Results 161 to 170 of about 63,974 (267)

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Robotic single-port plus one-port radical cholecystectomy: description of surgical techniques with video. [PDF]

J Minim Invasive Surg
Kim SH, Jeong JH, Kang CM.
europepmc   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Acute cholecystitis in an intrahepatic duplicated gallbladder mimicking a liver abscess: The pivotal diagnostic role of percutaneous drainage. [PDF]

Radiol Case Rep
Kato A, Wada S, Song J, Morimoto K, Suzuki T, Hashimoto K, Fujikawa A, Morimoto T, Mimura H.   +8 more
europepmc   +1 more source

Endoscopic ultrasound-guided hepaticogastrostomy with antegrade and bridging stenting for diffusely extending cholangiocarcinoma. [PDF]

Endoscopy
Nishikawa T, Morii S.
europepmc   +1 more source

The Impact of Prehabilitation on Clinical Outcomes in Liver Surgery: A Systematic Review and Meta‐Analysis

World Journal of Surgery, EarlyView.
Major liver surgery is associated with significant physiological stress and a high rate of postoperative complications. Prehabilitation aims to enhance physiological reserve before surgery. Despite the growing volume of liver resections worldwide, the impact of prehabilitation on clinical and economic outcomes in patients undergoing elective liver ...
Lyrics M. Noba, Robyn J. Stiger, Declan F. J. Dunne, Lawrence D. Hayes, Christopher J. Gaffney, Ramani S. Moonesinghe, Ewen M. Harrison   +6 more
wiley   +1 more source

Spontaneous bilateral subcapsular hepatic hematoma following open cholecystectomy and common bile duct exploration: a rare and life-threatening postoperative complication. [PDF]

BMC Surg
Yasin NA, Jubur AA, Osman AA, Kulle BM, Ahmed AA, Hassan AI.   +5 more
europepmc   +1 more source

[A case of carcinoid tumor of the common hepatic duct].

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1989
YOSHIDA, Naoya, UENO, Yukihisa, SUMINO, Yasukiyo, WAKABAYASHI, Miyoji, ATOBE, Toshihiko   +4 more
openaire   +2 more sources

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Laparoscopic Transcystic Common Bile Duct Exploration for the Treatment of Choledocholithiasis Following Roux-en-Y Gastric Bypass. [PDF]

Obes Surg
Moyer ED, Quattrone M, Rothka AJ, Sodomin E, Pauli EM, Winder JS.   +5 more
europepmc   +1 more source