Results 81 to 90 of about 35,933 (220)

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu   +6 more
wiley   +1 more source

Semistrict Higher Gauge Theory [PDF]

open access: yes, 2015
We develop semistrict higher gauge theory from first principles. In particular, we describe the differential Deligne cohomology underlying semistrict principal 2-bundles with connective structures.
Jurco, Branislav   +2 more
core   +2 more sources

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song   +4 more
wiley   +1 more source

Cryptocaryone Exhibits ROS/MAPK‐Dependent Antiproliferative and Apoptosis‐Inducing Effects on Triple‐Negative Breast Cancer Cells and Proof‐of‐Concept Breast Cancer Mouse Model

open access: yesDrug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Omics’ technologies have enabled clinicians to gain previously unprecedented insights into the molecular complexity and clinical heterogeneity of triple‐negative breast cancer (TNBC). Increasingly it is being realized that TNBC does not respond well to current targeted therapies.
Ya‐Ting Chuang   +6 more
wiley   +1 more source

Eriodictyol-induced anti-cancer and apoptotic effects in human hepatocellular carcinoma cells are associated with cell cycle arrest and modulation of apoptosis-related proteins

open access: yesBangladesh Journal of Pharmacology, 2016
The objective of the present study was to investigate the anti-cancer effects of eriodictyol in human hepatocellular carcinoma cells (Hep-G2) and normal liver hepatocyte cell line (AML12) along with evaluating its mode of action.
Fang Wang   +4 more
doaj   +1 more source

Solanine Attenuates Hepatocarcinoma Migration and Invasion Induced by Acetylcholine

open access: yesIntegrative Cancer Therapies, 2020
Aim: Evidence has provided an explanation of the correlation between the nervous system and the tumor microenvironment. Neurotransmitters may be involved in different aspects of cancer progression. The glycoalkaloid solanine has been reported to suppress
Liang-Tzung Lin   +2 more
doaj   +1 more source

Cytotoxic activity of Ecballium elaterium fruit extract on three cancer cell lines [PDF]

open access: yes
Introduction: Cancer is a common cause of mortality in all of the world specifically in middle age and elderly people. The prevalence of cancer is growing up because the lifetime is going up. In consequence finding on effective treatment for cancer is a
بهلولی, شهاب   +2 more
core  

Twisted Supersymmetric Gauge Theories and Orbifold Lattices

open access: yes, 2006
We examine the relation between twisted versions of the extended supersymmetric gauge theories and supersymmetric orbifold lattices. In particular, for the $\mathcal{N}=4$ SYM in $d=4$, we show that the continuum limit of orbifold lattice reproduces the ...
A.G. Cohen   +21 more
core   +2 more sources

Boundary stress tensors for spherically symmetric conformal Rindler observers [PDF]

open access: yes, 2010
The boundary energy - momentum tensors for a static observer in the conformally flat Rindler geometry are considered. We found the surface energy is positive far form the Planck world but the transversal pressures are negative. The kinematical parameters
Culetu, Hristu
core   +1 more source

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