Results 91 to 100 of about 113,972 (304)

First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI) [PDF]

, 2012
The objective of this pilot clinical study was to assess the safety, technical feasibility, pharmacokinetic (PK) profile and tumour response of DC Bead™ with irinotecan (DEBIRI™) delivered by intra-arterial embolisation for the treatment of metastatic ...
Hammerstingl, Renate Maria, Mack, Martin G., Gallus, Christof, Eichler, Katrin, Gruber-Rouh, Tatjana, Vogl, Thomas J., Zangos, Stephan   +6 more
core   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

Liver resection at the time of secondary cytoreduction in ovarian cancer

Gynecologic Oncology Reports
Background: Hepatic involvement in recurrent ovarian cancer has historically been considered a relative contraindication to cytoreductive surgery. Advances in hepatobiliary surgery and multidisciplinary collaboration have expanded the role of liver ...
Christina Harlev, Lindsey Finch, Dennis S. Chi, William R. Jarnagin, Kevin Soares   +4 more
doaj   +1 more source

Hepatic resection is associated with reduced postoperative opioid requirement

Journal of Anaesthesiology Clinical Pharmacology, 2016
Background and Aims: Postoperative pain can significantly affect surgical outcomes. As opioid metabolism is liver-dependent, any reduction in hepatic volume can lead to increased opioid concentrations in the blood.
Caitlyn Rose Moss, Julia Christine Caldwell, Babatunde Afilaka, Khaled Iskandarani, Vernon Michael Chinchilli, Patrick McQuillan, Amanda Beth Cooper, Niraj Gusani, Dmitri Bezinover   +8 more
doaj   +1 more source

Molecular imaging using positron emission tomography in gastrointestinal malignancy [PDF]

, 2010
Positron Emission Tomography (PET) with 18F-FDG has emerged as a powerful tool in oncology. Furthermore, recent advent of PET/CT and novel tracers are continually expanding its role.
Pakzad, F.
core  

Lymph Node Metastasis Pattern and Influencing Factors in Esophageal Squamous Cell Carcinoma

AGING MEDICINE, EarlyView.
Among 388 patients with esophageal squamous cell carcinoma who underwent curative resection, 144 (37.1%) developed lymph node metastasis. Upper thoracic tumors mainly involved upper mediastinal and upper right paratracheal nodes, whereas lower thoracic tumors more often involved paracardial and abdominal nodes.
Yuheng Wang, Qingqing Ding, Lei Xue, Jinhua Luo   +3 more
wiley   +1 more source

Recurrent Hepatic Sarcomatoid Carcinoma Cured by Doxorubicin and Ifosfamide Chemotherapy

Journal of Cancer Research and Practice, 2015
Hepatic sarcomatoid carcinoma is a rare malignant neoplasm composed of both carcinomatous and sarcomatous components. It has a higher risk of relapse and distant metastasis compared with ordinary hepatocellular carcinoma despite of radical resection.
Ming-En Lin, Huai-Cheng Huang
doaj   +1 more source

Recent Advances in Functional Liver Volumetry: Emphasis on 99mTc‐GSA SPECT/CT Fusion Imaging

Annals of Gastroenterological Surgery, EarlyView.
Functional liver volumetry enables more accurate assessment of the future liver remnant by integrating anatomical and functional information, improving risk stratification before major hepatectomy. Among available techniques, 99mTc‐GSA SPECT/CT fusion imaging enables precise regional functional assessment and more reliable prediction of post ...
Toru Beppu, Toshiro Masuda, Yasunori Nagayama, Hidetoshi Nitta, Hiromitsu Hayashi   +4 more
wiley   +1 more source

Oncological outcomes after hepatic resection and/or surgical microwave ablation for liver metastasis from gastric cancer

Asian Journal of Surgery, 2019
Summary: Background: Indications and efficacy of surgical treatment for liver metastases from gastric cancer (LMGCs) remain controversial. This retrospective study was designed to clarify the benefits of surgical treatment and identify prognostic ...
Tomoki Ryu, Yuko Takami, Yoshiyuki Wada, Masaki Tateishi, Hajime Matsushima, Munehiro Yoshitomi, Hideki Saitsu   +6 more
doaj   +1 more source

Hepatic resection for hepatocellular carcinoma [PDF]

, 2018
Hepatic resection has become the standard treatment of primary liver cancer. Indications for hepatic resection in patients with hepatocellular carcinoma (HCC) vary greatly between Japan and other countries because the clinical practice guidelines for HCC
Yamaguchi, Shun, Kosaka, Taichiro, Eguchi, Susumu   +2 more
core