Results 131 to 140 of about 20,741 (247)

Comprehensive evolutionary and phylogenetic analysis of Hepacivirus N (HNV)

Journal of General Virology, 2018
Hepaciviruses (HVs) have been detected in several domestic and wild animals and present high genetic diversity. The actual classification divides the genus Hepacivirus into 14 species (A-N), according to their phylogenetic relationships, including the bovine hepacivirus [Hepacivirus N (HNV)].
M. S. da Silva, V. C. S. Coimbra, A. C. S. Mósena, Cláudio Wageck Canal, Simone Silveira, L. F. Baumbach, Matheus Nunes Weber, Ricardo Maia, Dennis Maletich Junqueira, Samuel Paulo Cibulski, G. M. de Moraes   +10 more
openaire   +3 more sources

Correlative Scanning-Transmission Electron Microscopy Reveals that a Chimeric Flavivirus Is Released as Individual Particles in Secretory Vesicles. [PDF]

, 2014
International audienceThe intracellular morphogenesis of flaviviruses has been well described, but flavivirus release from the host cell remains poorly documented.
Caroline, Sellin, Claude, Lebos, Gaillard, Julien, Jean-Marc, Guillaume, Roingeard, Philippe, Sonia, Georgeault, Uzbekov, Rustem   +6 more
core   +3 more sources

Caracterização dos gêneros Pestivirus e Hepacivirus com a finalidade de identificação para possível desenvolvimento de kits diagnósticos específicos [PDF]

, 2022
Priscilla Schoeps Felicio
openalex   +1 more source

Development of diagnostic methods and study of the immunoreactivity of a mixture of recombinant core and E2 proteins fused to GST with control serum positive for hepatitis C [PDF]

, 2013
The hepatitis C virus (HCV) is an enveloped virus that is about 50–70nm in diameter, has positive-strand RNA, and belongs to the genus Hepacivirus and the family Flaviridae.
Kenfe, Flávia Regina, Urbaczek, Ana Carolina, Silva, Juliana Cristina, Néo, Thalita Athie, da Silva, Flávio Henrique, da Costa, Paulo Inácio   +5 more
core   +1 more source

Design and nonviral delivery of live attenuated vaccine to prevent chronic hepatitis C virus-like infection

Nature Communications
An effective vaccine for the hepatitis C virus (HCV) remains an unmet medical need. There is no animal model for assessing HCV vaccines; however, rodent hepacivirus (RHV) infection in laboratory rats recapitulates the lifelong chronic hepatotropic ...
Sheetal Trivedi, Piyush Dravid, Tim C. Passchier, Satyapramod Murthy, Kripa Shanker Kasudhan, Narendran Reguraman, Justin Kellar, Rahul Chandra, Cole Cassady, Peter D. Burbelo, Arash Grakoui, Himanshu Sharma, Peter Simmonds, Amit Kapoor   +13 more
doaj   +1 more source

Simeprevir-Based Triple Therapy with Reduced Doses of Pegylated Interferon α-2a Plus Ribavirin for Interferon Ineligible Patients with Genotype 1b Hepatitis C Virus

Gut and Liver, 2017
Background/AimsThe present study aimed to evaluate the safety and efficacy of simeprevir-based triple therapy with reduced doses of pegylated interferon (PEG-IFN) and ribavirin for interferon (IFN) ineligible patients, such as elderly and/or cirrhotic ...
Hideyuki Tamai, Yoshiyuki Ida, Akira Kawashima, Naoki Shingaki, Ryo Shimizu, Kosaku Moribata, Tetsushi Nasu, Takao Maekita, Mikitaka Iguchi, Jun Kato, Taisei Nakao, Masayuki Kitano   +11 more
doaj   +1 more source

Low-Dose Pegylated Interferon α-2b Plus Ribavirin for Elderly and/or Cirrhotic Patients with Genotype 2 Hepatitis C Virus

Gut and Liver, 2016
Background/AimsThis study aimed to predict sustained viral response (SVR) to low-dose pegylated interferon (PEG-IFN) plus ribavirin of elderly and/or cirrhotic patients with genotype 2 hepatitis C virus (HCV) using viral response within 2 weeks.Methods :
Hideyuki Tamai, Naoki Shingaki, Yoshiyuki Mori, Kosaku Moribata, Akira Kawashima, Yoshimasa Maeda, Toru Niwa, Hisanobu Deguchi, Izumi Inoue, Takao Maekita, Mikitaka Iguchi, Jun Kato, Masao Ichinose   +12 more
doaj   +1 more source

Uji Saring Antigen dan Antibodi Hepatitis C Virus pada Darah Donor [PDF]

, 2015
According to the data from Central Blood Transfusion Unit, the prevalence of hepatitis C virus (HCV) in blood donors in Indonesia and especially Jakarta in 2012 were 0.39% and 0.36% respectively.
Ibrahim, F. (Fera), Rini, P. (Pierlita), Setiawaty, V. (Vivi), Soedarmono, Y. (Yuyun)   +3 more
core  

Metabolic Dysregulation in Hepacivirus Infection of Common Marmosets (Callithrix jacchus)

PLOS ONE, 2017
Chronic hepatitis C has been associated with metabolic syndrome that includes insulin resistance, hepatic steatosis and obesity. These metabolic aberrations are risk factors for disease severity and treatment outcome in infected patients. Experimental infection of marmosets with GBV-B serves as a tangible, small animal model for human HCV infection ...
Manickam, Cordelia, Martinot, Amanda, Wachtman, Lynn, Giavedoni, Luis D., Reeves, R. Keith   +4 more
openaire   +6 more sources

Reactivation of Hepatitis C Virus and Its Clinical Outcomes in Patients Treated with Systemic Chemotherapy or Immunosuppressive Therapy

Gut and Liver, 2017
Background/AimsAccording to the results of several studies, the outcome of hepatitis C virus (HCV) reactivation is not as severe as the outcome of hepatitis B virus reactivation.
Hae Lim Lee, Si Hyun Bae, Bohyun Jang, Seawon Hwang, Hyun Yang, Hee Chul Nam, Pil Soo Sung, Sung Won Lee, Jeong Won Jang, Jong Young Choi, Nam Ik Han, Byung Joo Song, Jong Wook Lee, Seung Kew Yoon   +13 more
doaj   +1 more source