Space constrained homology modelling: The paradigm of the RNA-dependent RNA polymerase of dengue (Type II) virus [PDF]
, 2013 Protein structure is more conserved than sequence in nature. In this direction we developed a novel methodology that significantly improves conventional homology modelling when sequence identity is low, by taking into consideration 3D structural features
Kontopoulos, DG +2 more
core +2 more sources
Evolving drug therapies for chronic hepatitis C: Immunomodulation and beyond [PDF]
, 2011 Chronic hepatitis C infection is a major health problem and a leading cause of chronic liver disease. The hepatitis C virus was discovered in 1989 (1, 2).
Bergmann, J.F. (Jilling)
core
Inhibition of RNA helicases of ssRNA+ virus belonging to Flaviviridae, Coronaviridae and Picornaviridae families [PDF]
, 2011 Many viral pathogens encode the motor proteins named RNA helicases which display various functions in genome replication. General strategies to design specific and selective drugs targeting helicase for the treatment of viral infections could act via one
Briguglio, Irene +3 more
core
Busca por Hepacivirus semelhante ao vírus da hepatite C, em primatas não humanos [PDF]
, 2013 Gustavo Moraes Holanda +2 more
openalex +1 more source
Prospects for prophylactic hepatitis C vaccines based on virus-like particles. [PDF]
, 2013 International audienceGiven the global prevalence and long-term complications of chronic hepatitis C virus (HCV) infection, HCV constitutes one of the greatest challenges to human health of this decade.
Beaumont, Elodie, Roingeard, Philippe
core +3 more sources
Journal of Medical Microbiology and Infectious Diseases, 2020 Introduction: Hepatitis C virus (HCV) infection and type 2 Diabetes Mellitus (T2DM) are among the severe threats to health care systems worldwide. Here, we investigated the association of HCV genotypes and cirrhosis with T2DM among HCV-positive patients.
Parviz Saleh +4 more
doaj
Efectos adversos más frecuentes de los nuevos antivirales anti-VHC [PDF]
, 2016 Introducción y antecedentes: La infección por el virus de la hepatitis C es un problema que afecta a nivel mundial, por ello en España se han tomado medidas para combatir esta enfermedad a través de un plan estratégico emitido por el Ministerio de ...
Barreda León, Mª Pilar
core
The SWISS-MODEL Repository and associated resources [PDF]
, 2017 SWISS-MODEL Repository (http://swissmodel.expasy.org/repository/) is a database of 3D protein structure models generated by the SWISS-MODEL homology-modelling pipeline.
Arnold, Konstantin +4 more
core
A Novel Genetic Group of Bovine Hepacivirus in Archival Serum Samples from Brazilian Cattle [PDF]
, 2017 Cláudio Wageck Canal +6 more
openalex +1 more source
Extrahepatic manifestations of hepatitis C virus infection [PDF]
Vojnosanitetski Pregled, 2003 Nožić Darko
doaj +1 more source