Results 101 to 110 of about 119,198,728 (316)

Immunogenicity and safety of the Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine co-administered with human rotavirus, hepatitis A and 13-valent pneumococcal conjugate vaccines: results from a phase III, randomized, multicenter study in infants

Human Vaccines & Immunotherapeutics, 2019
This phase III, open-label, randomized study (NCT01978093) evaluated the immunogenicity and safety of co-administered Haemophilus influenzae type b–Neisseria meningitidis serogroups C and Y–tetanus toxoid conjugate vaccine (Hib-MenCY-TT) with human ...
Nicola P. Klein, Remon Abu-Elyazeed, Yaela Baine, Brigitte Cheuvart, Marcela Silerova, Narcisa Mesaros   +5 more
doaj   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Hepatitis C : by the numbers [PDF]

Hepatitis C is among the deadliest infectious diseases in the United States. In 2019, approximately 14,242 death certificates listed hepatitis C as an underlying or contributing cause of death in the United States and the number of people newly infected ...

core  

Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency among the fulminant hepatitis A virus infection patients [PDF]

Caspian Journal of Internal Medicine
Background: Hepatitis A is a widespread viral infection with significant public health implications. Assessing glucose 6-phosphate dehydrogenase (G6PD) deficiency in hepatitis A patients is essential for various reasons, including prognosis, disease ...
Fardad Ejtehadi, Maryam Sadat Serpoosh, Iraj Shahramian, Ladan Aminlari, Ramin Niknam, Gholam Reza Sivandzadeh, Masoud Tahani, Amin Javadifar, Fateme Sharafi, Maryam Moini   +9 more
doaj  

Changing epidemiological characteristics of Hepatitis A and warning of Anti-HAV immunity in Beijing, China: a comparison of prevalence from 1990 to 2017

Human Vaccines & Immunotherapeutics, 2019
Backgroud: Beijing was hyper-endemic for hepatitis A until the 1990s and has been vaccinating against hepatitis A since 1994. The objective is to study the epidemiology and changes of antibody level of hepatitis A from 1990 to 2017. Methods: A multistage
Huai Wang, Pei Gao, Weixin Chen, Shuang Bai, Min Lv, Wenyan Ji, Xinghuo Pang, Jiang Wu   +7 more
doaj   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Raman Analysis of RNA Nucleotide Strands From SARS‐CoV‐2 Variants and Subvariants: A Step Forward in the Definition of “Raman Genome”

Advanced Science, EarlyView.
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti, Yoshiki Yasukochi, Gianluca Angiola, Takaharu Ueno, Saki Ikegami, Rintaro Okawa, Tetsuya Adachi, Wenliang Zhu, Osam Mazda, Alfio Grillo, Koichiro Higasa, Kazu Okuma   +11 more
wiley   +1 more source

Experiments with mathematical models to simulate hepatitis A population dynamics under different levels of endemicity

Cadernos de Saúde Pública
Heterogeneous access to sanitation services is a characteristic of communities in Brazil. This heterogeneity leads to different patterns of hepatitis A endemicity: areas with low infection rates have higher probability of outbreaks, and areas with higher
Mariana Alves de Guimaraens, Cláudia Torres Codeço   +1 more
doaj  

Epidemiological analyses of hepatitis A in Yuxi City of Yunnan Province from 1994 to 2023

Shanghai yufang yixue
ObjectiveTo analyze the reported‑case characteristics and incidence of hepatitis A in Yuxi City of Yunnan Province before (1994‒2008) and after (2009‒2023) the live attenuated hepatitis A vaccine was incorporated into the expanded program on immunization
CHEN Jingwen, XIONG Yanli, YU Haodong, BAO Lei, LI Zaiyou, AI Min, YANG Xiaojuan, LI Qiaofeng, HU Jinhui, CHEN Yixuan, WU Liqing, QI Kun, DENG Shuzhen   +12 more
doaj   +1 more source

[Hepatitis].

Revista de la Facultad de Medicina, Universidad Nacional de Colombia, 1956
En el hígado es difícil diferenciar los cambios inflamatorios, de los degenerativos y por esta causa, en un sentido histológico estricto, el término de hepatitis es difícil de precisar y ha sido motivo de múltiples discusiones, pero por razones prácticas en general se reserva para los procesos parenquimatosos agudos.
openaire   +2 more sources