Results 121 to 130 of about 724,197 (388)
Formation of Condition‐Dependent Alpha‐Synuclein Fibril Strain in Artificial Cerebrospinal Fluid
Advanced Science, EarlyView.α‐synuclein aggregation in artificial cerebrospinal fluid (aCSF) leads to a distinct conformation with an electron density pocket motif found in aggregates from PD and MSA patients. Such fibrils has low stability outside the reaction conditions, hinting about the influence of cerebrospinal fluid components not only on the formation, but also on the ...
Rūta Sniečkutė +7 more
wiley +1 more source
Life-threatening hemorrhage following subcutaneous heparin therapy
Therapeutics and Clinical Risk Management, 2008 Jana Hudcova, Daniel TalmorDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USAAbstract: Prophylactic administration of unfractionated heparin is a common practice in ...
Jana Hudcova, Daniel Talmor
doaj
Heparin releases newly synthesized cell surface-associated apolipoprotein E from HepG2 cells.
Journal of Lipid Research, 1993 Heparin significantly increased the amount of newly synthesized apolipoprotein E (apoE) released by HepG2 cells. Culturing cells in the presence of 10 micrograms/ml of heparin for 2-6 days caused a 1.3-fold (day 2) to 3-fold (day 6) increase of ...
M Lilly-Stauderman +3 more
doaj +1 more source
Heparin affinity purification of extracellular vesicles
Scientific Reports, 2015 Extracellular vesicles (EVs) are lipid membrane vesicles released by cells. They carry active biomolecules including DNA, RNA and protein which can be transferred to recipient cells. Isolation and purification of EVs from culture cell media and biofluids
L. Balaj +7 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen +11 more
wiley +1 more source
Randomized phase III trial of low-molecular-weight heparin enoxaparin in addition to standard treatment in small-cell lung cancer: the RASTEN trial [PDF]
, 2017 L. Ek +9 more
openalex +1 more source
Advanced Science, EarlyView.After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin +6 more
wiley +1 more source
Journal of Lipid Research, 1994 Heparin is a well-known, widely used anticoagulant drug. In addition to its anticoagulant properties, however, it also has a marked influence on fat metabolism.
M Weintraub +8 more
doaj +1 more source
The significance of ACTH for the process of formation of complex heparin compounds in the blood during immobilization stress [PDF]
Adrenocorticotropin (ACTH) was administered to rats at different times following adrenalectomy. Adrenocorticotropin caused a significant increase in the formation of heparin complexes even in the absence of stress factor.
Kudryashov, B. A. +3 more
core +1 more source
Extensive Pulmonary Embolism in late pregnancy associated with Anticardiolipin Antibodies [PDF]
, 2004 The leading cause of morbidity and mortality during pregnancy and the puerperium is venous thromboembolism. Though uncommon, the risk is five times higher in a pregnant woman than in a non-pregnant woman of similar age.1,2 In pregnancy, all three ...
Brincat, Mark P. +5 more
core