Results 71 to 80 of about 548,757 (242)

Safety and Efficacy of Deucravacitinib in Japanese Patients With Moderate to Severe Plaque Psoriasis: 5‐Year Analysis of the Phase 3 POETYK PSO‐1, PSO‐4, and Long‐Term Extension Trials

The Journal of Dermatology, EarlyView.
ABSTRACT Deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, is approved in multiple countries for the treatment of moderate to severe plaque psoriasis, as well as generalized pustular and erythrodermic psoriasis in Japan. Deucravacitinib 6 mg once daily was efficacious and well tolerated through 3 years in the pooled population of ...
Yukari Okubo, Akimichi Morita, Yayoi Tada, Shinichi Imafuku, April W. Armstrong, Andrew Blauvelt, John Vaile, Zoran Popmihajlov, Janice Li, Rajesh Sawant, Katsuyoshi Habiro, Katsuki Tsuritani, Mamitaro Ohtsuki   +12 more
wiley   +1 more source

Hepatic tuberculosis mimicking Klatskin tumor: A diagnostic dilemma

Indian Journal of Pathology and Microbiology, 2008
Tubercular involvement of liver is rare and usually occurs in association with pulmonary or miliary tuberculosis, as diffuse involvement without recognizable pulmonary tuberculosis or rarely in a localized form, which presents as a tuberculoma or ...
Arora Raman, Sharma Alok, Bhowate Prashant, Bansal Vijender, Guleria Sandeep, Dinda Amit   +5 more
doaj  

Systemic Treatment of Psoriasis: Current Evidence on Efficacy and Safety

The Journal of Dermatology, EarlyView.
ABSTRACT Systemic treatments for moderate‐to‐severe plaque psoriasis have been advanced from broad immunosuppressants up to agents more selectively targeting cytokines, cytokine receptors, or intracellular signaling. The current systemic treatments mainly consist of conventional systemic agents, biologics targeting tumor necrosis factor (TNF)‐α ...
Teppei Hagino, Naoko Kanda
wiley   +1 more source

A tuberculosis directory, containing a list of institutions, associations and other agencies dealing with tuberculosis in the United States and Canada ...

, 1911
Compiler: 1911- P.P. Jacobs.Directory for 1919 issued in 3 parts: 1. A directory of tuberculosis associations and committees in the United States. 2. A directory of dispensaries, clinics and classes for the special treatment of tuberculosis in the United
Jacobs, Philip Peter, 1879- comp., National Tuberculosis Association.   +1 more
core  

Isolated liver tuberculosis

Bangabandhu Sheikh Mujib Medical University Journal, 2016
Isolated liver tuberculosis is still considered a rare condition and its atypical clinical presentation challenges the clinical acumen of the treating physician.
Ruksana Karim, Md. Mohsen Chowdhury, Arif Salam Khan   +2 more
doaj   +1 more source

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

Cell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang, Yucheng Gao, Shuhang Dong, Shuanggong Liu, Lei Liu, Ziyi Song, Jie Xu, Yijun Rong, Guangxu Song, Yingze Zhang, Dongjin Wu, Zengxin Gao   +11 more
wiley   +1 more source

The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gstm1 and gstt1. [PDF]

, 2014
BACKGROUND AND OBJECTIVE: Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1 ...
Ma, Jinfeng, Xuemei Yao, Mingqin Cao, Merle Corinne, Xia Zhu, Liu Wei, Weidong Wu, Yongguang Li, Jiayi Gu, Ma Jinfeng, Qian Wang, Milligan Paul, Zhu, Xia, Ying Mao, Liu, Wei, Ma Long, Jinfeng Ma, Xiang, Yang, Cao, Mingqin, Ma, Long, Merle, Corinne, Long Ma, Yang Lei, Xiang Yang, Yao Xuemei, Wubuli, Atikaimu, Wu, Weidong, Xin Xiumei, Li, Yongguang, Yang Xiang, Paul Milligan, Xiumei Xin, Lei Yang, Corinne Merle, Zhu Xia, Li Yongguang, Mao Ying, Milligan, Paul, Mao, Ying, Gu, Jiayi, Atikaimu Wubuli, Gu Jiayi, Yao, Xuemei, Wu Weidong, Wang Qian, Yang, Lei, Xin, Xiumei, Wang, Qian, Cao Mingqin, Wubuli Atikaimu, Wei Liu   +50 more
core   +1 more source

Self-study modules on tuberculosis 1-5 : Introduction [PDF]

Course #WB2556The Self-Study Modules on Tuberculosis is a series of educational modules designed to provide information about tuberculosis (TB) in a self-study format. The series consists of nine modules that are separated into two parts. The first part,

core   +1 more source

Tuberculosis hepática primaria como causa de fiebre de origen desconocido

Acta Médica Costarricense, 2007
Se presenta el caso de un paciente de 29 años de edad, quien se presentó con un cuadro de fiebre, sudoración nocturna y pérdida de peso, el que inicialmente fue catalogado como dengue clásico, pero que al persistir, fue abordado como fiebre de origen ...
Manuel Antonio Villalobos-Zúñiga, Júvel Quintanilla-Gallo, Charles Gourzong-Taylor   +2 more
doaj  

Associations between prior wasting malnutrition and indices of insulin secretion and sensitivity among six cohorts from Asia and Africa: The SAMPA study

Diabetic Medicine, EarlyView.
Abstract Aims The role of prior wasting malnutrition (PM) in determining insulin sensitivity and secretion in low‐ and middle‐income countries (LMICs) remains unclear. We investigated associations of insulin indices with PM and whether these were modified by current body mass index (BMI).
Sharon E. Cox, Sana Ahmed, Dixi Paglinawan Modoc, Riddhi Dasgupta, Christina Christoffersen, Molly Chisenga, Julius Patrick Ferrer, Ruth Frikke‐Schmidt, Rikke Krogh‐Madsen, Belinda Kweka, Nanette Lee, Evangelista Malindisa, Mizinga J. Tembo, Patrick Ngoya, Dorothea Nitsch, Daniel Faurholt‐Jepsen, George PrayGod, Geeta Trilok‐Kumar, Suzanne Filteau, James A. M. Shaw   +19 more
wiley   +1 more source