Results 111 to 120 of about 20,741 (247)
The occurrence of liver steatosis in patients with chronic hepatitis C - the experience of the Clinical Center of Vojvodina [PDF]
Background/Aim. Hepatic steatosis in patients with chronic hepatitis C occurs in about half of the cases. Its occurrence is influenced by factors of the host and viral factors and its importance lies in the fact that it reduces the success of antiviral ...
Preveden Tomislav+4 more
doaj +1 more source
Abstract Factor VIII and IX clotting factor concentrates manufactured from pooled plasma have been identified as potent sources of virus infection in persons with hemophilia (PWHs) in the 1970s and 1980s. To investigate the range and diversity of viruses over this period, we analysed 24 clotting factor concentrates for several blood‐borne viruses ...
C. Patrick McClure+13 more
wiley +1 more source
First identification and phylogenetic analysis of equine hepacivirus in Korea
Non-primate hepacivirus (NPHV) corresponds a group of isolates recently characterized in horses and dogs that present similar genomic organization and are closely related to hepatitis C virus. Since canine hapacivirus, NPHV identified in dogs, was first discovered in dogs in the United States, equine hepacivirus (EqHV, NPHV identified in horses) has ...
Hyuk Moo Kwon+3 more
openaire +3 more sources
Development of Optimized Inhibitor RNAs Allowing Multisite-Targeting of the HCV Genome [PDF]
: Engineered multivalent drugs are promising candidates for fighting infection by highly variable viruses, such as HCV. The combination into a single molecule of more than one inhibitory domain, each with its own target specificity and even a different ...
Berzal-Herranz, Alfredo+3 more
core +1 more source
Risk factors and prevention recommendations for viral infections in CAR T‐cell therapy. Abstract Chimeric antigen receptor (CAR) T‐cell therapy, an innovative immunotherapeutic against relapsed/refractory B‐cell lymphoma, faces challenges due to frequent viral infections.
Hu Qian+7 more
wiley +1 more source
Il Trattamento Della Recidiva di Epatite C dopo Trapianto di Fegato con Sofosbuvir e Ribavirina [PDF]
Introduzione: Sono ancora poco conosciute le variabili cliniche in grado di predire l’insuccesso della terapia antivirale di combinazione con sofosbuvir (SOF) e ribavirina (RIBA) nei pazienti sottoposti a trapianto di fegato (LT) e affetti da recidiva di
RETI, SILVIA LAURA
core
Electron microscopy: The key to resolve RNA viruses replication organelles
Positive‐strand RNA viruses replicate their genome within specialized virus‐induced intracellular compartments called “replication organelles”. Technological advances in electron microscopy allowed detailed characterization of such structures unveiling their three‐dimensional architecture and molecular composition.
Debora Stelitano, Mirko Cortese
wiley +1 more source
Mutations within the hepatitis C virus genotype 1b E2-PePHD domain do not correlate with treatment outcome. [PDF]
The hepatitis C virus (HCV) envelope protein 2 (E2) interacts in vitro with the interferon alpha (IFN-alpha)-inducible double-stranded RNA-activated protein kinase, suggesting a possible mechanism by which HCV may evade the antiviral effects of IFN-alpha.
A. Goudeau+5 more
core +3 more sources
Obesity‐related cancers in the 16 SADC countries is quite prominent but the time trends in mortality are unknown. We analyzed data obtained from the 2019 Global Burden of Diseases Study. For males in 2019, mortality rates for leukaemia, oesophageal, colon/rectum cancer were the most prominent, whereas for females, breast cancer, leukaemia, oesophageal ...
Philimon Gona+6 more
wiley +1 more source
Proposed update to the taxonomy of the genera Hepacivirus and Pegivirus within the Flaviviridae family [PDF]
Proposals are described for the assignment of recently reported viruses, infecting rodents, bats and other mammalian species, to new species within the Hepacivirus and Pegivirus genera (family Flaviviridae). Assignments into 14 Hepacivirus species (Hepacivirus A– N) and 11 Pegivirus species (Pegivirus A– K) are based
Alexander G. Pletnev+12 more
openaire +5 more sources