Results 211 to 220 of about 3,463,039 (240)
Lung‐Cardiovascular Interactions and Derangements in ARDS
Comprehensive Physiology, Volume 16, Issue 5, October 2026.This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez +4 more
wiley +1 more source
Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease
MedComm, Volume 7, Issue 10, October 2026.NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang +9 more
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.Here, we report that nuclear membrane CD63 (nmCD63), a marker of targeted nuclear degranulation in neutrophils, represents a novel biomarker for sepsis. In a two‐center prospective cohort with independent external validation, nmCD63 outperforms CRP and PCT for early sepsis diagnosis, with the nmCD63+SOFA combined model reaching an AUC of 0.943.
Xingxin Gao +7 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies
MedComm, Volume 7, Issue 10, October 2026.The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao +7 more
wiley +1 more source
Aging Cell, Volume 25, Issue 10, October 2026.Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley +1 more source
Aging Cell, Volume 25, Issue 10, October 2026.GFD‐CD3, a uPAR‐targeting T‐cell engager, effectively cleared senescent cells and mitigated age‐related pathologies with a favorable safety profile under transaminase‐guided monitoring. ABSTRACT Senolytic CAR‐T cells targeting uPAR induce dose‐dependent toxicities.
Jian Deng +13 more
wiley +1 more source
Life‐stage variation in Sable Shearwater (Ardenna carneipes) physiology assessed using proteomics
Ibis, Volume 168, Issue 4, Page 1500-1515, October 2026.Life‐stage transitions in seabirds involve substantial shifts in physiological demands, yet the molecular mechanisms underpinning these changes remain poorly resolved. Here we applied untargeted data‐independent acquisition mass spectrometry (DIA‐MS) to characterize and compare the plasma proteomes of fledgling and adult Sable Shearwaters Ardenna ...
Alix M. de Jersey +5 more
wiley +1 more source
Liver International, Volume 46, Issue 10, October 2026.ABSTRACT Background and Aims Assessing liver congestion and portal hypertension (PHT) in Budd–Chiari syndrome (BCS) remains challenging. We evaluated liver and spleen stiffness measurements (LSM, SSM) obtained by transient elastography as non‐invasive tools for identifying clinically meaningful liver congestion in BCS.
Andreea Fodor +22 more
wiley +1 more source
An Automated Microfluidic System for Haemostasis Assessment in Cirrhosis With Thrombocytopenia
Liver International, Volume 46, Issue 10, October 2026.ABSTRACT Background & Aims Conventional laboratory tests do not capture platelet–vessel wall interactions (primary haemostasis) occurring in vivo, limiting guidance before invasive procedures. This is relevant in patients with thrombocytopenia, hallmark of advanced cirrhosis. Microfluidic assays may overcome these limitations.
Niccolò Bitto +14 more
wiley +1 more source