Results 121 to 130 of about 43,714 (247)
Identification of equine hepacivirus infections in France: Facts and Physiopathological insights
Journal of Equine Veterinary Science, 2016 Hepatitis C virus (HCV) is one of the main causes of end stage liver diseases (cirrhosis and hepatocellular carcinoma) in humans. In vivo studies have been hampered by a lack of access to relevant animal models. Until recently, the genus Hepacivirus was comprised of seven HCV genotypes, plus GBV-B that infects New World monkeys.
Stéphane Pronost +8 more
openalex +3 more sources
Journal of Medical Virology, Volume 96, Issue 7, July 2024.Abstract Factor VIII and IX clotting factor concentrates manufactured from pooled plasma have been identified as potent sources of virus infection in persons with hemophilia (PWHs) in the 1970s and 1980s. To investigate the range and diversity of viruses over this period, we analysed 24 clotting factor concentrates for several blood‐borne viruses ...
C. Patrick McClure +13 more
wiley +1 more source
Proposed update to the taxonomy of the genera Hepacivirus and Pegivirus within the Flaviviridae family [PDF]
Journal of General Virology, 2016 Proposals are described for the assignment of recently reported viruses, infecting rodents, bats and other mammalian species, to new species within the Hepacivirus and Pegivirus genera (family Flaviviridae). Assignments into 14 Hepacivirus species (Hepacivirus A– N) and 11 Pegivirus species (Pegivirus A– K) are based
Alexander G. Pletnev +12 more
openaire +5 more sources
American Journal of Hematology, Volume 99, Issue 4, Page 662-678, April 2024.Risk factors and prevention recommendations for viral infections in CAR T‐cell therapy. Abstract Chimeric antigen receptor (CAR) T‐cell therapy, an innovative immunotherapeutic against relapsed/refractory B‐cell lymphoma, faces challenges due to frequent viral infections.
Hu Qian +7 more
wiley +1 more source
Electron microscopy: The key to resolve RNA viruses replication organelles
Molecular Microbiology, Volume 121, Issue 4, Page 679-687, April 2024.Positive‐strand RNA viruses replicate their genome within specialized virus‐induced intracellular compartments called “replication organelles”. Technological advances in electron microscopy allowed detailed characterization of such structures unveiling their three‐dimensional architecture and molecular composition.
Debora Stelitano, Mirko Cortese
wiley +1 more source
A highly divergent hepacivirus-like flavivirus in domestic ducks
Journal of General Virology, 2019 Using random amplification and reverse transcription-PCR, a novel RNA virus was detected in sera of domestic ducks. The full genome of the virus was determined for three strains, identifying the first hepacivirus-like flavivirus in birds. The virus, that we tentatively named duck hepacivirus-like virus (DuHV), possesses several unique molecular ...
Lili Chu +4 more
openaire +3 more sources
Metformin and statins reduce hepatocellular carcinoma risk in chronic hepatitis C patients with failed antiviral therapy [PDF]
Clinical and Molecular HepatologyBackground/Aims Chronic hepatitis C (CHC) patients who failed antiviral therapy are at increased risk for hepatocellular carcinoma (HCC). This study assessed the potential role of metformin and statins, medications for diabetes mellitus (DM) and ...
Pei-Chien Tsai +40 more
doaj +1 more source
Development of diagnostic methods and study of the immunoreactivity of a mixture of recombinant core and E2 proteins fused to GST with control serum positive for hepatitis C [PDF]
, 2013 The hepatitis C virus (HCV) is an enveloped virus that is about 50–70nm in diameter, has positive-strand RNA, and belongs to the genus Hepacivirus and the family Flaviridae.
Kenfe, Flávia Regina +5 more
core +1 more source
Hepatitis viruses: prevalence of equine parvovirus‐hepatitis virus and equine hepacivirus in France and Australia [PDF]
, 2021 Christine Fortier +11 more
openalex +1 more source
Equine hepacivirus persistent infection in a horse with chronic wasting
Transboundary and Emerging Diseases, 2017 Equine hepacivirus is the closest homologue of hepatitis C virus. Limited data on the clinical features of this infection are available. We report the identification of a horse with high-titre viremia by equine hepacivirus. Over a 15-month follow-up, the clinical signs and the viremic status persisted, suggesting a chronic evolution.
G. Elia +8 more
openaire +4 more sources