Results 131 to 140 of about 70,271 (233)

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

open access: yeseFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam   +4 more
wiley   +1 more source

No relevant pharmacokinetic interaction between the KRAS G12C inhibitor sotorasib and the direct oral anticoagulant rivaroxaban in healthy subjects

open access: yesInternational Journal of Cancer, Volume 158, Issue 11, Page 2920-2927, 1 June 2026.
What's new? Venous thromboembolism (VTE) is common in cancer patients, with direct oral anticoagulants, including rivaroxaban, recommended as first‐line therapy. However, oral anticoagulant use is limited due to the growing use of targeted therapy and concerns about drug‐drug interactions.
Esther M. Hollander   +7 more
wiley   +1 more source

A Framework for Emergency Department–Integrated Hepatitis C Test‐and‐Treat in the United States

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 6, June 2026.
ABSTRACT Despite the availability of curative, direct‐acting antiviral therapy, hepatitis C virus elimination remains incomplete. Losses across the care cascade continue to limit impact, from initial diagnosis to sustained virologic response. Fewer than 1/3 of individuals ultimately achieve cure. These gaps reflect a delivery system that does not align
Saeed S. Graham
wiley   +1 more source

An Atypical Presentation of Tuberculous Ascites, Severe Hyponatremia, and Acute Kidney Injury in a Young Male

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A 25‐year‐old male who had been in good health before presenting with right lower lobe pneumonia, severe hyponatremia (Na 117 mEq/L), distension, and reduced urine output. AKI secondary to acute glomerulonephritis (GN) or interstitial nephritis was suggested by the initial workup. He was discharged for outpatient nephrology follow‐up following
Bassem Al Hariri   +5 more
wiley   +1 more source

Reassessing Discordant Exudative Pleural Effusion in Heart Failure: A Rare Case of Occult Malignancy Uncovered by Post‐Thoracentesis Tension Pneumothorax

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Pleural effusions can be manifestations of heart failure, pulmonary embolism, infection, and malignancy. Symptom assessment, imaging, and pleural fluid analysis serve as key determinants in guiding clinical management. We present the case of a 75‐year‐old woman with a history of heart failure who developed worsening dyspnea and lower extremity
Christ Ordookhanian   +3 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis in Gorgan, Iran (2007-12)

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Anti tuberculosis drugs therapy is the most effective method for controling the tuberculosis (TB). Early detection and appropriate treatment can prevent the TB-drug resistance.
Khodabakhshi B   +4 more
doaj  

Molecular Mechanisms of Resistance and Treatment Efficacy of Delamanid Against Mycobacterium tuberculosis: A Systematic Review

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Tuberculosis (TB) remains a major global health problem, and treatment progress is increasingly threatened by rising multidrug‐resistant tuberculosis (MDR‐TB). Delamanid (DLM), a nitroimidazole drug, has shown good efficacy and safety against both drug‐susceptible and drug‐resistant Mycobacterium tuberculosis (Mtb) strains.
Md. Mahmudul Islam   +19 more
wiley   +1 more source

Successful Management of Septic Splenitis in an Abyssinian Cat

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho   +10 more
wiley   +1 more source

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