Results 161 to 170 of about 724,197 (388)

The Comparative Study of Efficiency of Intravenous Heparin and Oral Aspirin on 48 Hours Beginning Primary Medication in Ischemic Stroke Patients

Journal of Rehabilitation, 2005
Objective: This study was done for comparing efficiency of Intravenous Heparin and Oral Aspirin among patients who had cerebral thrombi embolitic vascular accidents.
Ali Akbar Rezaei, Shahir Mazaheri, Saeed Bashirian, Nima Rezaei   +3 more
doaj  

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

Advanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal, Zilong Liu, Meera G. Nair, Juhong Chen   +3 more
wiley   +1 more source

Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer.

New England Journal of Medicine, 2003
Agnes Y. Y. Lee, M. Levine, R. Baker, C. Bowden, A. Kakkar, M. Prins, F. Rickles, J. Julian, S. Haley, M. Kovacs, M. Gent   +10 more
semanticscholar   +1 more source

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

End-point immobilization of heparin on plasma-treated surface of electrospun polycarbonate-urethane vascular graft

, 2017
Xuefeng Qiu, Benjamin Li-Ping Lee, Xinghai Ning, Niren Murthy, Nianguo Dong, Li Song   +5 more
openalex   +1 more source

High-affinity binding sites for heparin generated on leukocytes during apoptosis arise from nuclear structures segregated during cell death [PDF]

, 2002
Milena A. Gebska
openalex   +1 more source

Repeated in situ arterial thrombolysis in severe heparin-induced thrombocytopenia

, 2023
Roxane Varone, Daniel Danzer
openalex   +1 more source

Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin.

New England Journal of Medicine, 1995
T. Warkentin, Mark Levine, J. Hirsh, P. Horsewood, R. Roberts, M. Gent, J. Kelton   +6 more
semanticscholar   +1 more source

Microfluidic Electrochemical Biosensor for the Detection of Platelet Factor 4 Antibody‐Mediated Thrombotic Disorders

Advanced Science, EarlyView.
A microfluidic electrochemical biosensor enables sensitive and specific detection of antibodies associated with vaccine‐induced immune thrombotic thrombocytopenia (VITT) and heparin‐induced thrombocytopenia (HIT). The platform uses two antigen targets— platelet factor 4 (PF4) and cross‐linked‐PF4 (c‐PF4)—and microliter volumes of patient sera to ...
Diana F. Cedillo‐Alcantar, Adam Kanack, Seonhwa Lee, Alan M. Gonzalez‐Suarez, Kihak Gwon, Emily Mauch, Thi Thanh‐Qui Nguyen, Anand Padmanabhan, Alexander Revzin   +8 more
wiley   +1 more source

Biomedical applications of engineered heparin-based materials

Bioactive Materials
Heparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic backbone. Due to its fascinating chemical and physical properties, nontoxicity, biocompatibility, and biodegradability, heparin has been extensively used in ...
Ehsan Nazarzadeh Zare, Danial Khorsandi, Atefeh Zarepour, Hulya Yilmaz, Tarun Agarwal, Sara Hooshmand, Reza Mohammadinejad, Fatma Ozdemir, Onur Sahin, Sevin Adiguzel, Haroon Khan, Ali Zarrabi, Esmaeel Sharifi, Arun Kumar, Ebrahim Mostafavi, Negar Hosseinzadeh Kouchehbaghi, Virgilio Mattoli, Feng Zhang, Vadim Jucaud, Alireza Hassani Najafabadi, Ali Khademhosseini   +20 more
doaj   +1 more source