Results 131 to 140 of about 44,632 (248)
Gut and Liver, 2017 Background/AimsThe present study aimed to evaluate the safety and efficacy of simeprevir-based triple therapy with reduced doses of pegylated interferon (PEG-IFN) and ribavirin for interferon (IFN) ineligible patients, such as elderly and/or cirrhotic ...
Hideyuki Tamai +11 more
doaj +1 more source
Correlative Scanning-Transmission Electron Microscopy Reveals that a Chimeric Flavivirus Is Released as Individual Particles in Secretory Vesicles. [PDF]
, 2014 International audienceThe intracellular morphogenesis of flaviviruses has been well described, but flavivirus release from the host cell remains poorly documented.
Caroline, Sellin +6 more
core +4 more sources
Gut and Liver, 2016 Background/AimsThis study aimed to predict sustained viral response (SVR) to low-dose pegylated interferon (PEG-IFN) plus ribavirin of elderly and/or cirrhotic patients with genotype 2 hepatitis C virus (HCV) using viral response within 2 weeks.Methods :
Hideyuki Tamai +12 more
doaj +1 more source
Uji Saring Antigen dan Antibodi Hepatitis C Virus pada Darah Donor [PDF]
, 2015 According to the data from Central Blood Transfusion Unit, the prevalence of hepatitis C virus (HCV) in blood donors in Indonesia and especially Jakarta in 2012 were 0.39% and 0.36% respectively.
Ibrahim, F. (Fera) +3 more
core
Modeling HCV disease in animals: virology, immunology and pathogenesis of HCV and GBV-B infections [PDF]
, 2014 Hepatitis C virus (HCV) infection has become a global public health burden costing billions of dollars in health care annually. Even with rapidly advancing scientific technologies this disease still poses a significant threat due to a lack of vaccines ...
Manickam, Cordelia, Reeves, R. Keith
core +2 more sources
Gut and Liver, 2017 Background/AimsAccording to the results of several studies, the outcome of hepatitis C virus (HCV) reactivation is not as severe as the outcome of hepatitis B virus reactivation.
Hae Lim Lee +13 more
doaj +1 more source
Inhibition of RNA helicases of ssRNA+ virus belonging to Flaviviridae, Coronaviridae and Picornaviridae families [PDF]
, 2011 Many viral pathogens encode the motor proteins named RNA helicases which display various functions in genome replication. General strategies to design specific and selective drugs targeting helicase for the treatment of viral infections could act via one
Briguglio, Irene +3 more
core
Evolving drug therapies for chronic hepatitis C: Immunomodulation and beyond [PDF]
, 2011 Chronic hepatitis C infection is a major health problem and a leading cause of chronic liver disease. The hepatitis C virus was discovered in 1989 (1, 2).
Bergmann, J.F. (Jilling)
core
Space constrained homology modelling: The paradigm of the RNA-dependent RNA polymerase of dengue (Type II) virus [PDF]
, 2013 Protein structure is more conserved than sequence in nature. In this direction we developed a novel methodology that significantly improves conventional homology modelling when sequence identity is low, by taking into consideration 3D structural features
Kontopoulos, DG +2 more
core +2 more sources