Results 101 to 110 of about 69,340 (246)

Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The current study found no evidence of cumulative increased safety risks with upadacitinib 15 or 30 mg for up to 6 years and over 9000 patient‐years of safety data in adults and adolescents. There were low rates of adjudicated major adverse cardiovascular events, adjudicated thromboembolic events and malignancies. Abstract Background Atopic dermatitis (
Christopher G. Bunick, Alan D. Irvine, Jonathan I. Silverberg, Emma Guttman‐Yassky, Mona Shahriari, Xinghua Gao, Stephan Weidinger, Norito Katoh, Namita Vigna, Deanne M. Dilley, Elvira D'Andrea, Henrique D. Teixeira, Andrew M. Platt, Gweneth F. Levy   +13 more
wiley   +1 more source

Iron Regulation in Elderly Asian Elephants (Elephas maximus) Chronically Infected With Mycobacterium tuberculosis

Frontiers in Veterinary Science, 2020
Restriction of nutrients to pathogens (nutritional immunity) is a critical innate immune response mechanism that operates when pathogens such as Mycobacterium tuberculosis have the potential to evade humoral immunity.
Maja Ruetten, Hanspeter W. Steinmetz, Markus Thiersch, Marja Kik, Lloyd Vaughan, Sandro Altamura, Martina U. Muckenthaler, Martina U. Muckenthaler, Martina U. Muckenthaler, Max Gassmann, Max Gassmann   +10 more
doaj   +1 more source

Management of bacterial infection in the liver transplant candidate [PDF]

, 2018
Bacterial infection (BI) is a common cause of impairment of liver function in patients with cirrhosis, especially in the liver transplant candidates. These patients share an immunocompromised state and increased susceptibility to develop community and ...
Becchetti, Chiara, Burra, Patrizia, Ferrarese, Alberto, Gambato, Martina, Germani, Giacomo, Russo, Francesco Paolo, Sciarrone, SALVATORE STEFANO, Senzolo, Marco, Shalaby, Sarah, Zanetto, Alberto   +9 more
core   +1 more source

Bimekizumab efficacy and safety in Chinese patients with psoriasis in the BE SHINING Phase 3 study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In Chinese patients with moderate to severe plaque psoriasis, bimekizumab treatment was well tolerated and led to significantly higher clinical response rates versus placebo, including complete skin clearance. These findings were consistent with global studies and suggest that bimekizumab is an effective treatment option for Chinese people living with ...
Lin Cai, Xiao‐Yong Man, Jinyan Wang, Aihua Wei, Ying Chen, Delphine Deherder, Jun Gao, Bengt Hoepken, Weiwei Sun, Tingting Lei, Jianzhong Zhang, the BE SHINING Study Group   +11 more
wiley   +1 more source

Case report on serohepatic tuberculosis (frosted liver): Clinical presentation, imaging, diagnosis, and management

Radiology Case Reports
Hepatic tuberculosis can manifest in various forms, including parenchymal, serohepatic, tuberculous cholangitis and mixed form. Isolated hepatic tuberculosis, specifically in the form of serohepatic tuberculosis, is very rare.
Prajwal Dahal, MD, Alina Awale, MD, Sabina Parajuli, MBBS   +2 more
doaj   +1 more source

Long‐Term Efficacy of Arthroscopic Microfracture Combined With Autologous Collagen‐Induced Chondrogenesis for Knee Cartilage Defects: A 5‐Year Prospective Pilot Randomized Controlled Trial

Orthopaedic Surgery, EarlyView.
Arthroscopic microfracture combined with autologous collagen‐induced chondrogenesis provides superior long‐term cartilage regeneration and sustained clinical improvement in knee cartilage defects, as evidenced by 5‐year MRI and functional outcomes. ABSTRACT Objectives Cartilage defect of the knee joint is a common cause of knee pain and can result in ...
Shuofang Ren, Zhuosong Bai, Xin Lu, Yan Zhang, Xu Sun, Rui Tang, Bo Yang, Jun Qian, Guixing Qiu   +8 more
wiley   +1 more source

Granulomatous liver diseases: A review

Journal of the Formosan Medical Association, 2012
Granulomas that consist of focal accumulations of macrophages are commonly found in the liver due to stimulation of the immune system by a number of agents.
Marcy Coash, Faripour Forouhar, Catherine H. Wu, George Y. Wu   +3 more
doaj   +1 more source

Therapeutic Strategies and Clinical Outcomes of Infections Following Anterior Cruciate Ligament Reconstruction: A Narrative Review

Orthopaedic Surgery, EarlyView.
ACL reconstruction‐associated infections threaten graft integrity and joint function. This review summarizes patient‐related risk factors, approaches, and treatment strategies, with emphasis on early recognition and preventive measures such as vancomycin presoaking.
Shaoli Zhang, Jue Gong
wiley   +1 more source

Detection of Mycobacterium tuberculosis in a patient with suspected cystic echinococcosis: a case report

Journal of Medical Case Reports
Background Tuberculosis is a global health issue affecting millions of people worldwide. While pulmonary tuberculosis is common, hepatic tuberculosis is rare and accounts for less than 1% of cases.
Simon Daller, Julian Frederic Hotz, Moritz Staudacher, Polina Kalinina, Susanna Lang, Fredrik Waneck, Heimo Lagler   +6 more
doaj   +1 more source

Persistent Hyperglycaemia and Transient Dysglycaemia in Tuberculosis: Evaluating the Bidirectional Interaction With Type‐2 Diabetes Mellitus and Clinical Outcomes

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Poor glycaemic control, indicated by a haemoglobin A1c (HbA1c) level of 7% or higher, increases the risk of active tuberculosis (TB) in patients with diabetes, while active TB can worsen glucose tolerance and insulin resistance, contributing to type‐2 diabetes mellitus (DM) progression.
Augustine Asare Boadu, Prince Asare, Michelle Yeboah‐Manu, Stephen Osei‐Wusu, Emelia Danso Konadu, Adwoa Asante‐Poku, Yayra Klinogo, Abraham Adjei, Desmond Omane Acheampong, Jane S. Afriyie‐Mensah, Dorothy Yeboah‐Manu, Yacoba Atiase   +11 more
wiley   +1 more source