 appears to have an additional function in Cu transport in intestinal cells. Because the liver has an essential role in body Cu homeostasis, we examined the potential involvement of Cu in the regulation of DMT1 expression and activity in Hep-G2 ...
Arredondo, M, Cambiazo, V, Tapia, L, Gonzalez-Aguero, M, Nunez, MT, Uauy, R, Gonzalez, M   +6 more
openaire   +8 more sources

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma, Huan Deng, Zelin Liu, Simei Zhong, Liangliang Wang, Mu He, Ning Jing, Lihua Dai, Yuzhen Basang, Xiao‐Yu Hu, Changyi Zhang, Huimin Zeng, Haoren Shao, Zhe Yang, Shanshan Zhao, Xiaohai Hu, Chuanjie Zhang, Xiaowei Wu, Jing Xu, Shaoqun Zeng, Jing Yuan, Qiang Li, Ziwei Qu, Zhenya Hong, Lingjuan Chen, Hanhua Dong, Jia Guo, Zhiqiang Han, Yu‐Hui Zhang   +28 more
wiley   +1 more source

Phorbol ester inhibits erythropoietin production in human hepatoma cells (Hep G2) [PDF]

American Journal of Physiology-Cell Physiology, 1992
Using the human hepatoma cell line Hep G2, we have studied a possible role of protein kinase C (PKC) activity for regulation of erythropoietin (EPO) production. During a 72-h incubation, EPO production by the cells was stimulated sevenfold by exposure to low oxygen tension (1%) and threefold by exposure to cobaltous chloride (100 microM).
Kurtz, Armin, Eckardt, K. U., Pugh, C., Corvol, P., Fabbro, D., Ratcliffe, P.   +5 more
openaire   +4 more sources

Histopathologic Analysis of the Morpho‐Functional Zones of the Human Acetabular Labrum

Clinical Anatomy, EarlyView.
ABSTRACT The structural and functional adaptation of soft tissues to mechanical load controls their ability to withstand injury and influences their capacity for healing. Similar to the knee meniscus, the acetabular labrum exhibits zonal differences in mechanical load distribution, resulting in distinct regions with unique structural and functional ...
Abdulaziz A. Alomiery, Andrew C. Hall, Thomas H. Gillingwater, Afaf Alsolami, Abduelmenem Alashkham   +4 more
wiley   +1 more source

The Minimal CFL-Nuclear Interface [PDF]

, 2001
At nuclear matter density, electrically neutral strongly interacting matter in weak equilibrium is made of neutrons, protons and electrons. At sufficiently high density, such matter is made of up, down and strange quarks in the color-flavor locked phase,
A. I. Larkin, B. A. Freedman, C. Alcock, C. Manuel, C. Manuel, D. B. Kaplan, D. G. Ravenhall, D. G. Ravenhall, D. G. Ravenhall, D. H. Rischke, D. K. Hong, D. K. Hong, D. T. Son, D. T. Son, E. Farhi, Frank Wilczek, G. Baym, G. W. Carter, H. Heiselberg, H. Heiselberg, I. A. Shovkovy, J. Bowers, J. Negele, K. Rajagopal, K. Zarembo, Krishna Rajagopal, M. Alford, M. Alford, M. Alford, M. Alford, M. Prakash, M. Rho, Mark Alford, N. Evans, N. K. Glendenning, N. K. Glendenning, N. K. Glendenning, N. K. Glendenning, P. Fulde, R. Casalbuoni, R. Casalbuoni, R. Rapp, S. R. Beane, S. Reddy, Sanjay Reddy, T. Norsen, T. Schäfer, T. Schäfer, T. Schäfer, T. Schäfer, T. Schäfer   +50 more
core   +3 more sources

Effects of local event-by-event conservation laws in ultrarelativistic heavy-ion collisions at particlization [PDF]

, 2020
Many simulations of relativistic heavy-ion collisions involve the switching from relativistic hydrodynamics to kinetic particle transport. This switching entails the sampling of particles from the distribution of energy, momentum, and conserved currents ...
Koch, V, Oliinychenko, D, Shi, S
core   +2 more sources

Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects

Future Postharvest and Food, EarlyView.
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq, Sajad Ahmad Mir, Zahida Naseem   +2 more
wiley   +1 more source

p-STAT3 is a PDC-E2 interacting partner in human cholangiocytes and hepatocytes with potential pathobiological implications

Scientific Reports, 2021
The E2 component of the mitochondrial pyruvate dehydrogenase complex (PDC) is the key autoantigen in primary biliary cholangitis (PBC) and STAT3 is an inflammatory modulator that participates in the pathogenesis of many liver diseases.
Ewa Kilanczyk, Jesus M. Banales, Ewelina Jurewicz, Piotr Milkiewicz, Malgorzata Milkiewicz   +4 more
doaj   +1 more source

M-Theory as a Holographic Field Theory [PDF]

, 1997
We suggest that M-theory could be non-perturbatively equivalent to a local quantum field theory. More precisely, we present a ``renormalizable'' gauge theory in eleven dimensions, and show that it exhibits various properties expected of quantum M-theory,
A. Achúcarro, A. H. Chamseddine, A. H. Chamseddine, A. P. Balachandran, A. P. Balachandran, A. Sen, C. M. Hull, D. Kabat, E. Cremmer, E. Fradkin, E. Witten, E. Witten, E. Witten, E. Witten, E. Witten, F. Wilczek, G. ’t Hooft, I. Bars, I. Bars, J. A. de Azcárraga, J. D. Bekenstein, J. H. Schwarz, J. W. van Holten, J. Zanelli, K. Bautier, L. Castellani, L. Castellani, L. Susskind, M. B. Green, M. Bañados, M. Bañados, M. Bañados, M. Bañados, M. R. Douglas, N. Seiberg, P. Fré, P. Hořava, P. Hořava, P. K. Townsend, P. van Nieuwenhuizen, Petr Hořava, R. D’Auria, R. D’Auria, R. Troncoso, S. Carlip, S. Carlip, S. Elizur, S. Weinberg, T. Banks, T. Banks, U. H. Danielsson   +50 more
core   +3 more sources

Electrospun conducting polymers: recent trends and the transition towards a sustainable future

Polymer International, EarlyView.
This review discusses the electrospinning of conducting polymers, detailing procedures, fibrous morphologies, improved properties, applications in electronics, and challenges, while outlining future directions for nanofibre‐based devices in various fields.
Xenofon Karagiorgis, Sofia Sandhu, Peter J. Skabara, Ravinder Dahiya   +3 more
wiley   +1 more source