Results 251 to 260 of about 1,094,334 (317)

Metabolic Dysfunction-Associated Steatotic Liver Disease in Adults With Acromegaly: A Meta-Analysis of Observational Studies. [PDF]

Diabetes Metab Res Rev
Mantovani A, Morandin R, Molinaroli E, Messetti D, Rolli N, Forti M, Zoco M, Polyzos SA, Targher G.   +8 more
europepmc   +1 more source

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

Advanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang, Meng‐Meng Liu, Yu‐Chen Zhao, Jia‐Yi Li, Wen Li, Xin Yu   +5 more
wiley   +1 more source

Hepatocellular Carcinoma Arising From Well-Differentiated Hepatocellular Neoplasm of Uncertain Malignant Potential in a Patient With Abernethy Malformation. [PDF]

Case Rep Surg
Kinowaki K, Birkness-Gartman JE, Kamel I, Chu L, Anders RA, Shubert CR, Oshima K.   +6 more
europepmc   +1 more source

Beyond mismatch repair in colorectal cancer liver metastases: rethinking immunotherapy through the hepatic metastatic niche. [PDF]

Front Immunol
Yang L, Liang Y, Wang W, Li J, Jia B, Fu M, Xie X, Chen Q.   +7 more
europepmc   +1 more source

Branched-Chain Amino Acid Supplementation Exerts Opposite Effects on Offspring Growth and Differentially Affects Maternal Glucose and Lipid Metabolism in Lactating Dams Fed Normal- or Low-Protein Diets. [PDF]

Nutrients
Li X, Lin X, Feng L, Hu Z, Hou Q, Wang Y, Shen Y, Mu Y, Wang Z.   +8 more
europepmc   +1 more source

Age-Related Patterns of Organ-Specific Iron Distribution in Non-Transfusion-Dependent Thalassemia: A Multicenter MRI Study. [PDF]

J Clin Med
Meloni A, Pistoia L, Ricchi P, Longo F, Torti L, Cecinati V, Corigliano E, Zerbini M, Barbuto L, Fina P, Renne S, Positano V, Barison A.   +12 more
europepmc   +1 more source

Low-dose l-carnitine supplementation attenuates hepatic lipid accumulation in chow-fed mice: Insights from integrated multi-omics analysis. [PDF]

Food Chem (Oxf)
Zhang Z, Ding B, Zhang L, Zhang L, Huang Y.   +4 more
europepmc   +1 more source

Lipid Metabolic Reprogramming and Bioactive Lipid Signaling in MASLD: Molecular Mechanisms, Pathogenesis and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Ábel T, Csobod Csajbókné É.
europepmc   +1 more source