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Neurologic Clinics, 2002
Many patients with cirrhosis of the liver who appear to be overtly normal, using standard bedside examination techniques, test in the impaired range on one or more neuropsychological tests. These impairments affect the quality of life. Improvement in affected cognitive domains and the quality of life may follow the institution of treatment.
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Many patients with cirrhosis of the liver who appear to be overtly normal, using standard bedside examination techniques, test in the impaired range on one or more neuropsychological tests. These impairments affect the quality of life. Improvement in affected cognitive domains and the quality of life may follow the institution of treatment.
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Medical Clinics of North America, 1989
Hepatic encephalopathy (HE) is a complex reversible syndrome that can progress to coma. Recently, behavioral and electrophysiologic ameliorations of HE have been reported to occur in animal models of fulminant hepatic failure (FHF) and, in uncontrolled studies, in a majority of patients with FHF or cirrhosis following the intravenous administration of ...
S H, Gammal, E A, Jones
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Hepatic encephalopathy (HE) is a complex reversible syndrome that can progress to coma. Recently, behavioral and electrophysiologic ameliorations of HE have been reported to occur in animal models of fulminant hepatic failure (FHF) and, in uncontrolled studies, in a majority of patients with FHF or cirrhosis following the intravenous administration of ...
S H, Gammal, E A, Jones
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2011
Hepatic encephalopathy (HE) is a neuropsychiatric syndrome which can develop in the course of chronic and acute liver disease. It is characterized by cognitive and motoric deficits of varying severity. HE is functional in nature, potentially reversible and is thought to reflect the clinical manifestation of a low-grade cerebral edema, which exacerbates
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Hepatic encephalopathy (HE) is a neuropsychiatric syndrome which can develop in the course of chronic and acute liver disease. It is characterized by cognitive and motoric deficits of varying severity. HE is functional in nature, potentially reversible and is thought to reflect the clinical manifestation of a low-grade cerebral edema, which exacerbates
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Journal of Gastroenterology and Hepatology, 1993
The approach to the management of patients with HE is summarized in Table 3. Other diagnoses need to be excluded and, after a diagnosis of HE is made on clinical and possibly electroencephalographic grounds, a search made for precipitants. Sedatives and opiates should be avoided, and steps taken to avoid hypoglycaemia, fluid overload or electrolyte ...
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The approach to the management of patients with HE is summarized in Table 3. Other diagnoses need to be excluded and, after a diagnosis of HE is made on clinical and possibly electroencephalographic grounds, a search made for precipitants. Sedatives and opiates should be avoided, and steps taken to avoid hypoglycaemia, fluid overload or electrolyte ...
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Hepatic encephalopathy for the hospitalist
Journal of Hospital Medicine, 2016The care of patients with advanced liver disease is often complicated by episodes of acute decline in alertness and cognition, termed hepatic encephalopathy (HE). Hospitalists must be familiar with HE, as it is a common reason for hospitalization in this population and is associated with significantly increased mortality.
Joseph R, Sweigart +2 more
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Pharmacotherapy for Hepatic Encephalopathy
Drugs, 2010Hepatic encephalopathy (HE) is a challenging clinical complication of liver dysfunction with a wide spectrum of neuropsychiatric abnormalities that range from mild disturbances in cognitive function and consciousness to coma and death. The pathogenesis of HE in cirrhosis is complex and multifactorial, but a key role is thought to be played by ...
Paula V, Phongsamran +3 more
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Minimal hepatic encephalopathy
Indian Journal of Gastroenterology, 2009Minimal hepatic encephalopathy (MHE) is the mildest form of spectrum of hepatic encephalopathy (HE). Patients with MHE have no recognizable clinical symptoms of HE but have mild cognitive and psychomotor deficits. The prevalence of MHE is high in patients with cirrhosis of liver and varies between 30% and 84%; it is higher in patients with poor liver ...
Radha K, Dhiman, Yogesh K, Chawla
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Neuroimaging in hepatic encephalopathy
Clinical Gastroenterology and Hepatology, 2005Hepatic encephalopathy (HE) is a poorly defined, complex neuropsychological disorder that often accompanies portal hypertension. Although the mechanisms underlining HE and the characterization of HE are still under investigation, the information derived from functional neuroimaging of patients with HE complemented by laboratory investigation and ...
Charmaine A, Stewart +3 more
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Inflammation and hepatic encephalopathy
Archives of Biochemistry and Biophysics, 2013Hepatic encephalopathy (HE) is a neuropsychiatric syndrome associated with both acute and chronic liver dysfunction, spanning a spectrum that ranges from mild neuropsychological disturbances to coma. The central role of ammonia in the pathogenesis of HE remains incontrovertible however, there is a robust evidence base indicating the important role of ...
Coltart, Iona +2 more
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The pathophysiology of hepatic encephalopathy
Nursing in Critical Care, 2006AbstractHepatic encephalopathy (HE) is a complicated disorder, the pathophysiology of which remains to be fully understood. This article reviews the current main theories including the potential involvement of ammonia, γ‐aminobutyric acid (GABA)/benzodiazipines and false neurotransmitters.
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