Results 111 to 120 of about 20,741 (247)

The occurrence of liver steatosis in patients with chronic hepatitis C - the experience of the Clinical Center of Vojvodina [PDF]

open access: yesVojnosanitetski Pregled, 2018
Background/Aim. Hepatic steatosis in patients with chronic hepatitis C occurs in about half of the cases. Its occurrence is influenced by factors of the host and viral factors and its importance lies in the fact that it reduces the success of antiviral ...
Preveden Tomislav   +4 more
doaj   +1 more source

Reconstruction of the historic time course of blood‐borne virus contamination of clotting factor concentrates, 1974–1992

open access: yesJournal of Medical Virology, Volume 96, Issue 7, July 2024.
Abstract Factor VIII and IX clotting factor concentrates manufactured from pooled plasma have been identified as potent sources of virus infection in persons with hemophilia (PWHs) in the 1970s and 1980s. To investigate the range and diversity of viruses over this period, we analysed 24 clotting factor concentrates for several blood‐borne viruses ...
C. Patrick McClure   +13 more
wiley   +1 more source

First identification and phylogenetic analysis of equine hepacivirus in Korea

open access: yesInfection, Genetics and Evolution, 2017
Non-primate hepacivirus (NPHV) corresponds a group of isolates recently characterized in horses and dogs that present similar genomic organization and are closely related to hepatitis C virus. Since canine hapacivirus, NPHV identified in dogs, was first discovered in dogs in the United States, equine hepacivirus (EqHV, NPHV identified in horses) has ...
Hyuk Moo Kwon   +3 more
openaire   +3 more sources

Development of Optimized Inhibitor RNAs Allowing Multisite-Targeting of the HCV Genome [PDF]

open access: yes, 2017
: Engineered multivalent drugs are promising candidates for fighting infection by highly variable viruses, such as HCV. The combination into a single molecule of more than one inhibitory domain, each with its own target specificity and even a different ...
Berzal-Herranz, Alfredo   +3 more
core   +1 more source

Improving the safety of CAR‐T‐cell therapy: The risk and prevention of viral infection for patients with relapsed or refractory B‐cell lymphoma undergoing CAR‐T‐cell therapy

open access: yesAmerican Journal of Hematology, Volume 99, Issue 4, Page 662-678, April 2024.
Risk factors and prevention recommendations for viral infections in CAR T‐cell therapy. Abstract Chimeric antigen receptor (CAR) T‐cell therapy, an innovative immunotherapeutic against relapsed/refractory B‐cell lymphoma, faces challenges due to frequent viral infections.
Hu Qian   +7 more
wiley   +1 more source

Il Trattamento Della Recidiva di Epatite C dopo Trapianto di Fegato con Sofosbuvir e Ribavirina [PDF]

open access: yes, 2016
Introduzione: Sono ancora poco conosciute le variabili cliniche in grado di predire l’insuccesso della terapia antivirale di combinazione con sofosbuvir (SOF) e ribavirina (RIBA) nei pazienti sottoposti a trapianto di fegato (LT) e affetti da recidiva di
RETI, SILVIA LAURA
core  

Electron microscopy: The key to resolve RNA viruses replication organelles

open access: yesMolecular Microbiology, Volume 121, Issue 4, Page 679-687, April 2024.
Positive‐strand RNA viruses replicate their genome within specialized virus‐induced intracellular compartments called “replication organelles”. Technological advances in electron microscopy allowed detailed characterization of such structures unveiling their three‐dimensional architecture and molecular composition.
Debora Stelitano, Mirko Cortese
wiley   +1 more source

Mutations within the hepatitis C virus genotype 1b E2-PePHD domain do not correlate with treatment outcome. [PDF]

open access: yes, 2005
The hepatitis C virus (HCV) envelope protein 2 (E2) interacts in vitro with the interferon alpha (IFN-alpha)-inducible double-stranded RNA-activated protein kinase, suggesting a possible mechanism by which HCV may evade the antiviral effects of IFN-alpha.
A. Goudeau   +5 more
core   +3 more sources

Trends in the burden of most common obesity‐related cancers in 16 Southern Africa development community countries, 1990–2019. Findings from the global burden of disease study

open access: yesObesity Science &Practice, Volume 10, Issue 1, February 2024.
Obesity‐related cancers in the 16 SADC countries is quite prominent but the time trends in mortality are unknown. We analyzed data obtained from the 2019 Global Burden of Diseases Study. For males in 2019, mortality rates for leukaemia, oesophageal, colon/rectum cancer were the most prominent, whereas for females, breast cancer, leukaemia, oesophageal ...
Philimon Gona   +6 more
wiley   +1 more source

Proposed update to the taxonomy of the genera Hepacivirus and Pegivirus within the Flaviviridae family [PDF]

open access: yesJournal of General Virology, 2016
Proposals are described for the assignment of recently reported viruses, infecting rodents, bats and other mammalian species, to new species within the Hepacivirus and Pegivirus genera (family Flaviviridae). Assignments into 14 Hepacivirus species (Hepacivirus A– N) and 11 Pegivirus species (Pegivirus A– K) are based
Alexander G. Pletnev   +12 more
openaire   +5 more sources

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