Results 221 to 230 of about 20,741 (247)

Identification of a mimotope of a complex gp41 human immunodeficiency virus epitope related to a non-structural protein of Hepacivirus previously implicated in Kawasaki disease

bioRxiv
Current HIV vaccine strategies are hampered by difficulty with recapitulating heavily mutated broadly neutralizing antibodies. We have previously isolated a highly mutated antibody termed “group C 76-Q13-6F5” (6F5) that uses immunoglobulin heavy chain ...
H. Sojar, S. Baron, M. Hicar
semanticscholar   +4 more sources

Analysis of genetic polymorphisms and drug resistance mutations in the NS5 region of HCV genome (Flasuviricetes: Amarillovirales: Flaviviridae: Hepacivirus C) in samples obtained in 2022–2023 from HIV-infected treatment-naive residents of Altai Krai

Problems of virology
Introduction. Altai Krai is a region with an unfavorable situation of HIV-1 and HCV infection, as well as HIV-1 and HCV coinfection. Due to this, it is necessary to study the HCV genetic variants and their drug resistance (DR) to direct-acting antivirals
I. Lapovok, Arina Syrkina, A. Kirichenko, A. Shlykova, N. V. Lukyanenko, T. V. Safyanova, Arina E. Safronova, V. V. Shevchenko, D. Kireev   +8 more
semanticscholar   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Genetic heterogeneity of bovine hepacivirus in Italy

Transboundary and Emerging Diseases, 2020
Viruses similar to human hepatitis C virus (HCV) in the Hepacivirus genus have been identified in several animal hosts, including cattle. Since its first discovery in Germany, bovine hepacivirus (BovHepV) has been described in several countries globally. However, limited data are available on BovHepV epidemiology and genetic variability.
Gabriella Elia, Francesca Caringella, Gianvito Lanave, Vito Martella, Michele Losurdo, Manuela Tittarelli, Barbara Colitti, Nicola Decaro, Canio Buonavoglia   +8 more
openaire   +5 more sources

Presence of bovine hepacivirus in Turkish cattle

Veterinary Microbiology, 2018
Hepatitis C virus (HCV), a worldwide distributed human pathogen, causes one of the most important viral infections in human being. HCV is the type species of the genus Hepacivirus (Flaviviridae) in which recently discovered animal viruses i.e. from horses, bats, rodents and cattle are allocated. After preliminary reports in 2015 from German and African
Alpay, GİZEM, YEŞİLBAĞ, KADİR, KADİROĞLU, BERFİN, Toker, EDA BALDAN, Becher, Paul, Baechlein, Christine   +5 more
openaire   +3 more sources

Detection of a novel hepacivirus in wild cavies (Cavia aperea aperea).

Archives of Virology
Hepacivirus is a genus of RNA viruses within the family Flaviviridae of which hepatitis C virus (HCV) is the prototype. Several hepaciviruses have been identified in mammals, including rodents of multiple families. Each rodent hepacivirus described so far has been found only in members of a single rodent species.
G. E. Birlem, Alexandre Sita, J. S. Gularte, Deivid de Souza da Silva, M. Demoliner, P. R. de Almeida, J. D. Fleck, F. Spilki, Severino Silvano dos Santos Higino, S. S. de Azevedo, M. N. Weber   +10 more
semanticscholar   +3 more sources

Concerted synergy between viral-specific IgG and CD8+ T cells is critical for clearance of an HCV-related rodent hepacivirus

Hepatology
Background and Aims: Evidence assessing the role of B cells and their antibodies, or lack thereof, in the spontaneous resolution of acute HCV infection is conflicting.
John Gridley, Brantley Holland, E. Salinas, Sheetal Trivedi, Piyush Dravid, Elizabeth J. Elrod, Fengzhi Jin, Anuradha Kumari, Maria Batista, Manoj Thapa, Charles M. Rice, Joseph Marcotrigiano, Amit Kapoor, A. Grakoui   +13 more
semanticscholar   +1 more source

Highly divergent cattle hepacivirus N in Southern Brazil

Archives of Virology, 2019
The genus Hepacivirus includes 14 species (Hepacivirus A-N). In this study, we determined a partial genome sequence of a highly divergent bovine hepacivirus (hepacivirus N, HNV) isolate from cattle in Southern Brazil. Previously described HNV isolates have shared 80-99.7% nucleotide sequence identity in the NS3 coding region.
A. C. S. Mósena, Fabiana Quoos Mayer, L. F. Baumbach, Ana Varela, Matheus Nunes Weber, Samuel Paulo Cibulski, M. S. da Silva, Raíssa Canova, Renata da Fontoura Budaszewski, Cláudio Wageck Canal   +9 more
openaire   +3 more sources

Hepacivirus cross-species transmission and the origins of the hepatitis C virus

Current Opinion in Virology, 2016
Just 5 years ago the hepatitis C virus (HCV) - a major cause of liver disease infecting >3% of people worldwide - was the sole confirmed member of the Hepacivirus genus. Since then, genetically-diverse hepaciviruses have been isolated from bats, dogs, cows, horses, primates and rodents.
Pybus, Oliver G., Thézé, Julien
openaire   +4 more sources

Protection of Novel Adenovirus Vectored Vaccine in Rats Against Wild‐Type Hepacivirus and Variant Infections

Liver international (Print)
Hepatitis C virus (HCV) vaccines are urgently needed to achieve WHO's goal for the elimination of viral hepatitis by 2030. The lack of suitable animal models for evaluating vaccine efficacy has greatly hindered the development of HCV vaccines.
S. Luo, Qitao Deng, C. Liang, Panli Zhang, Peng Zou, Shikai Deng, Meng Zhang, Feifeng Zeng, Ling Zhang, Yongshui Fu, Chengyao Li, Tingting Li   +11 more
semanticscholar   +1 more source

Presence of two different bovine hepacivirus clusters in Germany

Transboundary and Emerging Diseases, 2018
During the last years, genetic information of hepaciviruses (family Flaviviridae), whose type species is the human hepatitis C virus, was detected in a wide range of primates and non-primate vertebrates. Here, samples collected from 263 German cattle kept in 22 different holdings were analysed for the presence of hepacivirus N (syn. bovine hepacivirus;
Kore Schlottau, Kerstin Wernike, Leonie Forth, Mark Holsteg, Dirk Höper, Martin Beer, Bernd Hoffmann   +6 more
openaire   +2 more sources