Results 101 to 110 of about 70,271 (233)

Mavrilimumab, a fully human granulocyte-macrophage colony-stimulating factor receptor α monoclonal antibody: long-term safety and efficacy in patients with rheumatoid arthritis [PDF]

, 2018
Objective: Mavrilimumab, a human monoclonal antibody, targets granulocyte-macrophage colony-stimulating factor receptor alpha. We report mavrilimumab long-term safety and efficacy in rheumatoid arthritis patients in two phase IIb studies (1071, 1107 ...
Achuthan, Akagawa, Aletaha, Aletaha, Antoniu, Avci, Berghen, Borg, Borie, Brown, Buch, Burmester, Burmester, Calisto, Cella, Chen, Cook, Cornish, Cottin, Crotti, Dawson, Felson, Fleetwood, Fries, Greven, Guo, Hamilton, Jaguin, Kelly, Khan, Lazaro, Listing, Minter, Prevoo, Shaw, Shibata, Singh, Tsuchiya, Van der Heijde, Van Gestel, Van Onna, Ware, Weinblatt, Yoshida, Zhan   +44 more
core   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Iron Regulation in Elderly Asian Elephants (Elephas maximus) Chronically Infected With Mycobacterium tuberculosis

Frontiers in Veterinary Science, 2020
Restriction of nutrients to pathogens (nutritional immunity) is a critical innate immune response mechanism that operates when pathogens such as Mycobacterium tuberculosis have the potential to evade humoral immunity.
Maja Ruetten, Hanspeter W. Steinmetz, Markus Thiersch, Marja Kik, Lloyd Vaughan, Sandro Altamura, Martina U. Muckenthaler, Martina U. Muckenthaler, Martina U. Muckenthaler, Max Gassmann, Max Gassmann   +10 more
doaj   +1 more source

Antiretroviral treatment outcomes in patients who received rifampicin together with nevirapine or efavirenz. [PDF]

, 2008
Cape Town TB ...
Boulle, A, Cohen, Karen, Goemaere, Eric
core   +1 more source

Silymarin protects liver against toxic effects of anti-tuberculosis drugs in experimental animals [PDF]

, 2008
Background The first line anti-tuberculosis drugs isoniazid (INH), rifampicin (RIF) and pyrazinamide (PZA) continues to be the effective drugs in the treatment of tuberculosis, however, the use of these drugs is associated with toxic reactions in tissues,
Sude Eminzade, Fikriye Uras, Fikret V Izzettin, S Houston, GS Timmins, D Zimhony, Hong Kong Chest Service, Medical Research Counsil, Myambutol (Lederle), A Trevor, N Vuilleumier, BU Bradford, HG Jeong, Y Dai, JA Timbrel, SA Tasduq, CP Sodhi, R Pal, C Victorrajmohan, SV Rana, S Attri, FS Hogan, P Morazzoni, MR Adhvaryu, S Santhosh, Medical Research Council, SK Sharma, AK Bahri, R Pal, SA Tasduq, CP Sodhi, SA Tasduq, SM Meeran, K Raina   +32 more
core   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Case report on serohepatic tuberculosis (frosted liver): Clinical presentation, imaging, diagnosis, and management

Radiology Case Reports
Hepatic tuberculosis can manifest in various forms, including parenchymal, serohepatic, tuberculous cholangitis and mixed form. Isolated hepatic tuberculosis, specifically in the form of serohepatic tuberculosis, is very rare.
Prajwal Dahal, MD, Alina Awale, MD, Sabina Parajuli, MBBS   +2 more
doaj   +1 more source

Is ALT control really necessary for routine ART monitoring in resource poor settings? [PDF]

, 2006
2006 AIDS Conference in ...
di Mattei, P, Gregorio, D, Nguimfack, A, Sitoe, F, Toalha, B   +4 more
core   +1 more source

Contrast-enhanced ultrasonography in hepatosplenic sarcoidosis [PDF]

, 2011
We report a case of a 38-year-old woman with atypical pain in the left lower hemi-abdomen. On abdominal B-mode ultrasonography the liver was normal; the spleen showed multiple subcentimetric hypoechoic nodules.
Afschrift, Marcel, STRYCKERS, MARIJKE, Van Belle, Simon, Verstraete, Koenraad, Voet, Dirk, Vogelaers, Dirk   +5 more
core   +2 more sources

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, EarlyView.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadari, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source