Results 221 to 230 of about 415,200 (261)

Liver disease diagnostics and access barriers in African settings: a narrative review. [PDF]

J Clin Pathol
Jagunmolu HA, Oyetola EO, Lawal YA, Akinsanya SO, Ibrahim MA, Idowu TO, Oyelude SO, Jubreel MA, Ajibade DO, Olaniyi TO, Sheriff AA.   +10 more
europepmc   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Serum immunoglobulin G levels in patients with cirrhosis due to autoimmune hepatitis or other etiologies. [PDF]

Eur J Gastroenterol Hepatol
Su Y, Wang Q, Sun X, Zhao X, Zhao X, Jia J, Shan S.   +6 more
europepmc   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Serum lipid profile as an indicator of disease severity in chronic liver disease: A hospital-based cross-sectional study. [PDF]

Bioinformation
Rangare V, Nagwanshi J, Raghuwanshi K.
europepmc   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source

Real‐World Cost and Utilisation Burden of Diagnosed Metabolic Dysfunction‐Associated Steatotic Liver Disease in Patients With Type 2 Diabetes in the United States: A Retrospective Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study quantified the real‐world healthcare costs and utilisation associated with diagnosed metabolic dysfunction‐associated steatotic liver disease (MASLD) among adults with Type 2 diabetes (T2D). Methods We conducted a retrospective cohort study using IQVIA PharMetrics Plus Closed Health Plan data from January 2016 to June 2025 ...
Tien Hoang Tran, Hyung‐Seok Kim, Rozalina G. McCoy, Zafar Zafari   +3 more
wiley   +1 more source

Dietary Isorhamnetin Alleviates Alcoholic Liver Injury in Mice by Regulating Gut Microbiota via the Gut-Liver Axis. [PDF]

Nutrients
Wu L, Bai Y, Su E, Cao F, Fang X, Zhao L.   +5 more
europepmc   +1 more source

Hand Hygiene Accuracy of Students and Staff at a Dutch Dental School

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Oral health care professionals continuously come into contact with bodily fluids containing many pathogens. Hand hygiene should be used to prevent cross transmission. We aimed to examine the accuracy of application of alcohol‐based hand rub (ABHR) according to the WHO hand hygiene steps at a dental school.
Ilona Francisca Persoon, Catherine Minke Charlotte Volgenant   +1 more
wiley   +1 more source