Results 211 to 220 of about 415,200 (261)

Accuracy of non-invasive tests for diagnosing liver fibrosis and steatosis: A systematic review. [PDF]

World J Gastrointest Pathophysiol
Shukla SR, Baig MAA, Pareek A, Johari N, Thapa Y, Kumpati BB, Nirmal SM, Ayesha Imdad I, Azid D, Aina E, Lakhani A.   +10 more
europepmc   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Prevalence, Clinical Profiles, Disease Severity, and Patient Outcomes of Alcoholic Liver Disease in a Tertiary Care Hospital of Nepal. [PDF]

Health Sci Rep
Joshi B, Challa U, Aayush, Hernandez R, Devkota K, Yadav P, Dominguez RJR, Jawad A, Mateen MA, Dirani NA.   +9 more
europepmc   +1 more source

Impact of Single Viable Hepatocellular Carcinoma ≤ 3 cm on Survival After Liver Transplantation

ANZ Journal of Surgery, EarlyView.
An Australian multi‐centre cohort study shows significantly lower 5‐year HCC‐specific mortality for those with no viable disease compared to those with a single viable tumour ≤ 3 cm, on imaging prior to transplantation. A lower AFP level and complete response on mRECIST criteria also reduced risk.
Lauren C. Y. Tang, Eunice Lee, Avik Majumdar, Ted Stoklosa, Danny Con, William Chung, Emily Nash, Adam Testro, Michael Fink, Simone Strasser, Ken Liu, David G. Bowen, Marie Sinclair   +12 more
wiley   +1 more source

Cirrhosis Impairs Reconstitution of the Circulating T-Lymphocyte Compartment After Direct-Acting Antiviral Therapy for Hepatitis C Virus Infection. [PDF]

United European Gastroenterol J
Paule L, Castillo E, Muñoz L, Martínez J, Fernández C, Miranda A, Lario M, Monserrat J, Ortega MÁ, Calleja JL, Álvarez-Mon M, Albillos A.   +11 more
europepmc   +1 more source

Clinical Outcomes After Percutaneous Coronary Intervention in Patients With Cirrhosis: A Multicentre National Study

Alimentary Pharmacology &Therapeutics, EarlyView.
Summary of a multicentre TriNetX study evaluating outcomes after percutaneous coronary intervention (PCI) in patients with cirrhosis. Cirrhosis was associated with higher 1‐year gastrointestinal bleeding and mortality, especially with decompensated disease.
Dhir Gala, Sameer Rao, Manas Gunani, Kajol Shah, Anand V. Kulkarni, Karn Wijarnpreecha, Daniel Q. Huang, Pojsakorn Danpanichkul, Ahmed Al‐Khazraji, Kaveh Hajifathalian, Vivek Lingiah, Paul Gaglio, Nikki Duong, Christine Gerula   +13 more
wiley   +1 more source

Tiopronin-induced reversible bilateral parotid gland enlargement in a patient with alcoholic cirrhosis: Case report. [PDF]

Medicine (Baltimore)
Jiang S, Chen G, Kong L, Zhao H.
europepmc   +1 more source

Carriage of the Laboratory of Genetics and Physiology Protein 2 Q425R Variant Reduces Liver Disease Severity in European Patients With Chronic Hepatitis Delta

Alimentary Pharmacology &Therapeutics, EarlyView.
In patients with chronic hepatitis Delta, the LGP2 Q425R variant (rs2074158 CC/CT genotypes), associated with an enhanced interferon response in vitro, becomes progressively less frequent as liver disease advances from no cirrhosis to cirrhosis, and to cirrhosis with progressive increase of portal hypertension evaluated by thrombocytopenia.
Sara Cmet, Elisabetta Degasperi, Annarosa Cussigh, Elisabetta Fontanini, Maria Paola Anolli, Floriana Facchetti, Riccardo Perbellini, Dana Sambarino, Sara Uceda Renteria, Mariapaola Callegaro, Davide Bitetto, Elisa Fumolo, Ezio Fornasiere, Elena Garlatti Costa, Edmondo Falleti, Pietro Lampertico, Pierluigi Toniutto   +16 more
wiley   +1 more source

Associations between physical activity and dietary live microbe intake with non-alcoholic fatty liver disease: findings from the NHANES, 2007-2018. [PDF]

J Glob Health
Ding S, Hu X, Liu J.
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source