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Nature Reviews Disease Primers, 2022 Hepatic encephalopathy (HE) is a prognostically relevant neuropsychiatric syndrome that occurs in the course of acute or chronic liver disease. Besides ascites and variceal bleeding, it is the most serious complication of decompensated liver cirrhosis.
Dieter Häussinger +11 more
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The Saudi Journal of Gastroenterology, 2012 Chronic liver disease and cirrhosis affect hundreds of millions of patients all over the world. The majority of patients with cirrhosis will eventually develop complications related to portal hypertension.
Wissam Bleibel, Abdullah M. S. Al-Osaimi
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Pathogenesis of Hepatic Encephalopathy [PDF]
Gastroenterology Research and Practice, 2012 Hepatic encephalopathy can be a serious complication of acute liver failure and chronic liver diseases, predominantly liver cirrhosis. Hyperammonemia plays the most important role in the pathogenesis of hepatic encephalopathy.
Irena Ciećko-Michalska +3 more
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Neurology, 1993 The approach to the management of patients with HE is summarized in Table 3. Other diagnoses need to be excluded and, after a diagnosis of HE is made on clinical and possibly electroencephalographic grounds, a search made for precipitants. Sedatives and opiates should be avoided, and steps taken to avoid hypoglycaemia, fluid overload or electrolyte ...
Harold O. Conn
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Management of hepatic encephalopathy. [PDF]
Journal of Gastroenterology and Hepatology, 1981 Abstract Hepatic encephalopathy (HE) is seen as a clinical manifestation of low grade chronic cerebral edema, which is accompanied by alterations in glioneural communication. Different factors such as ammonia, inflammatory cytokines, benzodiazepines and electrolyte imbalances may precipitate or aggravate glia edema, thereby explaining precipitation of
Dieter Häussinger, Gerald Kircheis
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Hepatic encephalopathy: A review
Annals of Hepatology, 2003 Hepatic encephalopathy (HE) is a complication that presents in as many as 28% of patients with cirrhosis, and reported up to ten years after the diagnosis of cirrhosis. Commonly, it is observed in patients with severe hepatic failure and is characterized
Javier Lizardi-Cervera, MD +3 more
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DMW - Deutsche Medizinische Wochenschrift, 2001 Hepatic encephalopathy (HE) is a reversible syndrome of impaired brain function occurring in patients with advanced liver diseases. The precise pathophysiology of HE is still under discussion; the leading hypothesis focus on the role of neurotoxins, impaired neurotransmission due to metabolic changes in liver failure, changes in brain energy metabolism,
Srinivasan Dasarathy, Kevin D. Mullen
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Portosystemic shunts and refractory hepatic encephalopathy: patient selection and current options
Hepatic Medicine: Evidence and Research, 2019 Cyriac Abby Philips, Sasidharan Rajesh, Philip Augustine, Guruprasad Padsalgi, Rizwan Ahamed The Liver Unit, Cochin Gastroenterology Group, Ernakulam Medical Centre, Cochin, Kerala, India Abstract: Portosystemic shunt (PS) syndrome encompasses a spectrum
Philips CA +4 more
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Diagnostics, 2022 Hyperintensities within the bilateral globus pallidus on T1-weighted magnetic resonance images were present in some liver cirrhosis patients with hepatic encephalopathy. The symptoms of covert hepatic encephalopathy are similar to those of mild dementia.
Yasuyuki Tamai +8 more
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