Results 171 to 180 of about 669,725 (291)

Interleukin‐1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis

Advanced Science, EarlyView.
During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum, Shenja Buchholz, Hanna Schifter, Sabine Ameling, Leif Steil, Ben Lewin Becker, Elke Hammer, Georg Homuth, Uwe Völker, Barbara M. Bröker, Lukas Zierke, Frank Ulrich Weiss, Juliane Glaubitz, Matthias Sendler   +13 more
wiley   +1 more source

Non-invasive assessment of hepatic fibrosis in pediatric survivors of acute lymphoblastic leukemia: a cross-sectional study. [PDF]

Eur J Pediatr
Sherief LM, Almalky MA, Bayoumi SS, Salah HE, Soliman BK, Kamal NM, Talaat SM, Sherbiny HS, Alsufyani AD, Alosaimi FS, Abdallah EAA.   +10 more
europepmc   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

Assessment of hepatic fibrosis in Egyptian children and adolescents with beta thalassemia major: a single center study. [PDF]

Eur J Pediatr
Elhady MA, Kaddah M, Marzouk A, Mogahed EA, Yassin NA.   +4 more
europepmc   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

HEPATIC FIBROSIS

Clinics in Liver Disease, 2001
Efsevia Albanis, Scott L. Friedman
openaire   +3 more sources

From diet to disease modulation: the multi-targeted effects of medicinal-food homologous plants in hepatic fibrosis. [PDF]

Front Nutr
Chen S, Chen H, Xie J, Peng X, Yang S, Yin D, Zhu Y.   +6 more
europepmc   +1 more source

[Pathophysiology of hepatic fibrosis].

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1999
MURAWAKI, Yoshikazu, KAWASAKI, Hironaka
openaire   +2 more sources

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Association of Life's Essential 8 with Hepatic Fibrosis, MASLD, and MetALD in the Framingham Heart Study. [PDF]

Nutrients
Campos A, Liu T, Prescott B, Ma J, Haff MG, Walker ME, Mohanty A, Xanthakis V.   +7 more
europepmc   +1 more source