Results 121 to 130 of about 20,741 (247)

Integration of Planova filters in manufacturing processes of biologicals improve the virus safety effectively: A review of publicly available data

Biotechnology Progress, Volume 40, Issue 1, January/February 2024.
Abstract The capacity to remove viruses by Planova filters produced by Asahi Kasei, primarily by small virus‐retentive filters, were compiled from data in peer‐reviewed publications and, partly, publicly available data from presentations at conferences (Planova workshops).
Albrecht Gröner
wiley   +1 more source

Natural reservoirs for homologs of hepatitis C virus

Emerging Microbes and Infections, 2014
Hepatitis C virus is considered a major public health problem, infecting 2%–3% of the human population. Hepatitis C virus infection causes acute and chronic liver disease, including chronic hepatitis, cirrhosis and hepatocellular carcinoma.
Stephanie Pfaender, Richard JP Brown, Thomas Pietschmann, Eike Steinmann   +3 more
doaj   +1 more source

Quasispecies evolution in NS5A region of hepatitis C virus genotype 1b during interferon or combined interferon-ribavirin therapy [PDF]

, 2007
AIM: To evaluate the implication of substitutions in the hepatitis C virus (HCV) non-structural 5A (NS5A) protein in the resistance of HCV during mono-interferon (IFN) or combined IFN-ribavirin (IFN-R) therapy. Although NS5A has been reported to interact
C. Gaudy-Graffin, C. Payan, F. Lunel-Fabiani, H. Le Guillou-Guillemette, P. Veillon   +4 more
core   +2 more sources

Characterisation of putative novel tick viruses and zoonotic risk prediction

Ecology and Evolution, Volume 14, Issue 1, January 2024.
Tick‐borne viruses remain a substantial zoonotic risk worldwide, so knowledge of the diversity of tick viruses has potential health consequences. Through data mining and bioinformatic analyses of more than 37,800 public meta‐genomic and ‐transcriptomic data sets, we found five putative novel Alphatetra‐like viruses, four putative novel Orthomyxo‐like ...
Yuting Lin, David J. Pascall
wiley   +1 more source

A highly divergent hepacivirus-like flavivirus in domestic ducks

Journal of General Virology, 2019
Using random amplification and reverse transcription-PCR, a novel RNA virus was detected in sera of domestic ducks. The full genome of the virus was determined for three strains, identifying the first hepacivirus-like flavivirus in birds. The virus, that we tentatively named duck hepacivirus-like virus (DuHV), possesses several unique molecular ...
Lili Chu, Meiling Jin, Chonglun Feng, Xiaoyan Wang, Dabing Zhang   +4 more
openaire   +3 more sources

Metformin and statins reduce hepatocellular carcinoma risk in chronic hepatitis C patients with failed antiviral therapy [PDF]

Clinical and Molecular Hepatology
Background/Aims Chronic hepatitis C (CHC) patients who failed antiviral therapy are at increased risk for hepatocellular carcinoma (HCC). This study assessed the potential role of metformin and statins, medications for diabetes mellitus (DM) and ...
Pei-Chien Tsai, Chung-Feng Huang, Ming-Lun Yeh, Meng-Hsuan Hsieh, Hsing-Tao Kuo, Chao-Hung Hung, Kuo-Chih Tseng, Hsueh-Chou Lai, Cheng-Yuan Peng, Jing-Houng Wang, Jyh-Jou Chen, Pei-Lun Lee, Rong-Nan Chien, Chi-Chieh Yang, Gin-Ho Lo, Jia-Horng Kao, Chun-Jen Liu, Chen-Hua Liu, Sheng-Lei Yan, Chun-Yen Lin, Wei-Wen Su, Cheng-Hsin Chu, Chih-Jen Chen, Shui-Yi Tung, Chi‐Ming Tai, Chih-Wen Lin, Ching-Chu Lo, Pin-Nan Cheng, Yen-Cheng Chiu, Chia-Chi Wang, Jin-Shiung Cheng, Wei-Lun Tsai, Han-Chieh Lin, Yi-Hsiang Huang, Chi-Yi Chen, Jee-Fu Huang, Chia-Yen Dai, Wan-Long Chung, Ming-Jong Bair, Ming-Lung Yu, T-COACH Study Group   +40 more
doaj   +1 more source

The KNIME Based Classification Models for Yellow Fever Virus Inhibition [PDF]

, 2015
The Naïve Bayes method as implemented in KNIME platform for classification of YFV inhibition. The best classification model is able to correctly discriminate >90% of inhibitors and non-inhibitors.
Moorthy, NHS, Poongavanam, Vasanthanathan   +1 more
core   +1 more source

Clinical Relevance and Drug Modulation of PPAR Signaling Pathway in Triple‐Negative Breast Cancer: A Comprehensive Analysis

PPAR Research, Volume 2024, Issue 1, 2024.
Triple‐negative breast cancer (TNBC) is highly heterogeneous and poses a significant medical challenge due to limited treatment options and poor outcomes. Peroxisome proliferator‐activated receptors (PPARs) play a crucial role in regulating metabolism and cell fate. While the association between PPAR signal and human cancers has been a topic of concern,
Yanxia Zhang, Yunduo Liu, Mei Zhang, Guanjie Li, Siling Zhu, Keping Xie, Bin Xiao, Linhai Li, Sheryar Afzal   +8 more
wiley   +1 more source

Equine hepacivirus persistent infection in a horse with chronic wasting

Transboundary and Emerging Diseases, 2017
Equine hepacivirus is the closest homologue of hepatitis C virus. Limited data on the clinical features of this infection are available. We report the identification of a horse with high-titre viremia by equine hepacivirus. Over a 15-month follow-up, the clinical signs and the viremic status persisted, suggesting a chronic evolution.
G. Elia, G. Lanave, E. Lorusso, A. Parisi, A. Trotta, R. Buono, V. Martella, N. Decaro, C. Buonavoglia   +8 more
openaire   +4 more sources

The eukaryotic linear motif resource ELM: 10 years and counting [PDF]

, 2013
The eukaryotic linear motif (ELM http://elm.eu.org) resource is a hub for collecting, classifying and curating information about short linear motifs (SLiMs).
Altenberg, Brigitte, Born, Diana, Budd, Aidan, Chemes, Lucia Beatriz, Davey, Norman E., Diella, Francesca, Dinkel, Holder, Gibson, Toby J, Glavina, Juliana, Grebnev, Gleb, Kruger, Daniel, Kuban, Marta, Michael, Sushama, Seiler, Markus, Speck, Tobias, Strumillo, Marta, Sánchez Miguel, Ignacio Enrique, Uyar, Bora, Van Roey, Kim, Weatheritt, Robert J.   +19 more
core   +6 more sources